The Balls Flashcards

1
Q

Hypogonadism:

A

-low T

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2
Q

Hypogonadism etiology:

A

Primary: Testicular failure (ex. mumps orchitis)
Secondary: Hypogonadotropic hypogonadism (age-related (ADAM), chronic opiates)

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3
Q

Hypogonadism etiology:

A

increasingly diagnosed

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4
Q

hypogonadism presentation:

A

-decreased energy/fatigue, ED, decreased force of ejaculation, decreased libido

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5
Q

hypogonadism work-up:

A
  • free and total testosterone
  • exam
  • if low- DEXA scan
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6
Q

hypogonadism tx:

A
  • Androgen (testosterone) supplementation

- gels, injections, pellets

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7
Q

Hypogonadism follow-up/monitoring:

A
  • PSA, hemogram (H&H), testosterone, review of urinary symptoms, DRE
  • 3, 6 and 12 months after initiating, then annual
  • Counsel prostate Ca monitoring; CV risks, infertility.
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8
Q

ADAM questionnaire:

A

This basic questionnaire can be very useful for men to describe the kind
and severity of their low testosterone symptoms.
1. Do you have a decrease in libido (sex drive)? Yes No
2. Do you have a lack of energy? Yes No
3. Do you have a decrease in strength and/or endurance? Yes No
4. Have you lost height? Yes No
5. Have you noticed a decreased “enjoyment of life” Yes No
6. Are you sad and/or grumpy? Yes No
7. Are your erections less strong? Yes No
8. Have you noticed a recent deterioration in your ability to play sports? Yes No
9. Are you falling asleep after dinner? Yes No
10. Has there been a recent deterioration in your work performance? Yes No
If you Answer Yes to number 1 or 7 or if you answer Yes to more than 3 questions, you may have low Testosterone.

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9
Q

Cryptorchidism:

A

testis (testes) not in scrotum

  • Possibly absent; possibly non-palpable (20%); if palpable, won’t come down
  • RARE
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10
Q

Cryptorchidism etiology:

A

not well understood

-Normal descent is androgen-independent, mediated by “descendin;” passage through inguinal canal begins 28 weeks

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11
Q

Cryptorchidism work-up:

A
  • good physical exam (never forget the penis)
  • possible scrotal US
  • urologist may pursue more studies
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12
Q

tx of cryptorchidism:

A

hormonal manipulation (GnRH injection); orchidopexy

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13
Q

Places of cryptorchidism:

A

Inguinal canal - between internal and external rings

Intra-abdominal (10%) - proximal to inguinal ring

Absent testis (20%)- truly absent, probable vascular event

Ectopic testis - below the internal ring but out of normal path

Retractile testis - reflects exuberant cremasteric reflex
-Follow patient until puberty

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14
Q

Descending of the testis:

A

Most descend spontaneously in first 3 months
If undescended at 6 months, descent is unlikely

3% of term infants, 30% of premature infants

10% bilateral
3% have one or both testes absent

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15
Q

risk factors of cryptorchidism:

A

Risk Factors:

Twins, low birth weight, pre-term delivery, family history, Prune Belly syndrome

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16
Q

risks from cryptorchidism:

A
  • Ca
  • -CA less likely if undescended testis was in inguinal canal vs. abdomen
  • decreased fertility
  • Torsion risk is 10% higher
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17
Q

Orchidopexy

A

putting the ball where it belongs

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18
Q

Hydrocele:

A

benign accumulation of serous fluid between layers of tunica vaginalis

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19
Q

infant hydrocele presentation:

A

infant/toddler with hemiscrotal enlargement; volume/size waxes and wanes during day

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20
Q

Infant hydrocele etiology:

A

patent processus vaginalis (communicating hydrocele)

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21
Q

Infant hydrocele work-up:

A

clinical diagnosis; scrotal sonogram may be helpful

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22
Q

Infant hydrocele tx:

A

if persistent after one year, repair via inguinal incision

23
Q

Adult hydrocele presentation:

A

scrotal discomfort; scrotal enlargement; possible h/o trauma or infection

24
Q

adult hydrocele etiology:

A

idiopathic; post-traumatic; post-infectious

25
Q

adult hydrocele work-up

A

careful physical examination; transillumination; possible scrotal sonogram

26
Q

Adult hydrocele tx:

A
  • Expectant management if asymptomatic
  • Aspiration/sclerosis associated with recurrence
  • Scrotal excision (hydrocelectomy)
27
Q

