Thalamus and Hypothalamus Flashcards

1
Q

Where is the thalamus found within the brain?

A

It is right in the middle the brain just under the posterior half of the corpus callosum

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2
Q

What separates the two halves of the thalamus?

A

3rd ventricle

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3
Q

Diencephalon consists of

A

Thalamus, subthalamic nucleus–parkinsons- deep brain stimulation, hypothalamus

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4
Q

Thalamus in relation to the lateral ventricle

A

ventral and inferior

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5
Q

Thalamus function

A

key relay centre to cortical sensory areas

-enhances and restricts signals

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6
Q

Only sensory function thalamus isn’t involved in

A

Olfactory

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7
Q

Describe the somatosensory pathway

A

touch and proprioception- cell bodies are located in dorsal root ganglia

primary sensory neuron from skin to dorsal column nuclei -gracilis nucleus/ cuneate nucleus

secondary neuron from dorsal column nuclei to thalamus - secondary neuron where crossing over occurs

Thalamus:- posterior lateral nucleus of thalamus –> processes touch and proprioception

tertiary nueorn from thalamus to primary somatosensory cortex

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8
Q

Where is primary sensory cortex located

A

post central gyrus

- behind central sulcus of parietal lobe

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9
Q

Apart from discrete nuclei you also have

A

intralaminar nuclei

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10
Q

Intralaminar nuclei project to

A

various medial temporal lobe structure

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11
Q

medial temporal lobe structures and function of these structures

A

Amygdala: fear, anxiety, emotions
Hippocampus: memory
Basal ganglia: movement– parkinsons- shaky hands

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12
Q

Neurons in intralaminar nuclei are mostyle

A

Glutamatergic neurons – excitatory

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13
Q

conditions apart from parkinsons associated with the intralaminar nuclei

A

PSP– progressive supra nuclear palsy

–> problems with walking and balance

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14
Q

Reticular nucleus found

A

outer covering of thalamus

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15
Q

Majority of reticular nucleus type

A

GABAergic–> inhibitory

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16
Q

Reticular nucleus function and how

A

internal regulation of thalamus

  • connect with local NOT distal thalamic nuclei (local circ)
  • Receive inputs from collaterals of their axons form thalamic nuclei
17
Q

Reticular formation– what and function

A

set of interconnected pathways in the brainstem

Send ascending projections to forebrain nuclei (to intralaminar retiular nuclei), Ascending Reticular Activating System – ARAS

Involved in consciousness and arousal
-increased activity of ARAS= increased wakefulness.

18
Q

Hypothalamus directly connected to

A

p.g – neuroendocrine functions

19
Q

Hypothalamus in relation to 3rd ventricle

A

are the walls and floor of the 3rd ventricle

20
Q

Hypothalamus is divided by

What is the hypothalamus

A

divided by the 3rd ventricle

Collection of individual nuclei with distinct functions

21
Q

Connection to other nuclei by hypothalamus

A

ipsilateral

22
Q

Which nucleus in hypothalamus can send projections to endocrine and ANS systems ?

A
paraventricular nucleus (has MAGNOCELLULAR and PARVOCELLULAR neurons) - involved in feeding behaviour
slide 27
23
Q

function of hypothalamus

A

4 Fs of life

Fighting, fleeing, feeding, fucking

24
Q

Structure below hypothalamus

A

Pituitary gland

25
Q

what structure located above optic chiasm

A

supraoptic nuclei

26
Q

Paraventricular system also involved in

A

feeding– GABAergic stim of LH neuron in PV nucleus results in feeding

Hyothalamus-feeding– Expression of GLP-1r in hypothalamus – inhibit eating

27
Q

Which nucleus is involved in the circadian rhythm?

A

Suprachiasmatic nucleus- above optic chiasm. it is part of the hypothalamus

28
Q

Hypothalamus

A
  1. Regulate ANS: Direct connections with autonomic nervous system, neurons from paraventricular nucleus of hypothalamus can go all the way down to the spinal cord to synapse with a preganglionic neuron that then leaves the spinal cord IMPORTANTTTTT

2.Connection with endocrine system
3. Control of behaviour ie 4 F’s of life
Fighting
Fleeing
Feeding
Fucking

29
Q

3 autonomic control examples

A

kidneys, vasculatur heart

30
Q

How does suprachiasmatic nucleus control circadian rhythm

and other function

A

connected to pineal gland–> release of melatonin

autonomic outflow through connections to paraventricular nucleus.

31
Q

3 characterstics of parkinsons

A

tremor, akinesia, sleep disturbances