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Anesthesia Pharmacology > Texas Wesleyan Drug Reference Dosages > Flashcards

Texas Wesleyan Drug Reference Dosages Flashcards

1
Q

Diazepam (Valium)
Dose - IV & PO
Onset
Duration

Benzodiazepine

A

Dose:
IV: 0.1 mg/kg;
PO: 0.2 mg/kg
Onset:
1-5 mins
Duration:
2-6hrs

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2
Q

Lorazepam (Ativan)
Dose
Onset
Duration

Benzodiazepine

A

Dose:
IV: 0.04 mg/kg
PACU: 1-4 mg
Onset:
1-5 min
Duration:
6-10hrs

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3
Q

Midazolam (Versed)
Dose
Onset
Duration

Benzodiazepine

A

Dose:
1-5 mg
Onset:
1-5 min
Duration:
15-80 min (1-2 hours)

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4
Q

Flumazenil (Romazicon)
Dose
Onset
Duration

Benzodiazepine Reversal

A

Dose:
0.2 mg followed by 0.1 mg q min until 1 mg
MAX is 3 mg
Onset:
1-5 min
Duration:
30-60 min

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5
Q

Droperidol (Inapsine)
Dose
Onset
Duration

Antiemetic - Dopamine (D2) Antagonist

A

Dose:
IV: 0.625-1.25 mg
Onset:
1-5 min
Duration:
2-3 hrs

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6
Q

Promethazine (Phenergan)
Dose
Onset
Duration

Antiemetic - Histamine (H1) & Dopamine (D1) Antagonist

A

Dose:
IV: 6.25-25 mg
Onset:
1-5 min
Duration:
4-6 hrs

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7
Q

Ondansetron (Zofran)
Dose
Onset
Duration

Antiemetic - Serotonin (5HT3) Antagonist

A

Dose:
IV: 4 mg
Onset:
10 min
Duration:
4-9 hrs

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8
Q

Dexamethasone (Decadron)
Dose
Onset
Duration

Antiemetic - Corticosteroid

A

Dose:
IV: 4 mg
Onset:
10-30 min
Lecture said delayed onset of 2 hrs
Duration:
2-10 hrs

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9
Q

Metoclopramide (Reglan)
Dose
Onset
Duration

Antiemetic - Dopamine (D1) Antagonist

A

Dose:
IV: 10-20 mg
Onset:
10 min
Duration:
2 hrs

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10
Q

Scopolamine (Scopace & Maldemar)
Dose
Onset
Duration

Antiemetic - Anticholinergic (M1-ACh)

A

Dose:
140 mcg initially followed by 1.5 mg slowly over time
Onset:
2-4hrs
Duration:
72hrs

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11
Q

Propofol (Diprivan)
Antiemetic Dose

Antiemetic - GABA Agonist

A

Dose:
IV: 10-20 mg followed by 10mcg/kg/min PRN

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12
Q

Propofol (Diprivan)
Induction Dose
Onset
Duration

Induction Agent - GABA Agonist

A

Dose:
1.5-2.5 mg/kg
Onset:
30-60 sec
Duration:
1-8 min

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13
Q

Etomidate (Amidate)
Dose
Onset
Duration

Induction Agent - GABA Agonist

A

Dose:
IV: 0.3 mg/kg
Onset:
1 min
Duration:
3-5 min

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14
Q

Ketamine (Ketalar)
Induction, Analgesia, IM Dose
Onset
Duration

Induction Agent - NMDA Antagonist

A

Dose:
Induction: 0.5-1.5 mg/kg
Analgesia: 0.2-0.5 mg/kg
IM: 4-8 mg/kg
Onset:
1 min
Duration:
10-20 min

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15
Q

Midazolam
Induction Dose
Onset
Duration

Induction Agent - Benzodiazepine

A

Dose:
IV: 0.1-0.2 mg/kg
w/ fentanyl 50-100 mcg first
Onset:
30-60 sec
Duration:
5-10 min

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16
Q

Morphine (MS-Contin)
Dose
Onset
Duration

Opioid Agonist - Mu1 & Mu2

A

Dose:
Intra op IV: 1-10 mg
Post op IV: 5-20 mg
Onset:
10-20 min
Duration:
4-5 hr

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17
Q

Fentanyl (Sublimaze)
Dose
Onset
Duration

Opioid Agonist - Mu1 & Mu2

A

Dose:
Intra op IV: 1-3 mcg/kg
Onset:
30-60 sec
Duration:
1-1.5 hrs

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18
Q

Sufentanil (Sufenta)
Dose - IV & Infusion
Onset
Duration

Opioid Agonist - Mu1 & Mu2

A

Dose:
IV: 0.3-1 mcg/kg
Infusion: 0.5-1 mcg/kg/hr
Onset:
30-60 sec
Duration:
1-1.5 hrs

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19
Q

Remifentanil (Ultiva)
Dose - IV & Infusion
Onset
Duration

Opioid Agonist - Mu1 & Mu2

A

Dose:
Intra op 0.5-1 mcg/kg over 1 min
Infusion: 0.125-0.375 mcg/kg/min
Onset:
30-60 sec
Duration:
6- 8 min

