The digestive System Mnemonics Flashcards
Name four antacids and four side-effects or interactions that
concern you about antacids
ACIDIC MEALS
A_____________________ (antacid)
C_____________________ (antacid)
I
D_________P__________ (side effect)
I__________C__________ (drug interaction)
C_____________________ (side effect)
M_____________________ (antacid)
E
A_____ N______________ (when / how to take antacids)
L_____________________ (side effect of magnesium hydroxide)
S_____________________ (antacid)
1. ANTACIDS– ACIDIC MEALS
Aluminum hydroxide (Amphojel)
Calcium carbonate (Tums, Pepto
Children’s)
I
Decreased phosphate with Al(OH)3, CaCO3,
Mg(OH)2
Ions, chelation with fluoroquinolones,
levothyroxine, and tetracyclines
Constipation from Al(OH)3 and CaCO3
Magnesium hydroxide (Milk of Magnesia)
E As needed (
PRN) rather than scheduled
Laxative effect of magnesium hydroxide
Sodium bicarbonate (in Alka-Seltzer
Question 2. Name four histamine-2 receptor blockers, their class
suffix, two specific concerns about cimetidine, one about
cimetidine and famotidine, and a general concern for the drug class
itself.
CALIFORNIA H2
C _____________________( histamine-2 receptor blocker)
A_____________________ (concern for cimetidine)
L_____________________ (concern for cimetidine)
I_____________________ (concern for cimetidine and famotidine)
F_____________________ (histamine-2 receptor blocker)
O
R_____________________ (histamine-2 receptor blocker)
N_____________________ (histamine-2 receptor blocker)
I
A______ for R______ D_________ (general class concern)
2. HISTAMINE-2 RECEPTOR ANTAGONISTS (H2RAS) –
CALIFORNIA H2
Cimetidine (Tagamet)
Androgenic effect gynecomastia with
cimetidine
Liver enzymes interaction (CYP450) with
cimetidine
Increases QTc with other QTc, famotidine
and cimetidine
Famotidine (Pepcid)
O
Ranitidine (Zantac)
Nizatidine (Axid)
I
Adjust for renal disease
Question 3. Name eight drugs and or drug classes that might cause
gynecomastia.
FEMALE PARTS CARE
P_____________________ (HIV drug class)
A_____________________ (Hormone drug class)
R__________ T_________ (HIV drug class)
S_____________________ (Diuretic drug)
C_____________________ (H2RA)
A_____________________ (hormone drug class)
R_____________________ (Antipsychotic drug)
E_____________________ (Hormone drug class)
P rotease inhibitors
A ntiandrogens
R everse-
T ranscriptase inhibitors
S pironolactone (Aldactone)
C imetidine (Tagamet)
A nabolic steroids
R isperidone (Risperdal)
Es trogens
Question 4. Name six proton pump inhibitors and their class suffix.
ULCER DEVELOPER
D_____________________ (PPI right enantiomer)
E______________________ (PPI left enantiomer)
V
E
L______________________ (PPI)
O______________________ (PPI)
P______________________ (PPI)
E
R______________________ (PPI)
Class suffix
-p_____________________
4. PROTON PUMP INHIBITORS (PPIS) – ULCER
DEVELOPER
Dexlansoprazole (Dexilant)
Esomeprazole (Nexium)
VE
Lansoprazole (Prevacid)
Omeprazole (Prilosec)
Pantoprazole (Protonix)
E Rabeprazole (AcipHex)
Question 5. Name seven possible side-effects or interactions of proton pump
inhibitors.
ULCER DEVELOPER SIDE EFFECTS
Side-effects
D______________________ (side effect)
E_______________________ (side effect)
V
E_______________________ (interaction)
L_______ M______________ (side effect)
O_______________________ (side effect)
P________________________ (side effect)
E
R_________ H____________ (side effect)
DEVELOPER SIDE EFFECTS
Diarrhea from Clostridium difficile infection
Elderly, to remind us of dementia
V Enzymes (
CYP issues with some PPIs)
Low magnesium
Osteopenia (bone loss), a concern forfractures
Pneumonia
E Rebound hypersecretion
Question 6. Name two antibiotics in a triple peptic ulcer disease regimen and
how we dose the PPI.
ACED PUD
Drugs for a triple peptic ulcer disease regimen
A_____________________ (penicillin)
C_____________________ (macrolide)
E_____________________ (PPI)
How to dose the PPI in PUD
D__________ D___________
ACED PUD
Amoxicillin (Moxatag)
Clarithromycin (Biaxin)
Esomeprazole (Nexium)
Double dosing of the PPI
Question 7. Name four drugs in each of two quad peptic ulcer disease
regimens.
