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1
Q

67 yr old woman makes aptment to see PCP. For 6 months, she has experienced fatigue, worry regarding health, waking up at 3:30 am every morning. a ten pound weight loss, difficulty concnetrating and a sense of depression and not being interested in her usual activities. The most significant change in the patients life is that her husband of 40 yrs retired approximately a year earlier, what is the diagnosis

A

Major depressive disorder - primary symptoms are mood symptoms and she meets criteria. Her symptoms exceed those for adjustment disroder and therefore a more serious illness is diagnosed. Additionally symptoms have not been present for 2 years henche she does not meet criteria for dysthymia

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2
Q

Why does exercise decrease major depressive disorder symptoms

A

It increases neurogenesis (running in particular)

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3
Q

75 yr old feels sadness inadequacy and helplessness. Her medical histroy is signifcant for bout of major depressive disorder when she was in her late forties.
At that time she was successfully treated with a drug that managed her depression (X) but she recalls during treatment she felt light headed and occassionally felt faint when rising from a chair. given her age she is concerned. To avoid hypotension, physician prescribes a different drug (Y). What are X and Y possibly?

A

X: MAOI
Y. SSRI

postural hypotension is side effect of TCA, MAOI, and trazadone (5HT2 antagonist).
Drug Y should be either an SSRI or SNRI to avoid this side effect.

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4
Q

Girl asks Dan of their plans how theyre going to spend the day. When he dismisses her, alex experiences an abrupt mood swing and confronts DAn about his callousness. Dan then berates her and decides to leave. Alex’s anger is turned inward and she cuts her wrists

mood lability and suicidal gesture are what two defense mechanisms

A

Splitting and passive aggression.

Splitting is black and white thinking which can lead to all or nothing feelings and behavior such as that which is labeled mood lability.
Passive aggression is an ego defense that turns an aggressive impulse inward and is hypothesized to underlie the suicidal gestures charactersitic of BPD.

Dissociation while a defining element of BPD (and histrionic) is defined as a drastic shift to a MORE PLEASANT affect. Expression of dissociation leads others to believe shallow and dramatic.

“Acting out” is acting on an observable impulse so to avoid being consciously aware of it. Assaults in Antisocial personality.

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5
Q

A young child starts looking under a blanket where he last found the toy rather than the place where the examiner placed it. What age and piaget level is the child showing

A

Sensori motor age 12 months - object permanence.

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6
Q

What quality infers the greatest risk of suicide

A

Expressing hopelessness.

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7
Q

Which learning theory suggests that thoughts play a very important role in the development of new behavior

A

Social learning theory - posits learning and behavior change is not simply based on a stimulus-response association but that thoughts play a major role in behaviors that are learned and performed. This forms foundation of CBT.

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8
Q

What type of operational learning is this

Prescribed Zoloft for depression

A

-negative reinforcement - reducing and or eliminating depression. DESIRABLE

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9
Q

Patient A: limps into office, requesting pain management for previously diagnosed osteoarthritis
Patient B: has a history of CAD asks for tums for heartburn
Patient C: seeing a counselor for mild depression, would like to take disability leave.
Patient D: acute unilateral stocking-glove numness in left arm
Patient E: convinced he has fatal illness would like you to figure out what it is. He checks body for skin lesions multiple times a day.
Which is NORMAL ILLNESS BEHAVIOR

A

Patient A: limping
Somatization is someone’s behavior in response to physical symptoms , these are usually adaptive signs of disease and facilitate patients seekign appropriate medical attention.

Patient B: denial of illness may be maladaptive
Patient C: distress or disability induced symptoms is disproportionate with known pathology.
Patient D: or inconsistent with known pathology
Patient E: illness anxiety disorder - chronic and excessive anxiety about one’s health with excessive health related behaviors but with minimal or no associated symptoms

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10
Q

Negative symptoms of schizo

5A’s, Plant

A
aPathy 
aLogia (poverty of speech, thought) 
Affective flattening 
aNhedonia (withdrawal)
aTtention deficit
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11
Q

All substances in intoxication can cause psychosis except for 3?

2 substances that cause psychosis in withdrawal phase

A

Caffeine (induces two disorders: anxiety and insomnia)

Nicotine (zero syndromes resulting from intoxication and withdrawal - some anxiety is different from full disorder)

Opioids - (intoxication doesn’t lead to psychosis)
____________________________

Alcohol - delerium tremors - delerium is psychotic symptom

Sedatives do the same

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12
Q

EPS (standard of typical antipsychotics)

A

Parkinson - like syndrome with bradykinesia, rigidity, and tremor

Akathisia

Dystonias

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13
Q

Que son los CAGA preguntas?

A

C: ever felt like you should CUT down on drinking

A: have people ANNOYED you by criticizing drinking

G: have you ever felt GUILTY for drinking

E: have you ever had a drink in the morning to steady your nerves or to get rid of hangover.

