THE ENDOCRINE SYSTEM Flashcards
what is the endocrine system?
a collective term for all endocrine glands and hormone-secreting cells distributed throughout the body
what is the endocrine gland/cell?
- lacks duct
- secretes their hormone into surrounding tissue/fluid and it is taken up by the blood and carried thorugh the body
what is the neuroendocrine/neurosecretory cell?
neurons that produce and release their secretions/hormones in response to signal from the nervous system
what are hormones?
- chemical messengers secreted into the bloodstream that produce a response only in certain TARGET CELLS that possess a receptor
- control and coordinate the body’s metabolism, energy level, reproduction, growth and development, and response to injury, stress, and mood
what 2 glands have broader effects than any other endocrine glands in the body?
hypothalmus and pituitary
where is the hypothalamus located?
region of forebrain located below thalamus and posterior to optic chiasma
what kind of connections does the hypothalamus have to the pituitary?
the hypothalamus has both neural and circulatory connections with pituitary gland
the hypothalamus is made of a collection of ____.
nuclei within diencephalon of brain with variety of functions including:
hormone regulation and secretion primarily from pituitary gland
autonomic regulation (HR, BP, GI secretions and motility)
thermoregulation
food and water intake
sleep and circadian rhythms
memory
emotional behavior
where is the pituitary gland located?
seated in sella turcica of sphenoid bone just below hypothalamus
attached to hypothalamus by stalk-like structure called infundibulum
also connected to hypothalamus via nerve fibers via circulation
how many lobes does the pituitary consist of?
2 lobes- anterior and posterior
which gland is considered the “master endocrine gland”?
pituitary
what does the pituitary do?
secrete several hormones and regulated the activity of other hormone-secreting glands
what is the primary regulator of the pituitary?
hypothalamus
what are the nerve fiber connections that connect the pituitary to hypothalamus called?
hypothalamohypophysial tract
what is the hypothalamohypophysial tract?
neurons in paravetnricular and supraoptic nuclei have direct projections that end in posterior pituitary
what does paraventricular nuclei produce and what does it do?
- produces oxytocin
- stimulated uterine contractions in labor and milk release during lactation
what does supraoptic nuclei produce and what does it do?
- primarily produces ADH
- vasoconstrictor that stimulated increase absorption of water from renal tubules
what are bloodstream connections in pituitary gland called and where does the blood stream come from?
- hypothalamohypophysial portal system
- formed by branches off the internal carotid arteries
what occurs in the hypothalamohypophysial portal system?
arteries travel through median eminence (pituitary “stalk”) -> capillaries that surround cells within anterior pituitary
what kind of cells are located in medial zone of hypothalamus and have projections to the median eminence and secrete hormones into portal system?
neurosecretory cells