The ___________ is the main recipient of the excitatory afferents that arise from the entire cerebral cortex from the intralaminar nuclei of the thalamus. Flashcards
The ___________ is the main recipient of the excitatory afferents that arise from the entire cerebral cortex from the intralaminar nuclei of the thalamus.
A. Lentiform Nucleus
B. Striatum
C. Globus Pallidus
D. Putamen
B. Striatum
All of the following statements about the basal ganglia are correct EXCEPT:
A. The net effect of excitation of the direct pathway is to inhibit cortex.
B. The basal ganglia have both motor and cognitive function.
C. The subthalamic nucleus is the origin of the only purely excitatory pathway within the basal ganglia intrinsic circuitry.
D. Parkinsons disease results from damage to the basal ganglia.
A. The net effect of excitation of the direct pathway is to inhibit cortex.
A 78 year old man is brought to emergency department and upon examination, the man revealed an uncontrollable flailing movements of his left arm. Which of the following structures is most likely involved in this lesion?
A. Putamen
B. Corpus Striatum
C. Subthalamic Nucleus
D. Globus Pallidus
C. Subthalamic Nucleus
A patient presented with a severe tremor, bradykinesia, rigidity and progressive cognitive decline. He was diagnosed with a degenerative disorder and his dyskinetic symptoms were treated with L-dopa/Cabidopa. What neurotransmitter is primarily involved in this disorder?
A. Acetylcholine
B. GABA (y-aminobutyric acid)
C. Norepinephrine
D. Dopamine
D. Dopamine
The abnormal gene that causes Huntington’s disease has many repeating codon that codes for multiple extra _________ in the molecular structure of an abnormal cell protein called _________ that causes the symptoms.
A. proline; huntingtin
B. acetycholine; choreon
C. glutamate; huntingtin
D. GABA; choreon
C. glutamate; huntingtin
Arrange the correct sequence of the direct pathway in the basal ganglia:
A. Thalamus > Striatum > Globus Pallidus (external)/ Substantia Nigra (pars reticulata) > Cortex
B. Cortex > Striatum > Globus Pallidus (internal)/ Substantia Nigra (pars reticulata) > Thalamus
C. Thalamus > Striatum > Globus Pallidus (internal)/ Holguin, Genevieve Substantia Nigra (pars reticulata) > Cortex
D. Cortex > Striatum > Globus Pallidus (external)/ Substantia Nigra (pars reticulata) > Thalamus
B. Cortex > Striatum > Globus Pallidus (internal)/ Substantia Nigra (pars reticulata) > Thalamus
Arrange the correct sequence of the indirect pathway in the basal ganglia:
A. Thalamus > Striatum > Globus Pallidus (internal) > Subthalamic Nuclei > Globus Pallidus (external)/ Substantia Nigra (pars reticulata)> Cortex
B. Cortex > Striatum > Subthalamic Nuclei > > Globus Pallidus (internal)/ Substantia Nigra (pars reticulata) > Globus Pallidus (external) > Thalamus
C. Cortex > Striatum > Globus Pallidus (external) > Subthalamic Nuclei > Globus Pallidus (internal)/ Substantia Nigra (pars reticulata) > Thalamus
D. Striatum > Cortex > Globus Pallidus (external) > Subthalamic Nuclei > Globus Pallidus (extternal)/ Substantia Nigra (pars reticulata) > Thalamus
C. Cortex > Striatum > Globus Pallidus (external) > Subthalamic Nuclei > Globus Pallidus (internal)/ Substantia Nigra (pars reticulata) > Thalamus
Corpus Striatum of the basal ganglia is/ are composed of?
A. Globus Pallidus and Putamen
B. Putamen, Globus Pallidus and Subthalamic Nucleus
C. Caudate Nucleus and Putamen
D. Putamen, Globus Pallidus and Caudate Nucleus
D. Putamen, Globus Pallidus and Caudate Nucleus
Connections between the ________ and _________ use dopamine as a neurotransmitter.
A. Thalamus and Substantia Nigra
B. Globus Pallidus and Substantia Nigra
C. Cortex and Substantia Nigra
D. Striatum and Substantia Nigra
D. Striatum and Substantia Nigra
A snake – like or writhing movements of the hand, face and arm results from the lesions of the ________.