Two positive responses are considered a positive test, one is suspicious so ddo an assessment

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14
Q

Clarisa is an 8 year old who was admitted to the pediatric hospital with severe abdominal pain of 3 days duration. The workup has been entirely negative beyound moderate constipation that responded to a course of laxatives. Her nurse suggested that the child is anxious and suggested that she be evaluated. You learn from mom that Clarisa has always worried and is irritable for things in the past 9 months about things and sometimes worries about unfamiliar situations. For the past 2 weeks she has been reluctant to attend school and fearful of taking part in a school play. She did have problems with separation from her mom in preschool but non since then. Which one of the following additional pieces of information about Clarisa.

A

Fear of dark and a history of separation anxiety would point to separation anxiety disorder but the 4 week duration of school avoidance and other symptoms to meet the criteria are not present. Children with anxiety disorders are often eager to please and often have the temperament or risk factor of being shy or have behavioral inhibition that predisposes them to differing anxiety disorders that alternate over time. No specific social situation seems to be the precipitating event suggesting that social phobia is not a likely diagnosis even with her long standing social inhibition.

Generalized anxiety disorder with the duration criteria and with the chronic worry, criteria are met.

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15
Q

What is one of the most commonly associated feature of ASD?

A

Hyperaccusis - over sensitive hearing

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16
Q

Sal is a 14 year old boy seen in the pediatric clinic. His mother expresses concern that Sal has done poorly in school since second grade because of an inability to sit still and his being easily distracted and highly impulsive. Over the past few months, he has become defiant when asked to do his homework and certain household chores. Mom reports that Sal has a long standing problem with mood changes, being unpredictable, having high energy and not sleeping as much as his younger and older siblings. He has been diagnosed with ADHD in second grade after darting in front of a car but responded poorly to a trial of methylphenidate. During your interview he spoke rapidly, appeared tired, reported feeling good, but some days being irritable a lot of the time over the past few months. He made good eye contact, reported often getting spacey in school and home and showed no other symptoms of ADHD. What is the most likely diagnosis

A

Attention-deficit/hyperactivity disorder, combined

Symptoms were present since second grade, thus age criteria is met and problems persisted over time. He has had ADHD diagnosis and symptoms of course would need to be confirmed
*he did not show ADHD signs in clinic is not reason to eliminate the ADHD diagnosis.

Major depression is a possbility with occasional irritability and problems with concentration, sleep, fatigue and high activity. These symptoms are insufficient persistence, number or severity for depressive diagnosis

Bipolar can be considred in the differential as suggested by his irritability and rapid speech but the dangerous behavior descrbied sounds more impulsvie than planned and there is no reported history of depression or manic or hypomanic behavior nor a week long episode of increased goal directed activity. The oppositional and defiant behavior is causing distress and dysfunction but does not meet duration criteria and seems more related to frustration with school work. The year long persistence of severe disruptive behavior occurring several times a week over a year long period and present before 10 years is not present for serious consideration of disruptive mood dysregulation disorder.

17
Q

25 year old woman is accompanied by her schools counselor to a psychiatric evaluation. There has been a decline in her school performance due to intrusive thoughts that people from Homeland security are following her around campus. There is no evidence of auditory hallcuinatiosn problems formulating thoughts, depression or mania. When asked if she truly believes she is being followed, she reports that she is aware the thoughts are a product of her own mind

A

Obesessive compulsive disorder:

-Patient present with abnormal thoughts that are clinically impairing as evidenced by a decline in her school performance .chief in the differential are psychotic disorders as opposed to anxiety disorders (if the abnormal thoughts are not delusions. The abnormal thoughts are not fixed as evidenced by the patients report she’s aware that they are a product of her own mind. Since signs of depression are not pronounced, MDD and GAD are unlikely. Despite no evidence of compulsive behaviors (not required for diangosis) OCD is most likely

18
Q

Memory loss in relation to the dopaminergic pathways is related to which one

A

Mesocortical pathway - decreased activity

19
Q

A patient presents with auditory hallucinations and initially appears to be afflicted with schizophrenia Upon taking more hisotry it is revealed that while initially diagnosed with schizophrenia 2 decades ago, he’s also experiencing co-occurring depressive symptoms for the past 12 weeks. What is the most likely diagnosis

A

Schizophrenia and Major Depressive Disorder

co-occuring mood symptoms rules out schizophrenia. Since the co-occurring mood symptoms have not been present for the duration of the episode (2 decades ago), schizoaffective disorder is unlikely. The history is not indicative of a primary mood diosrder that has progressed to a severe state.

20
Q

A young male is brought to ER suffering an overdose of cocaine after IV, his signs and symptoms are likely to include

A

tachycardia, with the possibility of an arrhythmia, infarct or stroke (blocks reuptake of norepinephrine at sympathetics which results in greater risk of cardiotoxicity.

Mydriasis, hypertension, hyperthermia

21
Q

Nystagmus is a common sign for overdose of what

A

*nystagmus is common for overdose of PCP!

