Tetracyclines Flashcards
1
Q
Which Abx have this MOA: Interferes with bacterial 30S ribosome protein production
A
Tetracycline & Doxycycline
2
Q
When would you use Tetracycline?
A
Acne, exacerbations chronic bronchitis; part of H pylori regimen; Rickettsial infections; not used much now
3
Q
What is the SE/ADR for Tetracycline?
A
Photosensitivity, N/V/D; Discoloration of teeth & enamel hypoplasia, increased intracranial pressure; renal damage if outdated
4
Q
What is a contra-indication for Tetracycline?
A
Renal or hepatic disease, hypersensitivity,
5
Q
What are the drug-drug interactions for Tetracycline?
A
Antacids, bactericidal ABT, Vit K antagonists (incr anticoag)
6
Q
What would need to be monitored when using Tetracycline?
A
CrCl, BUN
