Tetracycline-Protein Synthesis Inhibitor

Question 1

Spectrum of Tetracycline

Answer 1

Broad-spectrum, Gram +/ Gram -, organisms other than bacteria (Malaria-protozoal), Tx of acne

Question 2

True/False Widespread resistance to tetracyclines is a major factor that effects their clinical use.

Answer 2

True

Question 3

One absorption complication from dietary practices and Tetracycline

Answer 3

Taking these drugs with diary foods decreases absorption due to formation of nonabsorbable chelates inhibiting bone formation (<8 year olds and Pregnant/Nursing Women)

Question 4

What intracellular infections is tetracycline useful for

Answer 4

Chlamydial, Rickettsial

Question 5

With anuric factor, is Tetracline-HCL better or Doxycyline?

Answer 5

Doxycycline

Question 6

What drug interaction and intestinal flora complications arrise with the use of Tetracycline?

Answer 6

Tetracycline suppresses intestinal bacteria that produces Vitamin K. Decreased levels of Vitamin K increase the risk of bleeding in patients taking oral anticoagulants by inhibiting vitamin K-dependent clotting factors.

Question 7

What common adverse effects with the use of Tetracycline do you risk?

Answer 7

Superinfection, renal toxicity, hepatotoxicity, Photosensitization