Varicocele:

A

congestion of veins around testis

28
Q

varicocele epidemiology:

A

age 15-30, rarely over 40

29
Q

varicocele etiology:

A

reflects valvular anomaly exacerbated (or caused?) by gonadal venous anatomy; rare malignant etiology (consider if right-sided, or in man > 40 years)

30
Q

varicocele presentation:

A

asymptomatic; dull ache; infertility; scrotal enlargement; majority on left

31
Q

Varicocele work-up:

A

Clinical diagnosis; “bag of worms” due to dilatation of veins in pampiniform plexus; examine both standing and supine; generally no need for imaging; ?SA

32
Q

varicocele tx:

A

varicocelectomy; embolization; 2/3 surgically treated have fertility improvement

33
Q

Testicular torsion:

A

twisting of spermatic cord causing ischemia of testis

34
Q

testicular torsion epi:

A

bimodal distribution

Neonatal (extravaginal) v. pubertal (intravaginal)

35
Q

testicular torsion etiology:

A

anatomic predisposition (Bell-clapper deformity; cryptorchidism); trauma; sex

36
Q

testicular torsion presentation:

A

Sudden severe onset unilateral scrotal pain; nausea/emesis; abdominal pain; symptoms may be intermittent (intermittent torsion)

37
Q

testicular torsion work-up:

A

Difficult exam; high-riding testis; ?negative cremasteric reflex on affected side; scrotal edema and tenderness; pain unrelieved by scrotal elevation
Sonogram often equivocal or may be misleading, could delay treatment
High index of suspicion

38
Q

testicular torsion tx:

A

Scrotal exploration, with untwisting of cord and orchidopexy; ?contralateral orchidopexy
High salvage rate if treated within 6 hours

39
Q

Epididymitis:

A

inflammation or infection of epididymis

40
Q

epididymitis etiology:

A

-Ascending infection from urethra, prostate, bladder
<35 years - C. trachomatis, N. gonorrhoeae
>35years - E.coli
-Surgery (vasectomy)
-Other trauma

41
Q

epididymitis presentation:

A
  • scrotal pain
  • scrotal enlargement
  • fever
42
Q

epididymitis work-up:

A

Good history and exam; UA C&S; ?penile swab/probe for STI, ?scrotal sonogram

43
Q

epididymitis tx:

A
  • Antibiotics (empiric by age, i.e. doxycycline or ciprofloxacin)
  • Palliatives (scrotal support, NSAIDs, ice, narcotics)
44
Q

orchitis:

A

acute inflammatory reaction of testis secondary to infection

45
Q

orchitis etiology:

A

Most common – viral mumps infection in children
Bacterial orchitis - most commonly associated with epididymitis in sexually active males and men >50 with BPH
C. trachomatis, N. gonorrhoeae, E. coli

46
Q

orchitis presentation:

A
  • Scrotal pain (mild-severe) and swelling
  • Exam can reveal impressive induration and edema
  • Overlying skin frequently thickened
  • Testicle won’t move freely in the scrotum, seems “stuck”
47
Q

orchitis work-up:

A

Good history and exam; UA C&S; ?penile swab/probe for STI, ?scrotal sonogram

48
Q

orchitis tx:

A
  • Viral (mumps orchitis) - no medications; may lead to infertility
  • Bacterial - treat suspected organism, exclude/address abscess
49
Q

testis cancer histology:

A
  • Germ cell (95%):
  • -Seminoma
  • -Non-seminoma (NSGCT)
  • -Mixed (managed as NSGCT)
  • Non germ cell (5%)
  • Rare secondary tumors (lymphoma, leukemia)
50
Q

testis cancer presentation:

A

painless testicular mass
Usually incidental by partner or after trauma
Cough or dyspnea secondary to lung metastases
GI symptoms secondary to retroperitoneal metastases
Gynecomastia

51
Q

testis ca work-up:

A

Scrotal sonogram
Tumor markers (AFP, beta-hCG, LDH);
CT to assess the lymph nodes of retroperitoneum
Radical inguinal orchiectomy

52
Q

testis ca tx:

A

guided by histology (seminoma v. NSGCT) and staging (markers + imaging)
Surveillance
Adjuvant chemotherapy
Adjuvant radiotherapy
Retroperitoneal lymph node dissection (RPLND)

53
Q

testis ca prognosis:

A

Cure rate 90% for seminoma (all stages combined)

Cure rate approaches 100% for low-grade NSGCT