The Human Genome Project

Question 1

when did the Human Genome Project start ?

Answer 1

1990

Question 2

What was the main purpose of the Human Genome Project ?

Answer 2

the main purpose of the human genome project was to identify the entire genetic makeup of humans. The

Question 3

What did the Human Genome project discover ?

Answer 3

identified all the genes present in the DNA of humans, the sequence of these genes, and the identification of alleles that might be mutated in certain disease conditions.

Question 4

What is the whole genome shotgun sequencing process ?

Answer 4

cut DNA into small sections that are easy to sequence
use computer algorithms to align overlapping segments to assemble genome

Question 5

What happens to sequencing methods ?

Answer 5

are continuously updated and have become automated

Question 6

when the genome of simpler organisms is determined what does this allow ?

Answer 6

allows the proteome of the organism to be determined

Question 7

Why is it useful to be able to determine the proteome of smaller organisms ?

Answer 7

allows the identification of potential antigens for use in vaccine production

Question 8

What is the proteome ?

Answer 8

the full range of different proteins that the genome is able to create in a given time

Question 9

what is a genome ?

Answer 9

the complete set of genes present in a cell

Question 10

In complex organisms knowledge of the genome cannot be easily translated into the proteome. What causes this ?

Answer 10

the presence of non-coding introns and of regulatory genes

Question 11

Why is it easier to determine the proteome of prokaryotes ?

Answer 11

one circular piece of DNA not associated with histones
There are no introns