Tetanus Flashcards

1
Q

Describe clostridium tetani

A

A gram positive anaerobic rod… With a terminal round spore giving it A DRUMSTICK appearance

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2
Q

What kind of environment is required for growth of this organism

A

Low oxygen tension

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3
Q

Describe the exoticism produced

A
  1. .. Tetanospasmin.. is a?? Neurotoxin

2. .. Tetanolysin.. is a?? Oxygen labile hemolysin

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4
Q

Incubation period of tetanus

A

3 days to 3 weeks… Average- 7 days

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5
Q

Describe period of onset

A

The interval between the first symptom n the first reflex spam… The condition is fatal if?? This is less than 48 hrs

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6
Q

Tetanus neonatorum results due to

A

Contamination of cut surface of umbilical cord… The most common cause of death in such cases?? Spam of respiratory muscles

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7
Q

Post shortfall tetanus or Puerperal tetanus results due to

A

Unsterile manipulation or instrumentation during labour or abortion

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8
Q

The toxin reaches CNS by either

A
  1. .. Traveling through motor nerves

2. .. Through blood stream

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9
Q

Ultimate date of the toxin

A

It ultimately reaches Spinal CORD n gets fixed to motor cells of the auntie horn. Once fixed like this, no amount of anti tetanus serum can neutralise this

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10
Q

Most common EARLY symptom of tetanus

A

Trismus

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11
Q

Describe risus Sardonicus

A

Characteristic anxious expression due to spam of facial n use muscles

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12
Q

Opisthotonos?

A

Rigidity of muscles of neck n trunk

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13
Q

Tetanus prophylaxis?

A
  1. Formol toxoid or alum precipitated toxoid used

2. Now a days aluminium phosphate adsorbed tetanus toxoid is used

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14
Q

DTP?

A

Diphtheria, pertussis, tetanus

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15
Q

How much n where is TT injected

A

0.5 ml… IM left deltoid region

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16
Q

Passive immunization?

A

To whom it is given?? To non immunised individual at the time of injury… Done either with?? Equine ATS ( prepared from?? Horse serum) or human ATG (AKA?? Humotet)

Which one is preferred? Humotet

Why? Chances of anaphylactic reaction are less n is much more protective

17
Q

Penicillin is DASH for clostridium tetani?

A

Bacteriostatic