test 3 Flashcards
Positive intropic drugs do what to the heart?
can increase oxygen demand of the heart muscle
can damage contractile apparatus
can increase tendency for arrhythmia
positive intropic drugs…
cardiac glycosides
catecholamines
bipyridine derivaties
mixed dilators
cardiac glycosides indications
impaired cardiac contraction CHF
atrial arrhythmia
cardiac glycosides dosage forms
digoxin elixir
cardiac glycosides adverse side effects
anorexia, vomitting, diarrhea
arrhythmia
monitor pet for GI signs
catecholamines are
sympathomimetics
catecholamines do what?
increase force and create of muscle contraction
constrict peripheral blood vessels elevate blood glucose levels
can be used for cardiac resuscitation
catecholamine drugs
epinephrine
dopamine
dobutamine
catecholamine adverse side effects
hypertension, anxiety and excitability
Isoproterenol is only used for
atropine-resistant bradycardia
Dopamine uses…
heart failure associated with anesthetic emergencies
after cardiac resuscitation
oliguric renal failure
dopamine adverse side effects
vomitting, tachycardia, dyspnea
Dobutamine does what
increase cardiac output
doesn’t cause arrhythmia’s
doesn’t increase heart rate
administered IV infusion in emergency cases
Bipyridine derivates drugs…(2)
amrinone-IV
milrimone- oral
bipyridine derivatives work by…
inhibiting enzymes that lead to increase In cellular calcium
anti arrhythmic drugs
xylazine
halothane
digoxin
thiobarbiturates
Class IA drugs (2)
quinidine
procainamide
quinidine is used for
long term use
oral
ventricular contractions
ventricular tachycardia
quinidine side effects
anorexia, vomiting, weakness
laminitis in horses
Procanamide uses
premature ventricular contractions
ventricular tachycardia cardia
atrial tachycardia
prcanamide side effects
GI, hypotension
all dose related
Class BI drugs (3)
lidocaine
tocainide
mexiletine
Lidocaine uses
uses for emergencies
side effects of lidocaine
rare- drowsiness, depression, ataxia
Tocainide and mexiletine given how?
may be given orally
Class IC drugs
seldom used
Flecainide and encainide
Beta adrenergic blockers (2)
propanolol
Atenolol
Propanolol uses
hypertrophic cardiomyopathy
various arrhythmias
in cats to treat systemic hypertension and hyperthyroidism
propranolol side effects
bradycardia
hypotension
lathargy
propranolol must be tapered off therapy because…
they may develop tachycardia or hypertension if stopped abruptly
Atenolol uses
supraventricluar tachyarrythmias
hypertension
cardiomyopathy
Atenolol adverse side effects
bradycardia lethargy syncope
heart failure
calcium channel blockers do what
depresses contractile mechanisms
depresses automaticly and impulse transmission
Verapamil HCl uses
tachycardia
atrial flutter