The Guide Flashcards

1
Q

Which statement about nonhuman primate housing is false?

A: Cage height should be sufficient for the animals to comfortably stand erect with their feet on the floor.
B: Because of their aggressive nature, nonhuman primates should usually be singly housed.
C: Plans for environmental and psychological enrichment for nonhuman primates should be developed and implemented.
D: For brachiating species cage height should be such that an animal can, when fully extended, swing from the cage ceiling without having its feet touch the floor.

A

B: Because of their aggressive nature, nonhuman primates should usually be singly housed.

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2
Q

what is the best definition of a laboratory animal as defined by the Guide?

A: Any warm-blooded animal produced for or used in research, testing, or teaching.
B: Any animal produced for or used in research, testing, or teaching.
C: Any invertebrate animal produced for or used in research, testing, or teaching,
D: Any vertebrate animal produced for or used in research, testing, or teaching.

A

D: Any vertebrate animal produced for or used in research, testing, or teaching.

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3
Q

What type of drug must be used with neuromuscular blocking agents?

A: Anticonvulsant
B: General Anesthetic
C: Antipyretic
D: Sedative of tranquilizer

A

B: General Anesthetic

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4
Q

Areas for quarantine, hazardous substance studies, and nonhuman primate rooms should be kept at _________ Pressure.

A: Atmospheric
B: Neutral
C: Postive
D: Negative

A

D: Negative

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5
Q

What word does the Guide use to express a strong recommendation to animal care and use programs?

A: May
B: Might
C: Must
D: Should

A

D: Should

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6
Q

Which action is an example of refinement?

A: Using 20 zebrafish per group instead of 20 rabbits.
B: Testing a drug in tissue culture instead of in mice.
C: Using fewer rabbits per group while obtaining the same level of statistical significance
D: Changing a postoperative analgesic from one that lasts 6 hours to one that lasts for 12 hours.

A

D: Changing a postoperative analgesic from one that lasts 6 hours to one that lasts for 12 hours.

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7
Q

What is not a function of the IACUC?

A: To review and approve animal use protocols
B: To review concerns involving the humane care and use of the laboratory animals
C: To inspect the animals facilities
D: To develop standard operating procedures for animal care husbandry staff.

A

D: To develop standard operating procedures for animal care husbandry staff.

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8
Q

Which statement about multiple survival surgical procedures on a single animal is TRUE?

A: The Animal Welfare Regulations allow for the interpretation of a “major” surgery to be evaluated on a case-by-case basis by the IACUC.
B: The Guide’s requirement that multiple major survival surgeries must be scientifically justified and included in the IACUC-approved protocol only applies to non-rodent mammals.
C: When USDA-covered species are used, the Animal Welfare Regulations’ definition of “major” surgery takes precedence.
D: The Guide’s definition of “major” surgery is rigid, and does not provide for any interpretation by the veterinarian or IACUC.

A

A: The Animal Welfare Regulations allow for the interpretation of a “major” surgery to be evaluated on a case-by-case basis by the IACUC.

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9
Q

Social animals should be housed___________

A: Singly, yet able to touch other animals.
B: Singly, yet able to see and hear other animals.
C: In the largest groups possible.
D: In pairs or groups.

A

D: In pairs or groups.

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10
Q

What is recommended for controlling noise in an animal facility ?

A: Attach sound-attenuating foam to the walls of an animal room.
B: Locate the cage wash facility next to housing areas.
C: Install double-door vestibules in noisy areas
D: Place fire alarm sirens in each animal room

A

C: Install double-door vestibules in noisy areas

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11
Q

Which category of drugs relieves pain?

A: Analgesics
B: Sedatives
C: Anxiolytics
D: Neuromuscular blocking drugs

A

A: Analgesics

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12
Q

For animals housed outdoors, any shelters provided to them should be:

A: Shoveled out daily.
B: Large enough to accommodate all the animals.
C: Painted regularly
D: Located near a water trough

A

D: Located near a water trough

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13
Q

Which animals are recommended to have the same minimum cager height according to the Guide?

A: Rats and guinea pigs
B: Guinea pigs and rabbits
C: Rabbits and cats
D: Mice and hamsters

A

A: Rats and guinea pigs

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14
Q

What does the Guide suggest doing to help animals avoid cold stress?

A: House as many animals as possible in one cage so that they can huddle together.

B: Raise the temperature in the room to the upper limit of the animals’ thermo-neutral zone.

C: Provide animals with nesting materials or shelters

D: Place electric heaters in the room when it becomes too cold.

A

C: Provide animals with nesting materials or shelters

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15
Q

Which statement about an HVAC system is FALSE?

A: Each institution’s HVAC system should maintain each room’s temperature by +/- 5℃.
B: Air intakes that remove air from the outside should be located away from vehicles and equipment that generate exhaust fumes.
C: Temperature is best regulated by having a separate thermostat control in each animal holding room.
D: The HVAC system should maintain the relative humidity in the 30-70% range.

A

B: Air intakes that remove air from the outside should be located away from vehicles and equipment that generate exhaust fumes.

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16
Q

In the Guide, which term means the physical structure that contains aquatic animals and the equipment used to move and/or treat their water?

A: Life support/system
B: Substrate
C: Microbial ecology
D: Primary enclosure

A

A: Life support/system

17
Q

Standard laboratory animal diets can be stored for six months after the milling date except for which type of diet?

A: Certified diet
B: Irradiated det
C: Diet that contains non-stabilized vitamin C
D: Diet that contains non-stabilized vitamin A

A

C: Diet that contains non-stabilized vitamin C

18
Q

Regarding space recommendations, at minimum, animals must:

A: Be able to circle the perimeter of their cage without encountering a feeder or waterer.
B: Have adequate space so that every animal has twice the minimum space for one animal.
C: Be able to touch the floor and the ceiling of the cage at the same time.
D: Have enough room to exhibit normal postural expressions without touching the enclosure walls or ceiling.

A

D: Have enough room to exhibit normal postural expressions without touching the enclosure walls or ceiling.

19
Q

What term describes a statement of management direction or collective wisdom?

A: Principle
B: SOP
C: Policy
D: Procedure

A

C: Policy

20
Q

What aquatic system uses the greatest quantities of water?

A: Re-circulating
B: Flow-through
C: Static
D: Closed

A

B: Flow-through

21
Q

According to the Guide, how often must an IACUC meet?

A: At least annually
B: At least once for each study initiated at the institution
C: As often as necessary in order to fulfill their responsibilities
D: At least weekly

A

A: At least annually