Test 2 BT's Version B

Question 1

1. Induction of ventromedial portion of the somite to become sclerotome is caused by:

Answer 1

SHH (Sonic Hedgehog)

Question 2

2. Listed below cells are neural crest derivatives, except:

Answer 2

Osteocytes

Question 3

3. Dermatomyotom region of the somite is marked by

Answer 3

PAX3

Question 4

4. Holt-oram syndrome is caused by mutation in the gene:

Answer 4

TBX5

Question 5

5. Trisomy 18 causes:

Answer 5

Edwards syndrome

Question 6

6. In the human embryonic development occurs:

Answer 6

Blastocyte

Question 7

7. If the neural tube fails to close in the cranial region, the defect is called:

Answer 7

Anencephaly

Question 8

8. Urogenital structures develop from:

Answer 8

Intermediate mesoderm

Question 9

9. Respiratory distress syndrome develops as a result of:

Answer 9

Deficiency of surfactant

Question 10

10. Indicate the homeobox-containing transcription factor responsible for establishing left-sideness of the embryo:

Answer 10

PITX2

Question 11

11. In the scheme of primary ovary follicle with the arrow is indicated:

Answer 11

Theca interna

Question 12

12. Epithelial lining of the primitive gut develops from:

Answer 12

Endoderm

Question 13

13. Indicate the inhibitor of BMP in the process of neural induction:

Answer 13

Chordin

Question 14

14. In the process of pancreas development, SHH expression in the gut endoderm destined to form the dorsal pancreatic bud is repressed by:

Answer 14

FGF2

Question 15

15. Indicate the transcription factor promoting crest cell migration from the neuroectoderm:

Answer 15

SLUG

Question 16

16. In the kidney development, the process of branching and growth of the uretic buds is stimulated by:

Answer 16

HGF

Question 17

17. Indicate gene important for designating the forebrain and midbrain:

Answer 17

Version B: LIM1

Version A: OTX2

Question 18

18. … Disease being an example of trinucleotide repeat disorders:

Answer 18

Fragile x syndrome

Question 19

19. Indicate a primary brain vesicle:

Answer 19

Mesencephalon

Question 20

20. Development of the cerebellum is regulated by:

Answer 20

EN2

Question 21

21. Apert syndrome is caused by mutation in the gene:

Answer 21

FGFR2

Question 22

22. Indicate receptors for WNT proteins (WNT signaling pathway);

Answer 22

Frizzled family of proteins

Question 23

23. In the process of spermatogenesis, in the result of meiosis 1 are formed:

Answer 23

Primary spermatocyte

Question 24

24. In the kidney development, conversion of the mesenchyme to an epithelium for nephron formation is regulated by:

Answer 24

Nodal

Question 25

25. Indicate the transcription factor specifying the esophagus and stomach (inducing development of esophagus and stomach):

Answer 25

SOX2

Question 26

26. Human morula consist of:

Answer 26

16 cells

Question 27

27. Polysperm is prevented by:

Answer 27

Cortical reactions

Question 28

28. Indicate disease developing when neural crest cells fail to migrate:

Answer 28

Congenital megacolon

Question 29

29. A condition in which transposition of the viscera in the thorax and abdomen occurs, called:

Answer 29

Situs inversus

Question 30

30. In the diagram are shown changes in a hormone concentration in peripheral blood during the menstrual cycle. This hormone is:

Answer 30

FSH