Test Questions

Question 1

Dihydropyridines focus on what?

Answer 1

Vascular selectivity (only work on vascular calcium channels)

Question 2

What drug is both cardiac and vascular selective?

Answer 2

Diltiazem

Question 3

Which drug is only cardiac selective?

Answer 3

Verapamil

Question 4

Contraindication of DHP

Answer 4

Acute events, like angina and no forward flow.

Question 5

What is an effect of K+ sparring diuretic? (test)

Answer 5

Blood K+ can become a little elevated, some cases its an advantage.

Question 6

(test) what are 2 main markers of diuretic function?

Answer 6

Urea and Creatine. esp serum creatine

Question 7

There is impaired glucose tolerance esp with ______

Answer 7

Thizides. Typically little more in diabetics

Question 8

(test) Diuretic resistance generally happens with _______

Answer 8

repeated doses

Question 9

(test) What 4 things does pK involve?

Answer 9

1. Absorption 2. Distribution (how it goes through the body) 3. Metabolism (How body uses/gets rid of it) 4. Elimination (How body removes completely)

Question 10

Syncope reduces what?

Answer 10

pre and afterload

Question 11

Nitrate _____ period required with long acting therapies

Answer 11

free. b/c if body is exposed to drug for long periods it builds a tolerance. Encouraged for patients

Question 12

No cGMP equals what?

Answer 12

No vasodilation

Question 13

Nitrate tolerance can also be related to free radical production explain more:

Answer 13

Reactive oxygen species (ros)- Are byproducts w/ these byproducts it can impair nitrate function.

Question 14

reactive oxygen species ROS can do what?

Answer 14

are byproducts that can impair nitrate function