Test II Flashcards
What is the main function of systemic circulation?
To deliver adequate oxygen and nutrients to the systemic tissues and remove carbon dioxide & other waste products from the systemic tissues
What conduit does the system circulation serve as?
For transport of hormones, and other substances and allows these substances to potentially act at a distant site from their production
What are the functional parts of circulation?
Systemic arteries, Arterioles & Pre-capillary sphincters, Capillaries, Venules & Systemic Veins
What is the function of system arteries in circulation?
Designed to carry blood under high pressure out to the tissue beds
What is the function of arterioles & pre-capillary sphincters?
Act as control valves to regulate flow
What is the function of capillaries?
Exchange between tissue (cells) & blood
What is the function of venules?
Collect blood from capillaries
What is the function of systemic veins?
Return blood to heart/dynamic storage.
What are the 3 basic theories of circulatory function?
1) Blood flow is proportional to metabolic demand 2) Cardiac output is controlled by local tissue flow 3) Arterial pressure control is independent of local flow or cardiac output
What is the definition of flow (F)?
The volume of blood that passes a certain point per unit of time
In the formula F = ΔP/R, flow is directly proportional to _____ and inversely proportional to _____?
ΔP [Pressure gradient (P1 - P2)]; R (resistance)
The formula F = ΔP/R is known as?
Ohm’s Law
What is the driving force of blood?
Pressure Gradient
What is proportional to flow (F)?
Pressure Gradient
The difference in pressure between two points (P1-P2) is know as?
Pressure Gradient
At any give F, the greater the drop in P in a segment or compartment, the greater the __________ to flow.
Resistance
Where does the greatest resistance to flow occur?
The pre-capillary resistance vessels (arterioles, metarterioles, precapillary sphinters)
Systemic circulation is predominately what type of circuit?
Parallel
What are the advantages of parallel circuitry?
1) independence of local flow 2) minimizes total peripheral resistance (TPR) 3) Oxygen rich blood supply to every tissue
The total vascular resistance (TVR) is equal to the sum of the total _________ resistance plus the total _________ resistance.
Pulmonic; peripheral
Internal friction of a fluid associated with the intermolecular attraction is know as?
Viscosity
Blood is a suspension with a viscosity of ______, with most of viscosity due to RBC’s
3
Plasma has a viscosity of ___?
1.5
Water is the standard with a viscosity of ____ ?
1
What increases the flexibility of RBC’s?
Fibrinogen
When velocity decreases whay increases?
Viscosity
Why does viscosity increase when velocity decreases?
Elements in the blood sticking together
Cells momentarily getting stuck at constriction points can increase __________ _____________?
Apparent viscosity
What can decrease viscosity?
Small vessel cells lining up