Test 2 - Breast Images

Question 1

Normal epithelial cells
Small cohesive groups
Monolayer sheets
Occasional complete terminal duct-lobular units
Nuclei are oval with regular outlines, 8-10µm diameter
Inconspicuous nucleoli
Evenly dispersed chromatin pattern
Scanty delicate cytoplasm

Answer 1

Benign

Question 2

Cellular
Epithelial fragments occur as large/flat/monolayered sheets
Some ‘fingerlike’ projections (similar to that seen in FA)
There is a bimodal pattern of single bare/bipolar nuclei in background
Adipose tissue may be present
Moderate nuclear variation and atypia may be seen
Seen only in males

Answer 2

Gynaecomastia

Question 3

Cohesive sheets of benign ductal cells arranged in flat honeycomb sheets, no loss of polarity with distinct cell borders
May have cystic bg, may be clean
Bare myoepithelial nuclei present
Apocrine cells
Cystic/foamy macrophages (not as many as benign cyst)
Fat and stroma

Answer 3

Fibrocystic Change

Question 4

Answer 4

Low Grade Duct Carcinoma

Question 5

Answer 5

Lactating Breast

Question 6

Answer 6

Mastitis

Question 7

Answer 7

Fat Necrosis

Question 8

Answer 8

Fibroadenoma

Question 9

Answer 9

Epithelial Hyperplasia
ADH
Low grade DCIS

Question 10

Answer 10

Intraductal Papilloma

Question 11

Answer 11

Phyllodes Tumour

Question 12

Answer 12

Lobular Carcinoma

Question 13

Answer 13

Mucinous Carcinoma

Question 14

Answer 14

Infiltrating Duct Carcinoam

Question 15

Answer 15

Invasive Ductal Carcinoma

Question 16

Answer 16

Low Grade DCIS

Question 17

Answer 17

Low Grade DCIS
High Grade DCIS

Question 18

Answer 18

Tubular Carcinoma

Question 19

Answer 19

Medullary Carcinoma

Question 20

Answer 20

Infiltrating Lobular

Question 21

Answer 21

Papillary Carcinoma

Question 22

Answer 22

Pagets