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20
Q

Meperidine (Demerol)
Dose
Onset
Duration

Opioid Agonist - Mu1, Mu2, Kappa, Alpha2

A

Dose:
IV: 12.5 mg
Onset:
5-15 min
Duration:
2-4 hrs

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21
Q

Hydromorphone (Dilaudid)
Dose
Onset
Duration

A

Dose:
Intra op IV: 1-4 mg
Post op IV: 0.5-4 mg
Onset:
5-15 min
Duration:
2-4 hrs

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22
Q

Naloxone (Narcan)
Dose
Onset
Duration

Opioid Antagonist - Mu, Delta, Kappa

A

Dose:
40-80 mcg
Onset:
1-5 min
Duration:
30min

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23
Q

Succinylcholine (Anectine)
Dose
Onset
Duration

Depolarizing Neuromuscular Blocking Agent

A

Dose:
1-1.5 mg/kg
Onset:
30-60 sec
Duration:
5-10 min

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24
Q

Cisatricurium (Nimbex)
Dose
Onset
Duration

Non-depolarizing Neuromuscular Blocking Agent

A

Dose:
IV: 0.1mg/kg
Onset:
2-3 min
Duration:
40-75mins

25
Q

Vecuronium (Norcuron)
Dose
Onset
Duration

Non-depolarizing Neuromuscular Blocking Agent

A

Dose:
IV: 0.1mg/kg
Onset:
2-3 min
Duration:
45-90 min

26
Q

Rocuronium (Zemuron)
Dose
Onset
Duration

Non-depolarizing Neuromuscular Blocking Agent

A

Dose:
IV: 0.6-1.2 mg/kg
Onset:
2-3 (1.5) min
Duration:
35-75 min

27
Q

Pancuronium (Pavulon)
Dose
Onset
Duration

Non-depolarizing Neuromuscular Blocking Agent

A

Dose:
IV: 0.1mg/kg
Onset:
2-3 min
Duration:
60-120 min
(1-2hrs)

28
Q

Neostigmine (Bloxiverz)
Dose
Onset
Duration

Acetylcholinesterase Inhibitor

A

Dose:
IV: 40-70 mcg/kg
Onset:
5-10 min
Duration:
60 min

29
Q

Glycopyrrolate (Robinul)
Dose
Onset
Duration

Acetylcholine Antagonist

A

Dose:
IV: 0.2 mg per mg/ml of neostigmine
Onset:
1 min
Duration:
60-120 min

1 ml of robinul per 1 ml of neostigmine

30
Q

Sugammadex (Bridion)
Dose
Onset
Duration

Aminosteroid Curare Reversal - Intermolecular/Van der Walls

A

Dose:
IV: 2-16mg/kg
Onset:
1-4 min
Duration:
1.5-3 hrs

31
Q

Sevoflurane (Ultane)
MAC
Blood:Gas
Vapor Pressure

A

MAC:
1.8 %
Blood Gas:
0.69
Vapor pressure:
157 mmHg

32
Q

Isoflurane (Forane)
MAC
Blood:Gas
Vapor Pressure

A

MAC:
1.17 %
Blood:Gas:
1.46
Vapor pressure:
238 mmHg

33
Q

Desflurane (Suprane)
MAC
Blood:Gas
Vapor Pressure

A

MAC:
6.6 %
Blood:Gas:
0.42
Vapor pressure:
669 mmHg

34
Q

Nitrous Oxide (Entonox)
MAC
Blood:Gas
Vapor Pressure

A

MAC:
104 %
Blood:Gas:
0.46
Vapor pressure:
Gas

35
Q

Acetaminophen (Tylenol)
Dose
Onset
Duration

NSAID/COX 1&2 Antagonist

A

Dose:
IV: 1000 mg q4-6h
Max: 3000-4000 mg
Onset:
30-60 min
Duration:
6-8 hrs

36
Q

Ketorlac (Toradol)
Dose
Onset
Duration

NSAID - COX 1&2 Antagonist

A

Dose:
IV: 15-30 mg q6h
Max: 60-120 mg
Onset:
30 min
Duration:
4-6 hrs

37
Q

Ibuprofen (Caldor)
Dose
Onset
Duration

NSAID - COX 1&2 Antagonist

A

Dose:
IV: 200-800 mg q6h
Max: 3200 mg qd
Onset:
1-2 hrs
Duration
6 hrs

38
Q

Dexmedetomidine (Precedex)
Dose & Mixture
Onset
Duration

Alpha2 Adrenergic Agonist

A

Dose:
IV: 0.5-1 mcg/kg over 10 mins
Mixture:
200 mcg/2 ml mixed w/ NS 48 ml = 4 mcg/ml
Onset:
5-10 min
Duration:
1-4 hrs

39
Q

Lidocaine (Xylocaine)
Regional Dose
Onset
Duration

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
5 mg/kg w/o epi
7 mg/kg w/ epi
Onset:
Rapid
Duration:
60-120 min

40
Q

Prilocaine (Citanest)
Regional Dose
Onset
Duration

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
6 mg/kg w/o epi
8.5 mg/kg w/ epi
Onset:
Slow
Duration:
60-120 min

