The Cell Cycle and gene mutations Flashcards
Components of cell cycle
G1, S, G2, mitosis
G1 phase
Cell grows and increases protein content and organelles’ number increases
S phase
Cell replicates its DNA, ready to divide by mitosis
G2 phase
Rapid cell growth and protein synthesis of proteins needed in cell division
Stages of mitosis in order
Prophase, Metaphase, Anaphase, Telophase
Prophase
Chromosomes condense and arranged randomly throughout cytoplasm of cell. Centrioles move to opposite ends of spindle.
Metaphase
Chromosomes line up along equator of cell and attach to spindle by their centromere
Anaphase
Sister chromatids pulled apart by spindle fibres by the centromere. Spindles contract moving them to opposite poles of cell, centromere first.
Telophase
Chromatids reach opposite poles. Uncoil and become long and thin again. Nuclear envelope forms around each group of chromosomes and cytokinesis occurs.
What is conjugation
Process of DNA being passed from one species of bacterium to another
Process of conjugation
- One cell produces thin projection that meets another cell - Conjugation tube
- Donor cell replicates one of its plasmids
- Plasmid broken to make it linear, so it can pass through conjugation tube
- Recipient cell acquires new characteristics from donor cell
Horizontal gene transmission
Transmission of DNA from one species of bacteria to another
What are gene mutations?
Change to base sequence of DNA caused by spontaneous errors in DNA replication. Rate of mutations increased by mutagens
How do mutagens increase rate of mutations?
- Acting as bases
- Altering bases
- Changing structure of DNA