A. Subthalamic Nucleus of Luys
B. Globus Pallidus
C. Corpus Striatum
D. Caudate Nucleus
B. Globus Pallidus
Extrafusal skeletal muscle fibers are innervated by the_______.
A. Anterior motor neuron
B. Gamma motor neuron
C. Alpha motor neuron
D. Interneuron
C. Alpha motor neuron
Alpha motor neuron cell bodies are topographically arranged within the____.
A. Anterior dorsal horn
B. Anterior ventral horn
C. Posterior dorsal horn
D. Posterior ventral horn
B. Anterior ventral horn
Muscle spindle helps in regulation of muscle action because of its composition of the following:___.
A. Sensory: Group Ia afferent nerve fibers, which innervates nuclear bag fibers; and group II afferent nerve fibers which innervates nuclear chain fibers.
B. Sensory: Group IIa afferent nerve fibers, which innervates nuclear bag fibers; and group I afferent nerve fibers which innervates nuclear chain fibers.
C. Encapsulated extrafusal muscle fibers.
D. Encapsulated tendon within the muscle
A. Sensory: Group Ia afferent nerve fibers, which innervates nuclear bag fibers; and group II afferent nerve fibers which innervates nuclear chain fibers.
What is the action of the Golgi tendon organ in regulation to muscle action?
A. Mechanoreceptor present within the tendon that responds to the change in length.
B. Mechanoreceptor present within the tendon that responds to the degree of tension that relays it by the afferent fibers (group IIb)
C. Mechanoreceptor present within the tendon that responds to the degree of stretch.
D. Mechanoreceptor present within the tendon that responds to the degree of tension that relays it by the afferent fibers (group Ib)
A. Mechanoreceptor present within the tendon that responds to the change in length.
Composed of two or more synapses between a sensory and motor neurons is a ____?
A. Polysynaptic reflex
B. Monosynaptic reflex
C. Single-synaptic reflex
D. Bi-synaptic reflex
A. Polysynaptic reflex
Example of a monosynaptic reflex is____?
A. Inverse myotactic reflex
B. Myotactic reflex
C. Clasp knife reflex
D. Flexor withdrawal reflex
B. Myotactic reflex
A monosynaptic reflex that is elicited in a neurologic exam by tapping the tendon in areas such as the knee.
A. DTR
B. GTR
C. Reflex arc
D.Inverse myotactic
A. DTR
A polysynaptic reflex that occurs as a response to a painful stimuli.
A. Extensor withdrawal reflex
B. Flexor withdrawal reflex
C. Crossed extensor reflex
D. Crossed flexor reflex
B. Flexor withdrawal reflex
A kid running barefooted accidentally stepped on a thumbtack, as the kid felt the painful stimulus he raises the affected foot, without thinking, he stabilizes his position with the unaffected side. After the accident he bent down and extended his limbs to check for his foot, then afterwards continued crossing the road.
Crossed extensor reflex in this situation is_____
A. Kid raises the affected foot creating a withdrawal response.
B. Kid stabilizes his position with the unaffected side.
C. Kid extended his limbs to check for his foot.
D. Kid stabilizes his position with the affected side.
B. Kid stabilizes his position with the unaffected side.
A negative feedback mechanism that monitors muscle tension. It has two synapses that relaxes the muscles when it detects an excess in tension. It is called?
A. Deep Tendon Reflex
B. Flexor withdrawal reflex
C. Crossed extensor reflex
D. Inverse Myotactic Reflex or Golgi Tendon Reflex
D. Inverse Myotactic Reflex or Golgi Tendon Reflex
Which of the following is incorrectly paired?
A. Pontine (Medial) reticulospinal tract : Pontine reticular formation
B. Rubrospinal tract : Red nucleus
C. Tectospinal tract : Superior colliculus
D. Medullary (Lateral) reticulospinal tract : Deiter’s nucleus
D. Medullary (Lateral) reticulospinal tract : Deiter’s nucleus
Trace the tectospinal tract stimulation.
