THE GENETIC CODE Flashcards
What three words are the genetic code described as being?
universal
degenerate
non-overlapping
What does universal mean?
In almost all living organisms, the same triplet of DNA based codes for the same amino acid
How many proteinogenic amino acids are there?
22 BUT 20 FOUND IN THE BODY but 2 are incorporated by special translation mechanisms.
How many combinations of amino acids are there?
4 cubed = 64
What does degenerate mean?
each amino acid is encoded for by more than one codon
Because of this it is possible for substitution to occurs that changed a single base if DNA but no change occurs in the primary structure of the polypeptide
What are the three types of gene mutations?
base substitution
base insertation
base deletion
Which type of mutation has the smallest effect and why?
base substitution because the others have a knock-on effect -a reading frame shift
what is another word for a triplet on mRNA
codon
what is another word for a triplet on the tRNA
anticodon
What is in each end of the tRNA?
one end has the amino acid and the other end has the anticodon
what is a particular sequence of DNA nucleotide bases or a chromosome called?
a gene
Why does the primary structure affect the secondary structure of a protein?
different sequence of amino acid affects the R groups and the interaction between these R groups which changes the secondary structure as it affect interactions here and this affects the tertiary structure and so on