The Guide Flashcards
Which statement about nonhuman primate housing is false?
A: Cage height should be sufficient for the animals to comfortably stand erect with their feet on the floor.
B: Because of their aggressive nature, nonhuman primates should usually be singly housed.
C: Plans for environmental and psychological enrichment for nonhuman primates should be developed and implemented.
D: For brachiating species cage height should be such that an animal can, when fully extended, swing from the cage ceiling without having its feet touch the floor.
B: Because of their aggressive nature, nonhuman primates should usually be singly housed.
what is the best definition of a laboratory animal as defined by the Guide?
A: Any warm-blooded animal produced for or used in research, testing, or teaching.
B: Any animal produced for or used in research, testing, or teaching.
C: Any invertebrate animal produced for or used in research, testing, or teaching,
D: Any vertebrate animal produced for or used in research, testing, or teaching.
D: Any vertebrate animal produced for or used in research, testing, or teaching.
What type of drug must be used with neuromuscular blocking agents?
A: Anticonvulsant
B: General Anesthetic
C: Antipyretic
D: Sedative of tranquilizer
B: General Anesthetic
Areas for quarantine, hazardous substance studies, and nonhuman primate rooms should be kept at _________ Pressure.
A: Atmospheric
B: Neutral
C: Postive
D: Negative
D: Negative
What word does the Guide use to express a strong recommendation to animal care and use programs?
A: May
B: Might
C: Must
D: Should
D: Should
Which action is an example of refinement?
A: Using 20 zebrafish per group instead of 20 rabbits.
B: Testing a drug in tissue culture instead of in mice.
C: Using fewer rabbits per group while obtaining the same level of statistical significance
D: Changing a postoperative analgesic from one that lasts 6 hours to one that lasts for 12 hours.
D: Changing a postoperative analgesic from one that lasts 6 hours to one that lasts for 12 hours.
What is not a function of the IACUC?
A: To review and approve animal use protocols
B: To review concerns involving the humane care and use of the laboratory animals
C: To inspect the animals facilities
D: To develop standard operating procedures for animal care husbandry staff.
D: To develop standard operating procedures for animal care husbandry staff.
Which statement about multiple survival surgical procedures on a single animal is TRUE?
A: The Animal Welfare Regulations allow for the interpretation of a “major” surgery to be evaluated on a case-by-case basis by the IACUC.
B: The Guide’s requirement that multiple major survival surgeries must be scientifically justified and included in the IACUC-approved protocol only applies to non-rodent mammals.
C: When USDA-covered species are used, the Animal Welfare Regulations’ definition of “major” surgery takes precedence.
D: The Guide’s definition of “major” surgery is rigid, and does not provide for any interpretation by the veterinarian or IACUC.
A: The Animal Welfare Regulations allow for the interpretation of a “major” surgery to be evaluated on a case-by-case basis by the IACUC.
Social animals should be housed___________
A: Singly, yet able to touch other animals.
B: Singly, yet able to see and hear other animals.
C: In the largest groups possible.
D: In pairs or groups.
D: In pairs or groups.
What is recommended for controlling noise in an animal facility ?
A: Attach sound-attenuating foam to the walls of an animal room.
B: Locate the cage wash facility next to housing areas.
C: Install double-door vestibules in noisy areas
D: Place fire alarm sirens in each animal room
C: Install double-door vestibules in noisy areas
Which category of drugs relieves pain?
A: Analgesics
B: Sedatives
C: Anxiolytics
D: Neuromuscular blocking drugs
A: Analgesics
For animals housed outdoors, any shelters provided to them should be:
A: Shoveled out daily.
B: Large enough to accommodate all the animals.
C: Painted regularly
D: Located near a water trough
D: Located near a water trough
Which animals are recommended to have the same minimum cager height according to the Guide?
A: Rats and guinea pigs
B: Guinea pigs and rabbits
C: Rabbits and cats
D: Mice and hamsters
A: Rats and guinea pigs
What does the Guide suggest doing to help animals avoid cold stress?
A: House as many animals as possible in one cage so that they can huddle together.
B: Raise the temperature in the room to the upper limit of the animals’ thermo-neutral zone.
C: Provide animals with nesting materials or shelters
D: Place electric heaters in the room when it becomes too cold.
C: Provide animals with nesting materials or shelters
Which statement about an HVAC system is FALSE?
A: Each institution’s HVAC system should maintain each room’s temperature by +/- 5℃.
B: Air intakes that remove air from the outside should be located away from vehicles and equipment that generate exhaust fumes.
C: Temperature is best regulated by having a separate thermostat control in each animal holding room.
D: The HVAC system should maintain the relative humidity in the 30-70% range.
B: Air intakes that remove air from the outside should be located away from vehicles and equipment that generate exhaust fumes.
In the Guide, which term means the physical structure that contains aquatic animals and the equipment used to move and/or treat their water?
A: Life support/system
B: Substrate
C: Microbial ecology
D: Primary enclosure
A: Life support/system
Standard laboratory animal diets can be stored for six months after the milling date except for which type of diet?
A: Certified diet
B: Irradiated det
C: Diet that contains non-stabilized vitamin C
D: Diet that contains non-stabilized vitamin A
C: Diet that contains non-stabilized vitamin C
Regarding space recommendations, at minimum, animals must:
A: Be able to circle the perimeter of their cage without encountering a feeder or waterer.
B: Have adequate space so that every animal has twice the minimum space for one animal.
C: Be able to touch the floor and the ceiling of the cage at the same time.
D: Have enough room to exhibit normal postural expressions without touching the enclosure walls or ceiling.
D: Have enough room to exhibit normal postural expressions without touching the enclosure walls or ceiling.
What term describes a statement of management direction or collective wisdom?
A: Principle
B: SOP
C: Policy
D: Procedure
C: Policy
What aquatic system uses the greatest quantities of water?
A: Re-circulating
B: Flow-through
C: Static
D: Closed
B: Flow-through
According to the Guide, how often must an IACUC meet?
A: At least annually
B: At least once for each study initiated at the institution
C: As often as necessary in order to fulfill their responsibilities
D: At least weekly
A: At least annually
