The Kidney Flashcards

1
Q

Name the structure that delivers blood INTO the kidney?

A

The renal artery

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2
Q

Name the structure that delivers blood OUT OF the kidney

A

The renal vein

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3
Q

Blood from the renal artery enters _____________

A

Blood from the renal artery enters _ smaller arterioles in the cortex of the kidney

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4
Q

The _____ ______ takes blood into the glomerulus

A

The afférent artériole takes blood into the glomerulus

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5
Q

What is the glomerulus?

A

A bundle of capillaries looped inside the Bowman’s capsule

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6
Q

Ultrafiltration is also known as?

A

Glomerular filtration

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7
Q

The blood is under high pressure which causes ultrafiltration. Why is the blood under high pressure?

A

1) Pumped from aorta, high pressure as has to get around whole body
2) The afférent artériole is WIDER than the efferent artériole. This acts like when a lane is closed on the motorway.

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8
Q

State the three layers in glomerular filtration

A

1) Capillary fenestrations
2) Basement membrane
3) Bowman’s capsule epithelium (containing podocytes)

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9
Q

Describe capillary fenestrations in ultrafiltration

A

They contain large gaps which allow blood plasma through but not large objects like proteins and erythrocytes (red blood cells) through

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10
Q

Describe the basement membrane in ultrafiltration

A

It supports the cells of the capillary endothelium; acting as a fine filter allowing small plasma proteins through.
(The maximum size that can pass through is called the renal threshold and is a molecular mass of 68,000)

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11
Q

Describe the Bowman’s capsule epithelium (and podocytes) in ultrafiltration

A

The form the lining of the renal capsule and have large gaps between them which allow the glomerular filtrate through into the renal space

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12
Q

The outer section of the kidney is called?

A

The cortex

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13
Q

The inner section of the kidney is called?

A

The medulla

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14
Q

Selective réabsorption occurs along the…

A

PCT
Loop of Henle
DCT

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15
Q

PCT =

A

Proximal convoluted tubule

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16
Q

DCT =

A

Distal convoluted tubule

17
Q

State two adaptations of the PCT cells to enable selective reabsorption

A

1) High numbers of microvilli —> Increases the sa:vol ratio for the reabsorption of useful materials from the glomerular filtrate into the blood
2) High numbers of mitochondria —> More ATP able to be produced to power the active transport of substances

18
Q

Urine usually contains: (3 points)

A

1) Water & dissolved salts
2) Urea
3) Other substances such as hormones and excess vitamins

19
Q

Urine doesn’t usually contain: (2 points)

A

1) Proteins and blood cells –> they’re too big to be filtered out of the blood
2) Glucose, as its actively reabsorbed back into the blood

20
Q

The regulation of the blood’s water potential is called…

A

Osmoregulation

21
Q

When the water potential of the blood is too low…

A

1) More water is reabsorbed by osmosis into the blood from the nephron tubules
2) Urine is ore concentrated, less water is lost

22
Q

When the water potential of the blood is too high…

A

1) Less water is reabsorbed by osmosis into the blood from the nephron tubules
2) Urine is less concentrated, more water is lost

23
Q

Blood ADH level _____ when you’re dehydrated

A

Rises when you’re dehydrated

24
Q

BLood ADH level _____ when you’re hydrated

A

Lowers when you’re dehydrated

25
Q

Give the steps when your blood ADH level RISES…

The big 10 point question

A

(Rises… think MORE)

1) Water potential of blood DECREASES
2) Water moves OUT of osmoreceptors via osmosis
3) Cells DECREASE in volume
4) Sends a signal to other cells in the hypothalamus
5) Sends a signal to the posterior pituitary gland
6) MORE ADH released by the posterior pituitary gland
7) MORE vesicles containing water-permeable channels (aquaporins) to fuse with the membrane
8) DCT & collecting duct become MORE permeable to water
9) MORE water reabsorbed by osmosis
10) Small amount of highly-concentrated urine produced

26
Q

Give the steps when your blood ADH level LOWERS…

The big 10 point question

A

(Lowers… think LESS)

1) Water potential of blood INCREASES
2) Water moves IN of osmoreceptors via osmosis
3) Cells INCREASE in volume
4) Sends a signal to other cells in the hypothalamus
5) Sends a signal to the posterior pituitary gland
6) LESS ADH released by the posterior pituitary gland
7) LESS vesicles containing water-permeable channels (aquaporins) to fuse with the membrane
8) DCT & collecting duct become LESS permeable to water
9) LESS water reabsorbed by osmosis
10) Large amount of dilute urine produced