A. Red nucleus à Intermediate gray area à Inhibit flexors and extensors
B. Superior colliculus à Cervical spinal cord à Decussate before entry to spinal cord à Control of neck muscles
C. Red nucleus à Cervical spinal cord à Decussate before entry to spinal cord à Control of neck muscles
D. Superior colliculus à Intermediate gray area à Inhibit flexors and extensors
B. . Superior colliculus à Cervical spinal cord à Decussate before entry to spinal cord à Control of neck muscles
Trace the vestibulospinal tract stimulation.
A. Deiter’s nucleus à Ipsilateral motoneurons and interneurons à Stimulation of extensors and inhibition of flexors
B. Deiter’s nucleus à Ventromedial spinal cord à Stimulatory effect on both extensors and flexors w/ predominant effect on extensors
C. Deiter’s nucleus à Cervical spinal cord à Stimulation of flexors and inhibition of extensors
D. Deiter’s nucleus à Interneurons in the lateral spinal cord à Stimulatory effect on both extensors and flexors w/ predominant effect on extensors
A. Deiter’s nucleus à Ipsilateral motoneurons and interneurons à Stimulation of extensors and inhibition of flexors
Reticulospinal tract is important in maintenance of certain postures and in __________________.
A. Erect posture
B. Startle reaction
C. Eye movements
D. Control of neck muscles
B . Startle reaction
Pontine reticulospinal tract produce _________ effect on both extensors and flexors, with predominant effect on ______________.
A. inhibitory, flexors
B. stimulatory, flexors
C. inhibitory, extensors
D. stimulatory, extensors
D. stimulatory, extensors
All of the ff. refer to decerebrate rigidity except:
A. Lesions above the red nucleus
B. Involuntary extension of the upper extremities in response to external stimuli
C. Lesions above the Pontine Reticular formation but below the midbrain
D. Lesions above the lateral vestibular nucleus
A. Lesions above the red nucleus
All of the ff. are true w/ Rubrospinal Tract except:
A.Receive afferent info from cortex, cerebellum and basal ganglia
B. Most important extrapyramidal tract
C. Lesions are always ipsilateral
D. Voluntary movements are impaired w/ lesions
C. Lesions are always ipsilateral
Trace the Medullary Reticulospinal Tract stimulation
A. Medullary reticular formationà Intermediate gray à Inhibit flexors and extensors,
B. Medullary reticular formation à Deiter’s nucleus à Inhibit flexors and extensors
C. Medullary reticular formation à Superior colliculus à Inhibit flexors and extensors
D. Medullary reticular formation à Centro-medial spinal cord à Inhibit flexors and extensors
A. Medullary reticular formationà Intermediate gray à Inhibit flexors and extensors
Decorticate rigidity manifests as the following except:
A. Arms flexed
B. Hands are flexed and clenched into fists
C. Legs flexed
D. Feet turned inward
C. Legs flexed
All of the following are functions of Vestibulospinal Tract, except:
A. Stimulation of extensors and inhibition of flexors
B. Selective control of excitatory signals to the different antigravity nucleus
C. Making adjustments in response to signals from the vestibular apparatus
D. Control of neck muscles
D. Control of neck muscles
These zones do not have topographical representation and concerned in the overall planning of the sequential motor movements with the cerebral cortex
A. Vermis
B.Lateral zone of cerebellar hemispheres
C. Intermediate zone of cerebellar hemispheres
D. Floccunodular lobe
B. Lateral zone of cerebellar hemispheres
The vermis part of the cerebellum is concerned with ______ of the body while intermediate zones of cerebellar hemispheres is concerned with _____ of the body.
A. Limbs and facial region, axial portion
B. Both axial portion of the body
C. Axial portion, limbs and facial regions
D. Both limbs and facial regions of the body
C. Axial portion, limbs and facial regions
Which of the following parts has the most cerebellar control for muscle movements of hips, neck, axial body and hips?
A. Anterior lobe
B. Posterior lobe
C. Vermis
D. Flocculonodular node
C. Vermis
Which of the following parts is the oldest of all portions of the cerebellum and it developed along with the vestibular system in controlling body equilibrium?
