The Depressed Brain

Question 1

What is the diagnostic criteria for major depression?

Answer 1

Lecture 17, slide 5-6

Question 2

Summarise some explanations for depression?

Answer 2

Lecture 17, slide 7

Question 3

What are the different types of antidepressants?

Answer 3

Lecture 17, slide 10

Question 4

What are SSRIs?

Answer 4

Lecture 17, slide 11

Question 5

What are antidepressants used to treat? How well do they work?

Answer 5

Lecture 17, slide 12

Question 6

What is the serotonin hypothesis of depression?

Answer 6

Lecture 17, slide 15, 28

Question 7

Do SSRIs work?

Answer 7

Lecture 17, slide 16-17

Question 8

What acute tryptophan depletion? Does it support the serotonin hypothesis of depression? What does it reveal?

Answer 8

Lecture 17, slide 19-25

Question 9

Does serotonin have an effect on emotion-processing?

Answer 9

Lecture 17, slide 26-27

-serotonin seems to have cognitive improvements before mood improvement s

Question 10

What is the role of the amygdala? How is the amygdala implicated in depression?

Answer 10

Lecture 17, slide 31-34

Question 11

What is the role of the hippocampus? How is the hippocampus implicated in depression?

Answer 11

Lecture 17, slide 35-37

Question 12

What is the role of the prefrontal cortex? How is the prefrontal cortex implicated in depression?

Answer 12

Lecture 17, slide 38-39

Question 13

What is the role of the dorsolateral PFC? How is the dorsolateral PFC implicated in depression?

Answer 13

Lecture 17, slide 40-41

Question 14

What is the role of the OFC? How is the OFC implicated in depression?

Answer 14

Lecture 17, slide 42-43

Question 15

How is the subgenual ACC implicated in depression?

Answer 15

Lecture 17, slide 44-46

Question 16

Is DBS effective for treatment-resistant depression? Suggest possible mechanisms for its action.

Answer 16

Lecture 17, slide 47-49