Test 2- Schizophrenia, Psychosis, Cognition Flashcards
What are DSM criteria for Dx of schizophrenia?
2 or more symptoms for at least 1 month and at least one specific symptom (1,2 or 3)
What are the 3 specific symptoms for DSM Dx of schizophrenia?
- Impairment of a major area of functioning (self care, interpersonal relations, or work)
- Signs lasting for at least 6 months
- Schizoaffective + bipolar or depression; + psychotic features
What are the s/s of schizophrenia? Which are positive? Which are negative? name at least 2 of each
Positive: hallucinations, delusions, disorganized speech, bizarre behavior
Negative: blunted affect, poverty of thought (alogia), loss of motivation (avolition), inability to experience pleasure or joy (anhedonia)
What is a prodromal symptom? What are some related to schizophrenia? Name at least 3
An early s/s before dx of disorder
Social withdrawal, hyper religiosity, odd or schizotypal preoccupations, worsening hygiene/self care, deteriorating academics, deep sense of wrongness (dysphoria), bizarre behaviors, other conduct problems, substance abuse, aggressive behaviors
What are DSM criteria to Dx schizoaffective disorder?
Uninterrupted duration of illness during which there is a major mood episode (manic or depressive) in addition to the criteria for schizophrenia
What are s/s of schizoaffective disorder?
Delusions, racing thoughts, anxiety, hopelessness, hallucinations, psychosis, impulsivity, restlessness, rapid speech
What is catatonia?
Behavioral syndrome causing patients to be unable to move normally
What are some s/s of catatonia? Name at least 3
Sustained abnormal positions, stupor/unresponsiveness, waxy flexibility, weakness, staring, rigidity, echolalia, purposeless/repetitive overactivity, mutism, echopraxia, limited range of emotions, deep sadness
What does EPS stand for/mean? What causes it?
EPS= Extrapyramidal Symptoms. It is alterations in movement (akathisia, tardive dyskinesia, acute dystonia, pseudoparkinsonism) caused by a blockade of dopamine or a depletion in the basal ganglia
What does acute dystonia look like? How is it treated?
Muscle cramps in the head/neck/abdomen/pelvis; can lead to abnormal posture/paralysis. Treat immediately with cogentin and can be treated with Benadryl
What does pseudoparkinsonism look like? How is it treated?
Stiffened extremities/fine motor tremors; antipsychotic + anticholinergic or mantadine
What does akathisia look like? How is it treated?
Internal and external restlessness, can include rocking/pacing/grunting or moaning; treat with a beta blocker, benzos, and/or anticolinergic
What does tardive dyskinesia look like? How is it treated?
Facial grimaces, tongue movements, lip smacking, or tremors. There is currently no treatment-it is permanent
How is Lithium used with schizophrenia?
Atypical- it is normally used as a mood stabilizer-it reduces aggressive behaviors
How are SSRIs, SNRIs or MAOIs used with Schizophrenia?
Atypical- they are normally used as antidepressants. They treat depression r/t schizophrenia
How are anti-tremor meds used with schizophrenia?
It is used to treat abnormal muscle movements and can treat some EPS in schizophrenia patients. Benztropine
How do BP meds help with Schizophrenia?
Clonidine is an antihypertensive and it can act as a sedative
Propanalol is a beta blocker and it can be used for tremors
Is Fluphenazine (Prolixin) a typical or atypical antipsychotic?
Typical
is Haloperidol (Haldol) typical or atypical?
Typical
Is Chlorpromazine (thorazine) typical or atypical?
Typical
Is Loxaine (Loxitane) typical or atypical?
Typical
How do typical antipsychotics work? Side effects?
They are dopamine antagonists
They may cause EPS, neuroleptic malignant syndrome, tachycardia, agranulocytosis, seizures, arrhythmias, and hypotension
Is clozapine (clozaril) typical or atypical? Side effects?
Atypical; severe neutropenia leading to infection, agranulocytosis, and possibly death
Is aripiprazole (abilify) typical or atypical? Side effects?
Atypical; interact negatively with SSRIs/antidepressants, can cause sedation or drowsiness