The Nervous System Flashcards
What is meant by the term myogenic?
Muscle that contracts spontaneously without input from the nervous system
Name the three types of muscle
Skeletal muscle, smooth muscle and cardiac muscle
Striated muscle is made up of muscle________, each of which is made up of myofibrils.
Each myofibril is made up of myofilaments. The pattern of ________ myofilaments (made up of protein _______) and ________ myofilaments (made up of protein _______) gives the striation in the muscle
Fibres, thin, actin, thick, myosin
What is a neurotransmitter?
A chemical messenger that diffuses across a synapse
What is the cardiovascular centre?
A specific region of the medulla oblongata that receives sensory inputs about the levels of physical activity, blood CO2 concentration, and blood pressure.
It sends nerve impulses to the SAN in the heart to alter the frequency of excitation waves
What is the medulla oblongata?
A region found at the base of the brain, that coordinates the unconscious function of the body, such as breathing rate and heart rate
The accelerator nerve and the vagus nerve run from the medulla oblongata to the heart
What does myogenic mean?
Contraction if the muscle is generated from within the muscle itself
The term is used to describe the contraction of the heart, which is controlled by the action of SAN
What is resting potential?
The potential difference or voltage across the neurone cell membrane while the neurone is at rest
It is about -60mV inside the cell compared with the outside
Other cells may also maintain a resting potential that might change under certain circumstances
What are voltage gated channels?
Channels in the cell membrane that allow the passage of charged particles or ions
They have a mechanism called a gate which can open and close the channel
In these channels the gates respond to changes in the potential difference across the membrane
What is the threshold potential?
A potential difference across the membrane of about -50mV
If the depolarisation of the membrane does not reach the threshold potential then no action potential is created
If the depolarisation reaches the threshold potential then an action potential is created
What is an action potential?
A depolarisation of the cell membrane so that the inside of the cell membrane so that the inside is more positive than the outside, with a potential difference across the membrane of +40mV
This can be transmitted along the axon or dendron plasma membrane
What are local currents?
The movements of ions along the neurone
The flow of ions is caused by an increase in concentration at one point, which causes diffusion away for, the region of higher concentration
What are the first 4 stages of an action potential?
1 – The membrane starts in its resting state - polarised with the inside of the cell being -60mV compared to the outside
2 – Sodium ion channels open and some sodium ions diffuse into the cell
3 – The membrane depolarises - it becomes less negative with respect to the outside and reaches the threshold value of -50mV
4 – Voltage gated sodium ion channels open and many sodium ions flood in. As more sodium ions enter, the cell becomes positively charged inside compared with outside
What are the last 4 stages of an action potential?
5 – The potential difference across the plasma membrane reaches +40mV. The inside of the cell is positive compared with the outside
6 – The sodium ion channels close and potassium channels open
7 – Potassium ions diffuse out of the cell, bringing the potential difference back to negative inside compared with the outside - repolarisation
8 – The potential difference overshoots slightly, making the cell hyper polarised. The original potential difference is restored so that the cell returns to its resting state
Following stimulation, calcium ions binds to __________ on the actin filaments.
This cause another protein called __________ to change position and unblocked the binding sites on the actin filaments
Troponin
Tropomyosin
The myosin heads attach to the binding sites, forming _________
bridges between the two filaments
Actomyosin
_________ provides the energy for the cross-bridges to detach and reattach further along the actin filament
ATP
Explain what is meant by a spinal reflex
A rapid and automatic response to a stimulus that does not involve though processes in the brain
Name the three types of neurone involved in a spinal reflex, in order of their stimulation
Sensory neurone, relay neurone, motor neurone
A hand is placed on a hot object and immediately withdrawn
For this reflex action, name:
a) the stimulus
b) the receptor
c) the coordinator
d) the effector
a) Touching the hot object
b) Heat receptors in the hand
c) Reflex arc in the spinal cord
d) Muscles involved in the withdrawal of the hand
What is the autonomic nervous system?
The part of the nervous system that controls unconscious or involuntary activities, such as action of the heart or digestive system