BED-MIDNIGHT OR MACE
Quad peptic ulcer disease regimen #1
B _____________________ (antidiarrheal)
E_____________________ (PPI)
D_____________________ (tetracycline)
M_____________________ (nitroimidazole)
Quad peptic ulcer disease regimen #2
M____________________ (nitroimidazole)
A_____________________ (penicillin)
C_____________________ (macrolide)
E_____________________ (PPI)
MIDNIGHT OR MACE
Bismuth subsalicylate (Pepto-Bismol)
Esomeprazole (Nexium)
Doxycycline (Vibramycin)
Metronidazole (Flagyl)
Metronidazole (Flagyl)
Amoxicillin (Moxatag)
Clarithromycin (Biaxin)
Esomeprazole (Nexium)
Question 8. Name six medications known to cause the disulfiram reaction
and the reaction’s underlying mechanism.
MEGA PUCED
Disulfiram reaction medications
Me________________________ (nitroimidazole antibiotic)
G_________________________ (antifungal)
A________ of A_____________ (underlying mechanism)
P_________________________ (chemotherapy)
U
Ce_____________________ and Ce_____________________
(cephalosporin antibiotics)
D_________________________ (for alcoholism)
Metronidazole (Flagyl)
Griseofulvin (GrifulvinV)
Accumulation of acetaldehyde, a toxic metabolite
Procarbazine (Matulane)
U
Cefotetan (Cefotan, 2nd) and
Cefoperazone (Cefobid, 3rd)
Disulfiram (Antabuse)
Question 9. Name a prostaglandin-like drug to protect the stomach, two
prokinetics, and a protectant.
MIMES STUCK IN STOMACH
Mi____________________ (prostaglandin-like drug)
M_____________________ (prokinetic)
E_____________________ (prokinetic, antibiotic)
S_____________________ (protectant)
PROTECTANT – MIMES STUCK IN STOMACH
Misoprostol (Cytotec)
Metoclopramide (Reglan)
Erythromycin (E-Mycin)
Sucralfate (Carafate)
Question 10. In order of aggressiveness of therapy from least to most, name
three antidiarrheal or combination drugs.
BUILD A BARRIER
B_____________________ (salicylate, least aggressive)
U
I
L_____________________ (opioid receptor agonist)
D_____________________ /
A______________________ (opioid, anticholinergic combination, most
aggressive)
BARRIER
10. HAVEDIARRHEA? – BUILD A BARRIER
Bismuth subsalicylate (Pepto-Bismol)
UI
Loperamide (Imodium)
Diphenoxylate /
Atropine (Lomotil)
Question 11. Name the six anticholinergic side-effects that you might expect
with a drug like atropine.
ABDUCT WATER
A______________________
B__________ V__________
D__________ M_________
U__________ R__________
C______________________
T______________________
ABDUCT WATER
Anhidrosis, lack of sweating
Blurry vision, secondary to dry eyes
Dry mouth or xerostomia
Urinary retention
Constipation
Tachycardia
Question 12. Name six cholinergic side-effects.
SLUDGE WATER
S_______________________
L_______________________
U___________ I___________
D_______________________
G___________ D__________
E_______________________
CHOLINERGIC SIDE EFFECTS– SLUDGE WATER
Salivation, opposite dry mouth
Lacrimation, opposite blurry vision with dry eyes
Urination incontinence, opposite urinary retention
Diarrhea, opposite constipation
Gastric distress and
Emesis
Question 13. In order of least to most aggressive treatment, name four drugs
for constipation.
PRE-DISPOSED
P_________________________ (fiber)
R
E
D_________________________(stool softener)
I
S_________________________ (stimulant)
PO_____________ G________ (osmotic)
S
E
DO
Psyllium (Metamucil)
RE
Docusate sodium (Colace)
I
Senna (Senokot)
Polyethylene glycol (GoLytely, MiraLAX)
S
E
D
Question 14. Name an antivertigo drug for cruise ship travel. Name two
drugs you would use to prevent CINV, one drug that you would add on if the
first two don’t work alone, and a PO and IV drug for delayed emesis.
STOP ADD AFTER
S_____________________ (for cruise ship travel)
T
O_____________________ (to prevent CINV)
P______________________ (to prevent CINV)
A
D
D_____________________ (add-on drug to prevent CINV)
A_____________________ (PO drug for delayed emesis)
F______________________ (IV drug for delayed emesis)
T
E
R
Scopolamine (Transderm-Scop)
T
Ondansetron (Zofran)
Palonosetron (Aloxi)
A
D
Dexamethasone (Decadron)
Aprepitant (Emend)
Fosaprepitant (Emend injectable)
TER
Question 15. Name two drugs that come in suppository form to prevent
vomiting.
PROVIDE MAGAZINE
1. PRO___________AZINE
2. PRO___________AZINE
PROVIDE MAGAZINE
Prochlorperazine (Compazine)
Promethazine (Phenergan)