A. Lareral Zone
B. Anterior Lobe
C. Intermediate zone
D. Flocculonodular lobe
D. Flocculonodular lobe
The signals transmitted in the dorsal spinocerebellar tract come mainly from ______.
A. Golgi tendon organs, large tactile receptors of the skin and joint receptors
B. Pain receptors
C. Thermoreceptors
D. Vibration receptors
A. Golgi tendon organs, large tactile receptors of the skin and joint receptors
This pathway plays an important role in helping coordinate sequential motor activities initiated by the cerebral cortex.
A. Vermis —> Fastigial Nuclei —> Medullary and Pontine regions of the brain stem
B. Lateral zones of the cerebellar hemispheres—> Dentate nucleus—> Ventrolateral and vetroanterior nuclei of thalamus
C. Intermediatezone of cerebellar hemispheres—> interposed nucleus—> nuclei of the thalamus—> basal ganglia
D. basal ganglia—> thalamus—> interposed nucleus
B. Lateral zones of the cerebellar hemispheres—> Dentate nucleus—> Ventrolateral and vetroanterior nuclei of thalamus
This cells are always inhibitory with GABA as a neurotransmitter.
A. Granule cells
B. Stellate Cells
C. Purkinje cells
D. Basket cells
C. Purkinje cells
These cells receive excitatory input from mossy fibers which use glutamate as a neurotransmitter. A. Granule cells
B. Stellate Cells
C. Purkinje cells
D. Basket cells
A. Granule cells
Which of the following cerebellar interneurons is not inhibitory?
A. Granule cells
B. Stellate Cells
C. Basket cells
D. Golgi II cells
A. Granule cells
Dysarthia refers to which of the following?
A. Unsteady oscillations of the head or trunk
B. Jerkiness of eye movement
C. Slowing and slurring of speech
D. Volume of voice varies from low to high, from peak to peak
C. Slowing and slurring of speech
It is a result of the loss of cerebellar facilitation of the motor cortex and brain stem motor nuclei.
A. Chorea
B. Athetosis
C. Hypotonia
D. Hemiballismus
C. Hypotonia
When the motor control system fails to predict where the different parts of the body will be at a given time, it loses perception of the parts during rapid motor movements therefor Inability to perform rapid alternating movements manifest which is called?
A. Dysdiadochokinesia
B. Athetosis
C. Dysarthia
D. Hemiballismus
A. Dysdiadochokinesia
A person can predict from the changing visual scene how rapidly he or she is approaching an object. The nervous system uses the cerebellum to coordinate motor control functions at which of the three levels?
A. Spinocerebellum
B. Cerebrocerebellum
C. Vestibulocerebellum
D. Archicerebellum
B. Cerebrocerebellum
The movements ordinarily overshoot their intended mark; then the conscious portion of the brain overcompensates in the opposite direction for the succeeding compensatory movement. This effect is called?
A. Dysrhythmia
B. Dysarthia
C. Dysdiadochokinesia
D. Dysmetria
D. Dysmetria
A patient was asked to touch the heel of his foot to his opposite knee and then to drag his heel in a straight line all down the front of his sheen and back up again. What kind of cerebellar dysfunction is being tested?
A. Dysrhythmia
B. Dysarthia
C. Dysdiadochokinesia
D. Dysmetria
D. Dysmetria
Overall, muscles will receive fibers from all of the following except?
A. Corticospinal tract
B. Extrapyramidal tract
C. Cerebellar tract
D. Spinothalamic tract
A. Corticospinal tract
A cerebellar syndrome that involves the flocculonodular and posterior lobes. With little or no limb ataxia.
A. Anterior (Rostral) Vermis Syndrome
B. Posterior (Caudal) Vermis Syndrome
C. Cerebellar Hemisphere Syndrome
D. Pancerebellar Syndrome
B. Posterior (Caudal) Vermis Syndrome
Dysmetria and ataxia can also result from lesions in the________ because feedback information from the moving parts of the body to the cerebellum is essential for cerebellar timing of movement termination.
A. Spinocerebellar tract
B. Corticospinal tract
C. Spinothalamic tract
D. Pyramidal tract
A. Spinocerebellar tract
It uses GABA as its Neurotransmitter.
