TEST TWO STUDY GUIDE Flashcards
What is the Genetic code for DNA
A-T, C-G
What is the Genetic code for RNA
A-U, C-G
Codons are made up of how many letters?
3`
Start codon
site where protein translation initiates (AUG).
Stop codon
marks termination of translation process (UAG, UAA, UGA).
Telemeres
Endcaps on individual strands, protect and organize chromosomes.
Transcription
DNA —> mRNA through
Initiation, Elongation, and termination. Copying genetic information.
Translation
mRNA —-> proteins. Using info on mRNA strand and constructing a protein through
Initiation, elongation, and termination.
mRNA
messenger that transcribes info, leaves nucleus, and moves to ribosomes.
rRNA
ribosomal RNA - workbench to assemble proteins (polypeptide chains)
tRNA
transport RNA - moves amino acids to ribosomes, contains anti-codons
Cell division
used for growth, repair, and maintenance.
Genes are ____ of DNA that do what?
Segments of DNA that code for a specific functional molecule (protein or RNA)
Duplicated chromosomes are composed of what?
Two sister chromatids
Why is DNA compacted?
For necessary chromosomal segregation during mitosis.
Built-in checkpoints do what in cellular division?
Allow problems to be corrected before cycle proceeds
Mitosis system steps are:
Prophase, Metaphase, Anaphase, Telophase, and Cytokinesis (PMATC)
Prophase
nucleus breaks down, chromosomes condense
Metaphase
Chromosomes line up, filaments attach to create sister chromatids
Anaphase
Sister chromatids pull apart chromosome
Telophase
New nuclear membranes form, filaments die (not needed)
Cytokinesis
Final division of the cell
Interphase
Before Mitosis, prepares cell for division. Three phases: G1, S1, and G2.
Interphase: G1 phase (first gap)
cell is getting building blocks of chromosomal DNA and accumulating energy to replicate nucleus.
Interphase: S phase (synthesis)
DNA replication that results in identical pairs of DNA molecules
Interphase: G2 phase (second gap)
replinishes energy stores, synthesizes proteins for chromosomal manipulation.
When does cancer occur?
Checkpoints break down during cell division.
What does meiosis do?
For sexual reproduction, produces four genetically unique daughter cells with half the number of chromosomes of parent cell. Specifically designed for sex cells (games like sperm or egg).
What happens in meiosis I?
Homologous chromosomes seperate
What happens in meiosis II?
Sister chromatids seperate, resulting in 4 daughter cells.
Only _____ cells are ______.
only haploid cells are gametes
The body of an organism is _____
haploid
What did Gregor Mendel do, and how did he do it?
Discovered genetic inheritance through experimentation with pea plants.
Continuous variation
different results of genes (human height)
Discontinuous variation
inherited traits (white vs. purple flowers).
Hybridization
mating two true-breeding individuals w/ different traits such as tall v. short.
F1:
F2:
P:
First, second, parental generation.
Trait
visible variation of physical appearance
Probability basics
probability a trait will occur
Allele
gene variants that arise by mutation, exist at same relative locations on homologous chromosomes
Phenotype
physical trait shown by organism
Genotype
underlying genetic makeup, visible AND non-expressed alleles.
Homozygous
2 identical alleles for a gene
Heterozygous
genotype reflects different alleles for gene
Mendel’s law of segregation
paired unit factors must segregate into equal number of gametes so that offspring can inherit either
Law of independent assortment
genes do not influence each other with regard to sorting alleles into gametes
Chromosomal Theory of inheritance
chromosomes are responsible for Mendelian inheritance
Homologous recombination
homologous chromosomes undergo reciprocal changes, “crossing over”
Nonparental Types
genetic combination are different from their parents
Parental types
descendant exhibits same allelic combination as their parents
Recombination frequency
average number of crossovers b/n two alleles
Inherited disorders occur when?
When chromosomes behave abnormally during MEIOSIS
Karyotype
number and appearance of chromosomes, shown in karyogram
Autosomes
body chromosomes, organized largest to smallest
Translocations
segment of genetic material breaks from one chromosome and reattaches to another, or different part of the same chromosome
Nondisjunction
when homologous chromosome pairs or sister chromatids fail to separate during meiosis
Monosomy
losing a chromosome
Trisomy
gaining a chromosome
X-inactivation
visible in cats, one of two X chromosomes in female’s cells is inactivated during embryonic development
Chromosome inversion
detachment and reinsertion of part of a chromosome