22
Q

What are common adverse effects of methylphenidate

A

insomnia, loss of appetite, mydriasis,

23
Q

54 year old female is seen in emergency room after running a red light and hitting another car. She is angry and upset. Her urine test is negative for alcohol. Her physical examination also shows distended epigastric veins across the umbilicus and icteric sclera. What is the issue

A

Alcohol use disorder

24
Q

25 year old presents with having the flu. He reports fever, nausea, runny nose and hurting all over. Upon physical exam you observe multiple puncture wounds over several superficial veins of the forearm. The most likely cause is

A

Opiod withdrawal - identified as flu like syndorome including GI effects, fever, rhinorrhea, lacrimation and arthralgias.

Cocaine withdrawal is similar to a major depressive episiode. PCP intoxication is characterized by behavioral or psychological disturbances of impulsiveness, agitation and belligerence along with physiologic signs

25
Q

A 10 year old boy was brought into his pediatrician by his mother. The mother reports that the patient has been getting into fights with his eight year old sister. THis has been going on for the past six months, She states that he often seems angry and deliberately annoys his sister. According to the mother he does not act this way with friends

A

normal development

-fighting is confined to a sibling

26
Q

What are environmental risk factors for conduct disorder

A

Exposure to violence
Low levels of parental monitoring
Inconsistent discipline

Not divorced parents

27
Q

46 yr old concerned about memory loss over the past few months. She finds it hard to remember thigns said to her by coworkers and is frequently misplacing thigns. SHe had a mother with alzheimers starting in her 70s and is concerned she is developing it. SHe works as a banking executive and has been under a lot of stress at work. Her sleep, appetite, motivation have been poor. She denies depression but admits things just aren’t fun anymore. Her MSE is significant for delayed recall of 1 of 5 items but can recall all give with cues. What is the most likely cause of memory loss

A

While dementia can certainy occur in a patient in their 40s, it is far less common than it would be later in life. The msot common causes of dementia in this age group are alzheimers disease and FTD but her complaints are non specific and do not point clearly to either. The fact that her mother had AD is important but does not predict an increased likelihood for early onset dementia. In contrast she does meet criteria for major depressive disorder and the type of memory difficulty she has is consistent with this condition. Depression and sleep disorders are common in this age group and important sources of memory and attention difficulties. Being able to identify depression in thsi case and provide reassurance is improtant.

28
Q

What is the critical difference between dementia and mild cognitive impairment

A

Dementia requires significant functional deficits

-MCI refers to cognitive deficits being worse than expected for normal aging were present but not enough to qualify for dementia.
MCI has two major distinguishing features from dementia -
1. cognitive decline occurs in a single cognitive domain (just memory or just executive function - dementai must affect two or more
2. does not have severe functional deficits

29
Q

He eats a large pizza by himself four to five times a week. 20 yr old with 20 lbs of weight gainin one year acknowledges eating too much food. Medical workup does not indicate any current medications or pathologies

A

Eating disorder

30
Q

16 yr old complains of strange nighttime experiences. He has had a sense that someone is in the room with him as he is falling asleep and sometimes feels like he can’t move when he wakes up in the morning. He has passed out at exciting basketball game and was evaluated in the ER with no positive findings. What would be the next appropriate test

A

Presenting narcolepsy
-hypnagogic hallucinations, sleep paralysis and cataplexy (the fourth in the tetrad is day time sleepiness)

Narcolepsy is diagnosed with a multiple sleep latency test performed at a sleep center. An EEG will not be useful. Orexin is not detectable in plasma, although production reduction in the hypothalamus is indicated

31
Q

a 24 year old woman presents to ER after being raped. She can tell you where she is and the date but can not recall her name. The patient is aware that she doesn’t remember he name. This is

A

Dissociative amnesia - depersonalization is where patient would not recongize parts of her own anaotmy. With DID, the patient would not be aware of her amnestic response.
Gansers syndrome is a syndrome with almost correct answers

32
Q

Patinet has mild decrease in left lateral gaze during smooth pursuit., had difficulty walking and was stumbling. He was aware he was at the hospital but couldn’t name which one and could only name the year correctly. serum revealed alcohol is present. What is next step?

A

Give IV thiamine - Wernicke’s encephalopathy is present

Although this only presents in 16-20% of patients. Thiamine administration has no downside since it is water soluble, it just gets peed out.

If this was withdrawal give benzos

33
Q

70 yr old brought to clinic by her daughter due to concerns of sleeplessness, isolation, weight loss, falls and anxiety over the past year. In addition the patient has been staying at her daughters home the past 3 days, she began shaking, hallucinating, perspiring prfusely and wanting to return to her own home. The patient has no history of medical problems. What is goign on?

A

Alcohol withdrawal - which causes symptoms of anxiety, tremor, flushing and onset within 48 hours of last drink. Associated symptoms include rapid pulse, increased blood pressure and temperature as well as hallucinations and confusion when more severe. Neither marijuana nor alcohol intoxication is associated with increases in pulse, blood pressure or temperature. Cocaine withdrawal does not include changes in vital signs and is usually mild. Opiod withdrawal is characterized by nausea, vomiting, cramps and myalgias and not confusion

34
Q

Which disorders are impulse control NEC (not elsewhere classified

A

Intermittent explosive, kleptomania, pyromania