A. Stellate cells
B. Basket cells
C. Purkinje cells
D. Granule cells
C. Purkinje cells
It is the smallest and most numerous neuron in the brain
A. Stellate cells
B. Basket cells
C. Purkinje cells
D. Granule cells
D. Granule cells
To cause serious and continuing dysfunction of the cerebellum, the cerebellar lesion usually must involve one or more of the deep cerebellar nuclei except?
A. Dentate nuclei
B. Interposed nuclei
C. Fastigial nuclei
D. Red nuclei
D. Red nuclei
Brodmann Area 4 located in the precentral gyrus is responsible for ____?
A. Execution of movement
B. Hearing and Balance
C. Generating plan for movement
D. Conjugate eye movement
A. Execution of movement
A special class of neurons called _____ becomes active when a person performs a specific motor task or when he or she observes the same task performed by others.
A. Mirror Neuron
B. Axon Hillock
C. Alpha Motor Neuron
D. Gamma Motor Neuron
A. Mirror Neuron
Stimulation frequently leads to bilateral grasping movements of both hands simultaneously; these movements are essentials of the hand functions required for climbing. What specialized area of the cerebellar cortex for motor control is used?
A. Pre motor Area
B. Motor Area
C. Supplementary Area
D. Frontal Lobe of the Cerebellum
C. Supplementary Area
The corticospinal tract decussates at what level?
A. Substansia Gelatinosa
B. Cervicomedullary Junction
C. Dorsal Root Ganglion
D. Thalamus
B. Cervicomedullary Junction
Conveys nerve impulses from the motor cortex to the skeletal muscles of the head and neck.
A. Corticospinal Tract
B. Corticobulbar Tract
C. Spinothalamic Tract
D. Spinocerebellar Tract
B. Corticobulbar Tract
Motor neurons that originate in the motor region of the cerebral cortex or brainstem.
A. Uppermotor Neuron
B. Lower Motot Neuron
C. Mirror Nueron
D. Alpha Motor Neuron
A. Uppermotor Neuron
Motor neurons connecting the brainstem and spinal cord to muscle fiber.
A. Uppermotor Neuron
B. Lower Motor Neuron
C. Mirror Nueron
D. Alpha Motor Neuron
B. Lower Motor Neuron
A lesion at the upper motor neuron will manifest _____?
A. Increase muscle tone, Spastic paralysis, Hyperreflexia, (+) clonus with atrophy of disuse, (+) Babinski
B. Increase muscle tone, flaccid paralysis, Hyperreflexia, (+) clonus with atrophy of disuse, (+) Babinski
C. Decrease muscle tone, Spastic paralysis, Hyperreflexia, (+) clonus with atrophy of disuse, (+) Babinski
D. Increase muscle tone, Flaccid paralysis, Hyperreflexia, (+) clonus with atrophy of disuse
A. Increase muscle tone, Spastic paralysis, Hyperreflexia, (+) clonus with atrophy of disuse, (+) Babinski
A lesion at the lower motor neuron will manifest _____?
A. Increase muscle tone, Spastic paralysis, Hyperreflexia, (-) clonus with atrophy of denervation, (+) fasciculation
B. Decrease muscle tone, Flaccid paralysis, Hyporeflexia, (-) clonus with atrophy of denervation, (+) fasciculation
C. Decrease muscle tone, Spastic paralysis, Hyperreflexia, (+) clonus with atrophy of denervation, (+) fasciculation
D. Decrease muscle tone, Spastic paralysis, Hyperreflexia, (+) clonus with atrophy of disuse
B. Decrease muscle tone, Flaccid paralysis, Hyporeflexia, (-) clonus with atrophy of denervation, (+) fasciculation
When does a person experience desynchronosis?
A. When the person cannot be awakened easily.
B. There is alteration of the day-night cycle when the person travels across time zones.
C.Person is difficult to arouse.
D.Person is experiencing irregular muscle movements.
B. There is alteration of the day-night cycle when the person travels across time zones.
Jenny, 31 years old, flight stewardess travels from Manila to Europe. When it is night time in Europe, she’s having a hard time falling asleep. Her body and mind is wide awake. What seems to be Jenny’s condition?
