The Genetics of Sex Flashcards
Sex determination and Sex chromosomes
ultimately serve as the underlying basis of sex determination (present in both sex chromosome and autosome)
Gene
Mirror
Female
Spear and Shield
Male
Depends on efficient union if gametes for sexual differentiation
Successful Fertilization
In Eukaryotes, it is the ONLY NATURAL MECHANISM for producing new members of species
Sexual Reproduction
In year 1891, he mentioned about nuclear structure in the sperm of certain insects pertains to X-BODY
Hermann Henking
In year 1891, he mentioned about sperm in grasshoppers have an unusual genetic structure which is mistakenly associated as male progeny
Clarence McClung
In 1906, he mentioned about female (XX) somatic cells in the butterfly Protenor which has 14 chromosomes
Add info:
> Oogenesis → reduction occurred → gametes w/ 7 chr + 1 X chr
> Spermatogenesis
○ Gametes w/ 6 chr w/out X chr
○ Gametes w/ 7 chr, one of which is X
Edmund B.Wilson
Sex determination where the heterogametic sex (male is XO), it produces _____ chromosome
gametes with or without X
produce unlike gametes (heterogametic sex)
○ gametes ultimately determine the sex of the progeny
Male
Sex determination where the heterogametic sex (male is XY), it produces _____ chromosome
gametes either an X or a Y
has like sex chromosomes (homogametic sex)
○ uniform gametes with regard to chromosome numbers and types
Female
> tall, long arms and legs
Genitalia and internal ducts that are male
testes are reduced in size (50% affected produce sperm)
low sperm count renders most individuals sterile.
Klinefelter Syndrome (XXY)
> Feminine sexual development is not entirely suppressed
Gynecomastia is common, and the hips are often rounded.
Show no cognitive reduction
Individuals are unaware of having the disorder
not until they are treated for INFERTILITY
Klinefelter Syndrome (XXY)
> has female external genitalia and internal
ducts, but the ovaries are rudimentary.
● Other characteristic abnormalities:
○ short stature (usually under 5 feet)
○ skin flaps on the back of the neck
○ underdeveloped breasts
○ A broad, shieldlike chest
○ Intelligence is usually normal
Turner Syndrome (XO)
> triplo-X, occurs in about 1 of 1000 female births.
Perfectly normal
○ Unaware of their abnormality in chromosome number
unless a karyotype is done.
underdeveloped secondary sex
characteristics, sterility, delayed development of language and motor skills, and intellectual disability may occur.
presence of additional X chromosomes (disrupt the delicate balance of genetic
information essential to normal female
development)
47,XXX Syndrome
> 9 of 315 males in a Scottish maximum security prison had the 47,XYY karyotype.
These males were significantly above average in height and had been incarcerated as a result of dangerous, violent, or criminal propensities.
Of the 9 males studied, 7 had subnormal
intelligence, and all suffered personality disorders
Above-average height (usually over 6 feet)
subnormal intelligence were substantiated,
Another study proved many XYY males present in the population who do not exhibit antisocial behavior and who lead normal lives.
○ there is a high, but not constant, correlation between the extra Y chromosome and the predisposition of these males to exhibit behavioral problems
47,XYY Condition
Physical features:
○ include increased belly fat
○ a large head (macrocephaly)
○ unusually large teeth (macrodontia)
○ flat feet (pes planus)
○ fifth fingers that curve inward (clinodactyly)
○ widely spaced eyes (ocular hypertelorism),
○ abnormal side-to-side curvature of the spine
(scoliosis)
47,XYY Condition
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