The Balls Flashcards

1
Q

Hypogonadism:

A

-low T

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2
Q

Hypogonadism etiology:

A

Primary: Testicular failure (ex. mumps orchitis)
Secondary: Hypogonadotropic hypogonadism (age-related (ADAM), chronic opiates)

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3
Q

Hypogonadism etiology:

A

increasingly diagnosed

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4
Q

hypogonadism presentation:

A

-decreased energy/fatigue, ED, decreased force of ejaculation, decreased libido

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5
Q

hypogonadism work-up:

A
  • free and total testosterone
  • exam
  • if low- DEXA scan
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6
Q

hypogonadism tx:

A
  • Androgen (testosterone) supplementation

- gels, injections, pellets

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7
Q

Hypogonadism follow-up/monitoring:

A
  • PSA, hemogram (H&H), testosterone, review of urinary symptoms, DRE
  • 3, 6 and 12 months after initiating, then annual
  • Counsel prostate Ca monitoring; CV risks, infertility.
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8
Q

ADAM questionnaire:

A

This basic questionnaire can be very useful for men to describe the kind
and severity of their low testosterone symptoms.
1. Do you have a decrease in libido (sex drive)? Yes No
2. Do you have a lack of energy? Yes No
3. Do you have a decrease in strength and/or endurance? Yes No
4. Have you lost height? Yes No
5. Have you noticed a decreased “enjoyment of life” Yes No
6. Are you sad and/or grumpy? Yes No
7. Are your erections less strong? Yes No
8. Have you noticed a recent deterioration in your ability to play sports? Yes No
9. Are you falling asleep after dinner? Yes No
10. Has there been a recent deterioration in your work performance? Yes No
If you Answer Yes to number 1 or 7 or if you answer Yes to more than 3 questions, you may have low Testosterone.

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9
Q

Cryptorchidism:

A

testis (testes) not in scrotum

  • Possibly absent; possibly non-palpable (20%); if palpable, won’t come down
  • RARE
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10
Q

Cryptorchidism etiology:

A

not well understood

-Normal descent is androgen-independent, mediated by “descendin;” passage through inguinal canal begins 28 weeks

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11
Q

Cryptorchidism work-up:

A
  • good physical exam (never forget the penis)
  • possible scrotal US
  • urologist may pursue more studies
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12
Q

tx of cryptorchidism:

A

hormonal manipulation (GnRH injection); orchidopexy

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13
Q

Places of cryptorchidism:

A

Inguinal canal - between internal and external rings

Intra-abdominal (10%) - proximal to inguinal ring

Absent testis (20%)- truly absent, probable vascular event

Ectopic testis - below the internal ring but out of normal path

Retractile testis - reflects exuberant cremasteric reflex
-Follow patient until puberty

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14
Q

Descending of the testis:

A

Most descend spontaneously in first 3 months
If undescended at 6 months, descent is unlikely

3% of term infants, 30% of premature infants

10% bilateral
3% have one or both testes absent

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15
Q

risk factors of cryptorchidism:

A

Risk Factors:

Twins, low birth weight, pre-term delivery, family history, Prune Belly syndrome

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16
Q

risks from cryptorchidism:

A
  • Ca
  • -CA less likely if undescended testis was in inguinal canal vs. abdomen
  • decreased fertility
  • Torsion risk is 10% higher
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17
Q

Orchidopexy

A

putting the ball where it belongs

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18
Q

Hydrocele:

A

benign accumulation of serous fluid between layers of tunica vaginalis

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19
Q

infant hydrocele presentation:

A

infant/toddler with hemiscrotal enlargement; volume/size waxes and wanes during day

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20
Q

Infant hydrocele etiology:

A

patent processus vaginalis (communicating hydrocele)

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21
Q

Infant hydrocele work-up:

A

clinical diagnosis; scrotal sonogram may be helpful

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22
Q

Infant hydrocele tx:

A

if persistent after one year, repair via inguinal incision

23
Q

Adult hydrocele presentation:

A

scrotal discomfort; scrotal enlargement; possible h/o trauma or infection

24
Q

adult hydrocele etiology:

A

idiopathic; post-traumatic; post-infectious

25
adult hydrocele work-up
careful physical examination; transillumination; possible scrotal sonogram
26
Adult hydrocele tx:
- Expectant management if asymptomatic - Aspiration/sclerosis associated with recurrence - Scrotal excision (hydrocelectomy)
27
Varicocele:
congestion of veins around testis
28
varicocele epidemiology:
age 15-30, rarely over 40
29
varicocele etiology:
reflects valvular anomaly exacerbated (or caused?) by gonadal venous anatomy; rare malignant etiology (consider if right-sided, or in man > 40 years)
30
varicocele presentation:
asymptomatic; dull ache; infertility; scrotal enlargement; majority on left
31
Varicocele work-up:
Clinical diagnosis; “bag of worms” due to dilatation of veins in pampiniform plexus; examine both standing and supine; generally no need for imaging; ?SA
32
varicocele tx:
varicocelectomy; embolization; 2/3 surgically treated have fertility improvement
33
Testicular torsion:
twisting of spermatic cord causing ischemia of testis
34
testicular torsion epi:
bimodal distribution | Neonatal (extravaginal) v. pubertal (intravaginal)
35
testicular torsion etiology:
anatomic predisposition (Bell-clapper deformity; cryptorchidism); trauma; sex
36
testicular torsion presentation:
Sudden severe onset unilateral scrotal pain; nausea/emesis; abdominal pain; symptoms may be intermittent (intermittent torsion)
37
testicular torsion work-up:
Difficult exam; high-riding testis; ?negative cremasteric reflex on affected side; scrotal edema and tenderness; pain unrelieved by scrotal elevation Sonogram often equivocal or may be misleading, could delay treatment High index of suspicion
38
testicular torsion tx:
Scrotal exploration, with untwisting of cord and orchidopexy; ?contralateral orchidopexy High salvage rate if treated within 6 hours
39
Epididymitis:
inflammation or infection of epididymis
40
epididymitis etiology:
-Ascending infection from urethra, prostate, bladder <35 years - C. trachomatis, N. gonorrhoeae >35years - E.coli -Surgery (vasectomy) -Other trauma
41
epididymitis presentation:
- scrotal pain - scrotal enlargement - fever
42
epididymitis work-up:
Good history and exam; UA C&S; ?penile swab/probe for STI, ?scrotal sonogram
43
epididymitis tx:
- Antibiotics (empiric by age, i.e. doxycycline or ciprofloxacin) - Palliatives (scrotal support, NSAIDs, ice, narcotics)
44
orchitis:
acute inflammatory reaction of testis secondary to infection
45
orchitis etiology:
Most common – viral mumps infection in children Bacterial orchitis - most commonly associated with epididymitis in sexually active males and men >50 with BPH C. trachomatis, N. gonorrhoeae, E. coli
46
orchitis presentation:
- Scrotal pain (mild-severe) and swelling - Exam can reveal impressive induration and edema - Overlying skin frequently thickened - Testicle won’t move freely in the scrotum, seems “stuck”
47
orchitis work-up:
Good history and exam; UA C&S; ?penile swab/probe for STI, ?scrotal sonogram
48
orchitis tx:
- Viral (mumps orchitis) - no medications; may lead to infertility - Bacterial - treat suspected organism, exclude/address abscess
49
testis cancer histology:
- Germ cell (95%): - -Seminoma - -Non-seminoma (NSGCT) - -Mixed (managed as NSGCT) - Non germ cell (5%) - Rare secondary tumors (lymphoma, leukemia)
50
testis cancer presentation:
painless testicular mass Usually incidental by partner or after trauma Cough or dyspnea secondary to lung metastases GI symptoms secondary to retroperitoneal metastases Gynecomastia
51
testis ca work-up:
Scrotal sonogram Tumor markers (AFP, beta-hCG, LDH); CT to assess the lymph nodes of retroperitoneum Radical inguinal orchiectomy
52
testis ca tx:
guided by histology (seminoma v. NSGCT) and staging (markers + imaging) Surveillance Adjuvant chemotherapy Adjuvant radiotherapy Retroperitoneal lymph node dissection (RPLND)
53
testis ca prognosis:
Cure rate 90% for seminoma (all stages combined) | Cure rate approaches 100% for low-grade NSGCT