The heart Flashcards

1
Q

cardiac muscle cells

A

heart is composed of these muscles

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2
Q

cardiac cell functions

A
  • contract without stimulation by nervous system (contraction is myogenic)
  • branched, allowing for faster signal propagation and contraction in 3 dimensions
  • not fused together, but are connected by gap junctions at intercalated discs
  • have more mitochondria, as they are more reliant on aerobic respiration than skeletal muscle
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3
Q

cardiac cell structural features

A
  • longer period of contraction and refraction, which is needed to maintain a viable heartbeat
  • does not become fatigued
  • interconnected network of cells is separated between atria and ventricles, allowing them to contact separately
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4
Q

atrial contraction

A

within right wall of right atrium is specialized cluster of cardiomycocytes called sinoatrial node
- acts as primary pacemaker, controlling rate at which heart beats
- sends electrical signals

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5
Q

atrioventricular node

A
  • signals from SA node must be relayed through second note located within cardiac skeleton
  • AV node separates atrial and ventricular contractions
  • AV node propagates electrical signals more slowly than SA node, creating a delay in passing on the signal
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6
Q

ventricular contraction

A

occurs following excitation of atrioventricular node
- AV node sends signals down septum via Bundle of His
- Bundle of His innervates fibres in ventricular wall, which causes the cardiac muscle to contract

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7
Q

heart relaxation / diastole

A

after every contraction of the heart, there is a period of insensitivity to stimulation
- recovery period is long and allows heart to passively refill with blood between beats
- long recovery period also helps prevent heart tissue becoming fatigued

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8
Q

electrical activity

A

P wave: depolarization of atria in response to signalling from SA node (atrial contraction)
QRS complex: depolarization of ventricles (ventricular contraction), triggered by signals from AV node
T wave: repolarization of ventricles (ventricular relaxation) and completion of standard heart beat

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9
Q

cardiac output

A

the amount of blood the heart pumps through the circulatory system in 1 minute

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10
Q

effects of heart rate

A
  • exercise
  • age
  • disease
  • temperature
  • emotional state
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11
Q

control of heart rate

A
  • sympathetic nervous system and decreased by parasympathetic stimulation
  • increased hormonally via adrenaline
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12
Q

stroke volume

A

amount of blood pumped to body (from left ventricle) with each beat of the heart

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13
Q

changes in stroke volume

A

affect blood pressure - more blood or more pressure will increase overall pressure
- systolic bp is higher, as it represents the pressure of blood following contraction of heart
- diastolic bp is lower, as it represents the pressure of blood while heart is relaxing between beats

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14
Q

hypertension

A
  • abnormally high blood pressure (either systolic, diastolic, or both)
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15
Q

thrombosis

A

formation of a clot within a blood vessel that forms part of the circulatory system
- occurs in arteries when the vessels are damaged as a result of the deposition of cholesterol (atherosclerosis)
- Atheromas (fat deposits) develop in the arteries and significantly reduce the diameter of the vessel (leading to hypertension)
- high blood pressure damages the arterial wall, forming lesions known as atherosclerotic plaques
- If a plaque ruptures, blood clotting is triggered, forming a thrombus that restricts blood flow

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16
Q

Coronary heart disease

A

describes the condition caused by the build up of plaque within the coronary arteries
- age
- genetics
- obesity
- diseases
- diet
- exercise
- sex
- smoking

17
Q

artificial pacemaker

A

medical device that delivers electrical impulses to the heart in order to regulate heart rate which treats:
- Abnormally slow heart rates (bradycardia)
- Arrhythmias arising from blockages within the heart’s electrical conduction system

18
Q

fibrilation

A

rapid, irregular and unsynchronised contraction of the heart muscle fibres
- is treated by applying a controlled electrical current to the heart via a device called a defibrillator