Thalamus Flashcards

1
Q

What does Diencephalon give rise to

A

Thalamus, Subthalamus, Hypothalamus

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2
Q

describe structure of thalamus

A

Split down the middle by third ventricle

Ventral to the lateral ventricles

Organised into discrete nuclei

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3
Q

describe functions of thalamus

A

It’s a relay centre between the cerebral cortex and rest of CNS – two way connection

Thalamus also integrates and modifies info as it passes through

Nuclei in thalmus for virtually every functional system

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4
Q

which functional system does the thalamus not have nuclei for

A

olfaction (smell)

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5
Q

Name 2 thalmic nuclei whcih form RAS

A

Intralaminar Nuclei

Reticular nucleus

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6
Q

Describe function of Intralaminar nuclei (and neuron type)

A

Project to various medial temporal lobe structures

Mostly Glutamatergic neurons - excitatory

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7
Q

which structures do intralaminar nuclei project to

A

Amygdala = emotions, fear, anxiety

Hippocampus = memory

Basal ganglia = movement

(all in temporal lobe)

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8
Q

Describe function of reticular nucleus (and neuron type)

A

forms outer covering of the thalamus

Influences flow of information through the other nuclei to the cortex

mainly GABAergic – inhibitory

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9
Q

What is distinguishes reticular nucleus from other nuclei

A

no distal connections just intrathalamic connections

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10
Q

What is function of RAS

A

(Reticular activating system)

RAS is the system that maintains consciousness

Intralaminar and Reticular nuclei offer direct and indirect way of controlling activity of nucleus

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11
Q

what is ascending reticular activating

A

Reticular formation projects up to the thalamus

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12
Q

The greater the activity through RF the…….

A

more stimulated the cortex becomes – translates into consciousness/awareness

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13
Q

what is reticular formation

A

set of interconnected pathways in brainstem

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14
Q

where are inputs from ARAS recieved

A

Both intralaminar and reticular nucleus

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15
Q

Hypothalamus structure

A

Lies below thalamus – divided down the middle
by 3rd ventricle

Collection of individual nuclei with distinct functions

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16
Q

Hypothalamus – Function

A

Direct connections with ANS

Connections with the endocrine system e.g. hypothalamic-pituitary axis

Paraventricular nucleus (feeding behaviour)

Suprachiasmatic nucleus (regulation of circadian rhythm)

17
Q

where does PVN send projections

A

Paraventricular nucleus sends projections to ANS and posterior pituitary gland

18
Q

where is Suprachiasmatic nucleus

A

just above optic chiasm

19
Q

how does SCN work

A

influences hormone secretion e.g ACTH to regulate circadian rhythm

20
Q

what would PVN lesion cause

A

hyperphagia and weight gain

21
Q

what would SCN lesion cause

A

sleep disturbance (cause disrupted sleep cycle)

This is symptom of Schizophrenia

22
Q

what is function of hypothalamus

A

Involved in 4 F’s:

Fighting
Fleeing
Feeding
Mating