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NUS 210 Meds > Test 2 Meds - Cancer & HIV > Flashcards

Test 2 Meds - Cancer & HIV Flashcards

1
Q

Antineoplastic
agents 2 examples

A

Doxorubicin and Vincristine

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2
Q

Doxorubicin type of drug

A

Anti-tumor
antibiotic

Anthracyclines

Cell cycle non-specific

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3
Q

Doxorubicin acute side effect

A

Bone Marrow Suppression

Nausea and vomiting

Stomatitis,

Red urine and tears

Alopecia,

Cardio-toxicity,

CHF

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4
Q

Doxorubicin delayed or chronic side effects

A

Cardiomyopathy, CHF

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5
Q

Doxorubicin Nursing Considerations

A

Administer antiemetics prior to
treatment.

Monitor EKG and echo

Monitor for extravasation- central line preferable

Monitor for chest pain and

SOB

Monitor WBC, ANC (neutrophil count), platelets, Hbg &Hct, liver enzymes

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6
Q

Doxorubicin Patient Teaching

A

Good oral hygiene,

No alcohol in mouthwash

Notify Provider for SOB or CP

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7
Q

Vincristin type of drug

A

Vinca alkaloid
Cell cycle specific

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8
Q

Vincristine side effect

A

Weakness, paresthesia,
sensory loss &
decreased reflexes

alopecia

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9
Q

Vincristine Nursing Considerations

A

Monitor for extravasation-
central line preferable

Monitor WBC, ANC, platelets,
Hbg &Hct
Liver enzymes

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10
Q

Vincristine Patient Teaching

A

Advise to report side effects
Good mouthcare

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11
Q

Biological and Targeted Therapies Examples

A

Trastuzumab
Imatinib
Filgrastim
Erythropoietin

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12
Q

Rastuzumab used in

A

Targets those breast cancer cells that have an over expression of the HER
protein

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13
Q

Rastuzumab type of therapy and how is it given

A

MOAB
IV

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14
Q

Rastuzumab Side Effects

A

Nausea and vomit

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15
Q

Rastuzumab Nursing Considerations

A

Monitor:
Hypersensitivity reaction,
Cardio toxicity,
Tachycardia,
CHF,
Dyspnea and edema,
Monitor fluid status

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16
Q

Rastuzumab Patient Teaching

A

Report SOB and chest pain

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17
Q

Imatinib used in…

A

Chronic myeloid leukemia (CML)

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18
Q

Imatinib type of drug and how is it given

A

Tyrosine Kinase inhibitor
po

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19
Q

Imatinib Side effects

A

GI discomfort,
Nausea and vomit
Flu like symptoms

20
Q

Imatinib Nursing considerations

A

Take with food,
give anti medic
Tylenol for mild symptoms
Monitor K levels, for edema,
CBC for neutropenia

21
Q

Imatinib Patient Teaching

A

Hygiene to prevent infection

22
Q

Filgrastim what does it do how is it given?

A

Decrease risk of infection
Increase neutrophil
SQ

23
Q

Filgrastim side effects

A

Bone pain

24
Q

Filgrastim Nursing considerations

A

Monitor CBC
Tylenol for pain

25
Q

Erythropoietin what does it do how is it given?

A

Increase the
production of RBC’s
SQ

26
Q

Erythropoietin Side effects

A

Increased BP body aches

27
Q

Erythropoietin Nursing Considerations

A

Monitor HBG, head aches,

28
Q

Hormonal Therapy Examples

A

Leuprolide
Tamoxifen

29
Q

Leuprolide
why is it used?

A

Used instead of surgical
castration

Stops the testes from
producing testosterone

30
Q

Leuprolide how is it given?

A

Given Sq or IM

31
Q

Leuprolide Drug class

A

Gonadotropin releasing hormone agonist
Stops the testes from
producing testosterone

32
Q

Leuprolide side effects

A

Hot flashes, decreased libido,
& gynecomastia
Monitor for dysrhythmia and
assess pulmonary edema

33
Q

Leuprolide Nursing consideration

A

Increase Ca ++ and vit D in diet,
exercises to increase bone density
Monitor PSA

34
Q

Tamoxifen Drug class

A

Selective estrogen receptive
modulator

Estrogen receptor blocker

35
Q

Tamoxifen how does it work

A

Attaches to hormone
receptors in breast cancer
cells

(The cancer can’t access the
hormone it needs to grow)

36
Q

Tamoxifen how is it given

A

orally

37
Q

Tamoxifen Side effects

A

Nausea and vomit
Pulmonary Embolism, hot flashes

38
Q

Tamoxifen Nursing Considerations

A

Monitor for abnormal bleeding
Monitor Ca+2 levels,
Cataracts, retinopathy

39
Q

Cytoprotectants

A

Amifostine and mesna

40
Q

Apetite stimulant

A

Megestrol

41
Q

Suppress production of Stephen and testosterone

A

Goserelin

42
Q

Estrogen receptor down regulators

A

Induce degradation of estrogen receptors

43
Q

Estrogen antagonist

A

Tamoxifen
Anastrozole
Trastuzumab

44
Q

Biological response modifiers

A

Interleukin
Interferon

45
Q

Types of immune therapy

A

Biological response modifiers
Monoclonal antibody
Targeted therapy
Cancer vaccines

46
Q

The only fda approved cancer vaccine

A

Sipuleucel-T
For prostate cancer

47
Q

Phototherapy is used in what type of cancer

A

Esophageal
ocular tumors.
Upperairway tumors
No melanoma skin cancer

NUS 210 Meds (1 decks)

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