Test 5 Study Guide Flashcards
HIV replicates what?
HIV becomes a parasite for helper T cells and it alters them. (Reverse transcription)
HIV transmission?
Blood, semen, vaginal secretions, and breast milk
Subtypes of HIV
HIV 1: composed of 4 groups M,N,O,P (M mutates easily)
A-k have multiple strains
HIV 2: primary infection in Western Africa
Hiv 1: Group M Subtype B is more prevalent
What behaviors increase the risk of HIV?
*unprotected sex
*contact with body fluids
*sharing needles and syringes
*body piercings, tattoos, dental work
*breastfeeding
Signs and symptoms of HIV?
Flu like symptoms, fever, swollen lymph nodes, Weightloss, enlargement of liver and spleen, headache, nausea and vomiting
In women gynological problems that occur with HIV?
Abnormal pap
Genitalia warts
Pelvic inflammatory disease
Vaginitis
How expensive are HIV meds?
500,000 or more
Standard guidelines for starting HIV meds
Initiate antiretroviral drug therapy
What is the goal for antiretroviral therapy? Why would the pt become resistant to meds?
Goal is to bring viral load to undetectable
Resistance happens because of mutations
What do NRTIS do? NNRTIS?
NRTIS: interfere with the ability to make a genetic blueprint of the virus.
NNRTIS: bind directly to the reverse transcriptase and prevents transcription
What do protase inhibitors do? Fusion Inhibitors?
Pi’s interfere with the maturation of the viral copies manage to escape from the host T4 cells. They most likely control the virus.
FI’s blocks the CXCR4 receptor, reserved for people who are resistant to
Common opportunist infections associated with AIDS.
Pneumocystis pneumonia
Candidiasis
Cytomegalies infection
Cryptospordiosis
What is Aids Dementia complex? What are the symptoms?
A neurological condition that causes degeneration of the brain, effectively mood, cognition, and motor functions.
Patients exhibit forgetfulness, limited attention span, decreased ability to concentrate, delusional thinking, mood range from irritability to euphoria.
What is distal sensory polyneuropathy?
Abnormal sensation, such as burning and numbness in feet and later in the hands. DSP responds well to drug therapy.
What is OSHA recommended when catering for patients with AIDS?
*transport specimens of body fluids in leak proof containers
* clean, disinfect, or discard utility gloves for cleaning
*remove barrier garments asap after leaving client’s room.