the nervous system Flashcards
Neuron’s job
conduct electrochemiical impulses
Glial cells
support neurons, hold them together without touching
types of glial cells
astrocytes: clean up brain debris, transport nutrients
schwann cells
form myelin
Axon terminal
or synaptic terminals
have little bumps
contain synapric vesicles
have little sacs containing neurotransmitters
Node de Ranvier
where the axon is unprotected
axon
the long part of the neuron
can be covered in myelin sheath
myelin sheath
- Schwann cells
-increase speed of the neural impulse
-provides axon with nutrients and protexts it
-outer membrane is called neurilemma ; regenerate damaged neurons
cell body
aka soma, contains nucleus and neuroplasm
dendrites
extensions from soma
contain receptors
pick up electrical impulses
Saltatory conduction
impulses jump from one node to another
white matter
neurons contain myelin
grey matter
neurons that do not contain myelin
cannot be fixed once damaged (cognitive part of the brain)
types of neurons
- interneuron
- motor neuron
- sensory neuron
interneuron
carry impulses in the CNS
short axon without myelin
interprets sensory info and sends motor info
motor neuron
from CNS to the effectors
have long myelinated axons
sensory neurons
relay info from the environment to CNS
dendrites have sensory receptors disgned to receive external stimuli
long myelinated neurons
steps of neurotransmission
-resting neuron
-stimulated neuron
-depolarization
-repolarization
-refractry period
-the synapse
resting neuron
ICF is (-) with respect to ECF that is (+)
the membrrane is fairly impermeable to Na+ and mostly impermeable to K+
Na+ in ECF is 10x greater ICF
K+ in ICF is 30x greater than in ECF
Sodium-potassium pump
some ions leak through, the cell fix that with Sodium-Potassium pump (need ATP)
the way Sodium-potassium pump works
Na+ gets into the pump (with ATP) then it flips, Na+ gets out, K+ gets into the pump that flips again, releases K+ and ATP
what is a voltage?
the seperation in charge between ECF and ICF
the inside is negatively charged or POLARIZED
axon’s voltage equals to…
-70 mV
Stimulating a neuron
when neuron is stimulated, action potential begins (neurotransmission)
stimuli that can trigger a neuron to fire
chemicals, negatively charged electrodes, change in pH, mechanical deformation, heat/cold
treshhold level
around -55 mV
it is a minimum level of stimulus required
all or none response
either reaches the treshhold and fires or it doesn’t
Summation
two neurons can release neurotransmitters at the same time
Depolarization
(action potential 1)
Na+ channels opens
rush of Na+ into ECF due to diffusion
the inside becomes (+) (almost +40mV)
Na+ channels are found in the nodes of Ranvier
Repolarization
action potential 2
normal polarity must be restored
K+ channels open
K+ rushes out
action potential 2
normal polarity must be restored
K+ channels open
K+ rushes out
Na+/K+ pumps moves Na+ out and K+ in
refracotry period
time it takes to repolarize a membrane
if a second stimulus is applied, the neuron will not fire
the synapse
region between two nerve cells
neurotransmission passes through presynaptic neuron to postsynaptic neuron
cynaptic cleft
actual gap between presynaptic and postsynaptic neuron
what does the end of the axon contain?
synaptic vesicles that contain neurotransmitters
Acetylcholine (Ach)
is the neurotransmitter found most in the body
when the nerve impulse reaches the axon terminal…
a calcium channel opens up and Ca2+ rushes in
neurotransmitters get released into the synaptic cleft
neurotransmitters bind to the receptors in the postsynaptic membrane ina lock and key style
excitation- depolarization
positive ion channels (Na+ or Ca2+) opens up
positive ions rush in
reaches the treshhold
inhibition- hyperpolarization
K+ channels open up
K+ rushes out
Cl- channels open up
Cl- rushes in
neuron becomes more (-)
GABA
is the most common inhibitory neurotransmitter
why does the body need inhibitory neurotransmitters
-prioritize sensory info
-coordinate muscle mvt
-pain killers inhibit transmission
getting rid of neurotransmitters in the synapse
1.enzymes; break down transmitters
(cholinesterase; breaks down Ach)
2.re-uptake systems; allow neurotransmitters to be carried back inside the axon terminal.
organization of the nervous system
Nervous system: -central nervous system:-spinal cord + brain
-peripheral nervous system: *autonomic: involuntary: sympathetic and parasympathetic
*sensory-somatic nerves: voluntary: sensory neurons and motor neurons
spinal cord
runs from the sacrum into the brain through foramen magnum
large bundle of neurons
spinal cord is protected by…
vertebrae and 3 protected membranes called meninges
layers of spinal cord
outer layer is white matter
inner layer shaped H grey matter
the small hole running through the middle of the spinal cord is called
cerebrospinal canal contains cerebrospinal fluid that protects and carry nutrients and wastes to and from the spinal cord
how many roots each side has?
31 mixed spinal nerves
one half carries the sensory neurons, the other carries motor neurons
the 2 functions of the spinal cord?
- relaying info via interneurons from and to the brain
- the reflex arc
the reflex arc
automatic and involuntary response
1. sensory receptor
2.sensory neuron
3. interneuron
4.motor neuron
5.effector
protecting the brain
skull
3 membranes called meninges ( inflammation of these membranes is called meningitis)
and cerebrospinal fluid