Test Flashcards
Most common brain tumor?
Metastasis
(Lung, breast, melanoma, renal cell)
Most common HIV/AIDS related tumor?
Lymphoma
(EBV, crosses the midline)
5 yo with solitary mass in cerebellum. What is the most likely diagnosis?
Pilocytic astrocytoma (most common)
features:
- “hairlike” processes
- frequently contain BRAF mutation
- positive for GFAP (cuz they are glial tumors)
What is the average survival of GBM s/p surgery and CRT?
12 - 14 months
What is the most common primary systemic cancer with synchronous brain mets?
lung cancer
From what cells are meningiomas derived?
Arachnoid cap (meningeal cells)
A patient presents with status epilepticus with a newly diagnosed brain tumor in the ED. What medication should be avoided?
decadron (dexamethasone)
patient presents following a motor vehicle crash. 3 days into his hospital course he develops an ICP of 45 with decreased pupil response. A head CT shows multifocal hemorrhage and sulci effacement. What is the treatment?
decompressive craniotomy
A patient has a head injury. What should be given for EARLY seizure (within first week after injury) prophylaxis? What should be given for LATE seizure prophylaxis?
EARLY = Dilantin (phenytoin)
Dilantin (phenytoin) does not help with LATE seizures
A 75 yo man presents with abnormal gain, dementia, and urinary incontinence. Lumbar puncture reveals a normal opening pressure. Imaging (MRI preferable but CT can be used) reveals enlarged ventricles. What is the diagnosis?
Normal-pressure hydrocephalus
Of the following, which is NOT a treatment for elevated ICP?
1) Hypoventilation
2) Hypertonic saline
3) Mannitol
4) Elevate head of bed
5) Drain ventricles
6) Hyperventilation
1) Hypoventilation
A 7 yo present with a 3 week history of vomiting and difficulty walking. MRI reveals a tumor of the 4th ventricle. What is the most likely diagnosis?
meduloblastoma
(although pilocytic astrocytomas are the most common, the rapid progression of symptoms suggest a meduloblastoma)
An 80 yo man fell from ground level and hit his head resulting in a subdural hemorrhage. He is currently on warfarin with an INR of 2.5. Which of the following is not a reversal agent?
1) Vitamin A
2) FFP
3) Prothrombin
4) Vitamin K
5) Cessation of medication
1) Vitamin A
A patient with HTN and T2DM presents with L-sided weakness and facial droop. What imaging modality should you start with?
noncontrast head CT
What medications should be avoided in individuals with Parkinson’s?
Avoid antipsychotics as they are dopamine antagonists
Are EEGs for new onset seizures helpful without seizure during assessment?
yes
A patient has acutely elevated ICP. Can you give them D5W?
NO! Hypotonic fluids will only worsen the ICP
Noncontrast CT shows a right-sided crescent shaped hyperdensity. What is the diagnosis?
subdural hematoma
A 15 yo gymnast presents with lower back pain without radiculopathy. Imaging reveals bilateral pars intraarticular defect, with normal L5-S1 alignment. What is the diagnosis?
Spondylolysis
A 30 yp cashier presents with 3 months of progressive neck pain, weakness, increased reflexes, and parasthesias of hands. What is the diagnosis?
cervical myelopathy
(UMN, bilateral, progressive)
Caused by compression of the spinal cord in the cervical region
A patient presents with a non-specific pituitary tumor. In gerneral, what treatment should you avoid? What are better options?
AVOID = temporal excision
GOOD = transphenoidal excision, transcranial, radiotherapy, antisecretory agents
A 52 yo patient presents with tinnitus, vertigo, and hearing loss. What is the diagnosis?
Vestibular schwannoma
A 32 yo man presents following a motor vehicle crash with loss of sensation from the chest down and inability to move bilateral legs. What is the next best step?
IV fluids and/or O2 therapy and/or catheter
Patient presumably has spinal shock. Spinal shock can lower blood pressure and hypoventilation which can increase the extent of neurological impairment. In addition, bladder overdistention can result from spinal shock