A. Slow sleep
B. NON-REM sleep
C. Paradoxical Sleep
D. Desynchronized sleep
D.Desynchronized sleep
Beta wave activity dominates:
A.In resting individuals with their eyes closed.
B.In infants experiencing deep sleep.
C.In adults during emotional stress.
D. In an awake, aroused individual.
D. In an awake, aroused individual.
A type of wave which indicate that you are awake and your eyes are open in the light.
A.Alpha waves
B.Beta waves
C.Theta waves
D.Delta waves
B. Beta waves
This measures the electrical activity of the brain. This can also use for diagnostic applications for epilepsy, coma and brain death.
A. MRI
B. CT Scan
C.EEG
D.ECG
C.EEG
Beta wave is an EEG wave that is recorded from what region in the brain?
A.Occipital and frontal
B.Occipital and parietal
C.Parietal and frontal
D.Frontal and temporal
C. Parietal and frontal
It is the inability of a person to obtain any amount of quality sleep needed to function during the day.
A.Narcolepsy
B.Cataplexy
C.Somnam bulism
D.Insomnia
D. Insomnia
When a person is awake, but the person has a decreased level of attention, what type of EEG rhythm will be observed?
A.Beta waves
B.Theta waves
C.Alpha waves
D.Delta waves
C. Alpha waves
A seizure disorder that has no known cause happens when there is a decrease in sodium levels in the blood.
A.Coma
B.Tonic seizure
C.Epilepsy
D.Aphasia
C.Epilepsy
This type of EEG wave is associated with brain disorders and degenerative brain state.
A.Theta waves
B.Beta waves
C.Gamma waves
D.UV waves
A. Theta waves
What type of EEG rhythm is produced by any form of sensory stimulation or mental concentration?
A.Theta rhythm
B.Beta rhythm
C.Gamma rhythm
D.Alpha rhythm
B. Beta rhythm
Quiet wakefulness is associated with what EEG rhythm?
A.Alpha rhythm
B.Beta rhythm
C.Gamma rhythm
D.Theta rhythm
A. Alpha rhythm
Which among the components of the limbic system when stimulated evokes rage, passivity, and excessive sexual drive?
A..Hippocampus
B.Amygdala
C.Hypothalamus
C.Thalamus
A. Hippocampus
The hippocampus is associated with mamillary bodies via what structure?
A Pineal gland
B Diencephalon
C Corpus callosum
D Fornix
D. Fornix
Insomnia or restlessness is an effect of a lesion in what area of the limbic cortex?
A Lateral posterior frontal cortex
B Bilateral posterior orbitofrontal cortex
C Posterior frontal cortex
D Lateral temporal cortex
B. Bilateral posterior orbitofrontal cortex
A pathway in limbic system that makes you link other experiences, memories and emotions when encountered a certain sensory stimuli.
A Somatosensory pathway
B Papez circuit
C Autonomic pathway
D Auditory pathway
B. Papez circuit
Lesion in this area of the limbic cortex will cause extreme rage reaction.
A Bilateral posterior cingulated subcallosal gyri
B Bilateral anterior temporal cortex
C Bilateral posterior orbitofrontal cortex
D Bilateral anterior cingulated subcallosal gyri
D. Bilateral anterior cingulated subcallosal gyri
Kluver-Bucy syndrome results from a lesion in the Amygdala which manifest hyperpolarity, loss of fear, decreased aggressiveness and eating behavior. The lesion is located in the _____________
A Bilateral posterior temporal cortex
B Bilateral anterior temporal cortex
C Bilateral posterior orbitofrontal cortex
D Bilateral anterior corpus callosum
B. Bilateral anterior temporal cortex
Hypothalamus controls the set-point of human _________________.
A Blood pressure
B Milk ejection
C Body temperature
D Heart rate
C. Body temperature
Increased general activity leading to rage and aggregation is cause by what part of the hypothalamus?
A Anterior hypothalamus
B Posterior hypothalamus
C Lateral hypothalamus
D Both anterior and posterior hypothalamus
C. Lateral hypothalamus