41
Q

Mepivacaine (Carbocaine)
Regional Dose
Onset
Duration

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
5mg/kg w/o epi
7 mg/kg w/ epi
Onset:
Slow
Duration:
90-180 min

42
Q

Bupivacaine (Marcaine)
Regional Dose
Onset
Duration

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
2.5 mg/kg w/o epi
2.5 mg/kg w/ epi
Onset:
Slow
Duration:
240-280 min

43
Q

Ropivacaine (Noropin)
Regional Dose
Onset
Duration

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
3mg/kg w/o epi
4 mg/kg w/ epi
Onset:
Slow
Duration:
240-280 min

44
Q

Procaine (Novocaine)
Regional Dose
Onset
Duration

Ester Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
7 mg/kg w/o epi
8.5 mg/kg w/ epi
Onset:
Slow
Duration:
45-60 min

45
Q

Chloroprocaine (Nesacaine)
Regional Dose
Onset
Duration

Ester Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
6 mg/kg w/o epi
14 mg/kg w/ epi
Onset:
Rapid
Duration:
30-45 min

46
Q

Tetracaine (Pontocaine)
Regional Dose
Onset
Duration

Ester Local Anesthetic - Voltage Gated Na Channel Blocker

A

Max Dose:
3mg/kg w/o epi
3 mg/kg w/ epi
Onset:
Slow
Duration:
60-180 min

47
Q

Bupivacaine (Marcaine)
Epidural Dose
Spinal Dose

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Epidural:
0.0625-0.125%
Spinal:
1.25-2.5 ml

48
Q

Ropivacaine (Naropin)
Epidural Dose
Spinal Dose

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Epidural Dose:
0.08-0.2%
Spinal Dose:
2.5-4.5 ml

0.08-0.2% = 0.8-2 mg

49
Q

Lidocaine w/ Epinephrine
Epidural Dose

Amide Local Anesthetic - Voltage Gated Na Channel Blocker

A

Epidural Dose:
2% in 5ml bolus

2% = 20 mg

50
Q

Fentanyl (Sublimaze)
Epidural Dose
Spinal Dose

Opioid Agonist - Mu1 & Mu2

A

Epidural Dose:
50-100 mcg
Spinal Dose:
10-25 mcg

51
Q

Sufentanil (Sufenta)
Epidural Dose
Spinal Dose

Opioid Agonist - Mu1 & Mu2

A

Epidural Dose:
5-10 mcg
Spinal Dose:
1.5-5 mcg

52
Q

Morphine
Spinal Dose

Opioid Agonist - Mu1 & Mu2

A

Spinal Dose:
0.1-0.2 mg

53
Q

Ephedrine
Dose
Concentration
Onset
Duration

Indirect Sympathomimetic - Evokes NE Release

A

Dose:
IV: 5 mg
Concentration
50 mg/ml
Onset:
Rapid
Duration:
60 min

Hypotension w/ bradycardia

54
Q

Phenylephrine (Neosynephrine)
Dose
Concentration
Onset
Duration

Direct Alpha Adrenergic Agonist

A

Dose:
IV: 50-100 mcg
Concentration
10 mg/ml
Onset:
Rapid
Duration:
1 min

Hypotension w/ normal HR & tachycardia

55
Q

Labetalol (Trandate)
Dose
Concentration
Onset
Duration

Mixed Alpha1 & nonselective Beta1 & Beta2 Adrenergic Antagonist

A

Dose:
IV: 5 mg
Concentration
5 mg/ml
Onset:
5-10 min
Duration:
1-4 hrs

HTN & excessive SNS stimulation

56
Q

Esmolol (Brevibloc)
Dose
Concentration
Onset
Duration

Beta1 selective adrenergic antagonist

A

Dose:
IV: 10 mg
Concentration
10 mg/ml
Onset:
Rapid
Duration:
10-30 min

HTN, tachycardia, & excessive SNS stimulation; DOC for CEA

57
Q

Hydralazine (Apresoline)
Dose
Concentration
Onset
Duration

Direct Vasodilator - Direct-acting smooth muscle relaxant

A

Dose:
IV: 5 mg
Concentration
20 mg/ml
Onset:
Slow; peaks 1 hr
Duration:
~12 hrs

HTN

58
Q

Sphincter of Oddi
Spasm
Treatment
Drugs of Choice
&
Doses

A

Glucagon:
IV: 2 mg
Naloxone:
IV: 40 mcg
Atropine:
IV: 0.2 mg
Nalbuphine:
IV: 10 mg
NTG:
IV: 50 mcg

59
Q

Lipid Rescue
For LAST
Loading/Bolus Dose
Infusion Dose

Local Anesthetic Systemic Toxicity

A

Loading/Bolus Dose
IV: Intralipid 20% 1.5 ml/kg over 1 min
Repeat bolus up to 3 ml/kg

Infusion Dose
IV: Intralipid 20% 0.25 ml/kg/min
Increase up to 0.5 ml/kg/min for refractory hypotension

Anesthesia Pharmacology (16 decks)

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