Test 2 Flashcards
In DNA what matches up with A and C
A>T
C>G
In RNA what matches up with A and C
A>U
C>G
Codon
Group of 3 nucleotides
Codes for AUG, MET
Codes for methionine (start code)
Anti codon
Opposite of codon
Meiosis
Production of sperm cells
Somatic cell
All cells in body accept sperm cells
Gamete
Sperm cells ( sex cells)
Diploid
2 sets of chromosomes
Haploid
Having 1 set of chromosomes
Interphase
Where cell spends most of its time
Mitosis
Growth and repair
Sister chromatids
A set of chromosomes before division
Homologous chromosomes
A set of chromosomes during division
Prophase
- Nuclear envelope breaks down
* Spindle fibers emerge from the centrosomes
Prometaphase
Mitotic spindle microtubules attach to kinetochores
Metaphase
Lined up in the middle
Anaphase
Centromeres split in two
Telophase
- Starts to separate
* nuclear envelope starts to surround the new sets of chromosomes
Cytokinesis
Formation of two new cells
Stem cells form what ?
Cord blood
Totipotent
First embryonic cells formed
Pluripotent
Second cells to form
Precursors
Unipotent
Cells that can only divide and make more of that same type of cell
Epidermis
- Outer most layer of skin
* dead skin cells
Stratum basale layer of skin
Deepest
•includes merkel cells (sensory)
•includes melanocytes (pigment)
Stratum spinosum
Keratin synthesis begins Langerhans cells ( engulfs bacteria and foreign particles)
Stratum granulosum
Cells become flattened and thicker
Keratohyalin
Equals glue
Stratum lucidum
Very thin layer in thick skin Includes eleiden ( water proof barrier)
Stratum corneum
Outer most layer of skin,
Cells are dead and packed in and provides protection
How often are skin cells replaced?
Every four weeks
Dermis
Middle layer of skin
Sebaceous gland
(Oil) keeps hair hydrated
Dermis
Middle layer of skin
Papillary layer
Most superficial layer of the epidermis
Adipocytes
Insulates
Elastin fiber
Allows movement
Collagen fiber
Provides strength
Hypodermis
The layer that connects bones and muscle to skin
Papillary layer
Most superficial layer of the epidermis
Phagocytes
Defense cells that’s helps fight off bacteria and infection
Albinism
Inability to produce melanin
Vitiligo
When melanocytes lose their ability to produce melanin
Hair
Includes hair shaft, medulla, cortex, cuticle
Nails
Nail root and hyponychium
Eccrine sweat glands
Doesn’t smell
Produces sweat all the time
Apocrine sweat gland
Smells strong and doesn’t produce all the time
Integumentary functions
Protection
Sensory function
Thermoregulation
Vitamin D synthesis
Acne
When hair follicles get blocked by sebum
Burns (degree)
First-superficial to epidermis
Second-epidermis and part of dermis
Third-extends thru epidermis and dermis
Fourth-affects bone and muscle
Skeletal system functions
Support Movement Protection Mineral and energy storage Hematopolesis (production of blood cells)
Types of bones
Long Short Flat Irregular Sesamoid
(Bone type)
Long
Two distinct ends with a shaft
Ex. Femur and phalanges
(Bone type)
Short
Cube like
Ex. Carpals and tarsals
(Bone type)
Flat
Two parallel sides
Ex. Sternum and skull
(Bone type)
Irregular
Irregular shape
Ex. Vertebra and sphenoid
(Bone type)
Sesamoid
Sesame seed like
Ex. Patella
Diaphysis
Shaft in the middle of the bone
Epiphysis
Distinct ends of the bone
Endosteum
Inner layer of bone
Periosteum
Outer layer of bone
Compact bone
Heavy
Spongy bone
Light
Osteoblast
Building up bone
Osteogenic cell
Undifferentiated stem cells that can turn into other cells
Osteoclast
Breaking down bone
Osteocyte
Mature bone cells
Lacunae is connected by…
Connected by canaliculi
Osteon
Basic unit of compact bone
Trabeculae
Lattice like network of spongy bone
Ossification
An area where bone develops
Intramembranous ossification
Comes out of membrane
Endochondral ossification
Comes out of cartalege
Development steps for bone from undifferentiated cells
1- mesenchymal cells of embryo gather in specific areas
2- cells begin to differentiate into various cells
3- osteoblasts secrete osteoid
Perichondrium forms
Layer of cartilage
Calcium
Can only be obtained from diet
Requires vitamin D to disperse
What three types of muscle tissue
Skeletal
Cardiac
Smooth
Excitability
Plasma membranes can change their electrical state
Elasticity
Muscle fibers recoil back due to elastic fibers
Contractility
Allows muscle tissue to pull on attachment points
Extensibility
Can stretch or extend
Epimysium muscle
Outermost, wraps around entire muscle
Perimysium muscle
Muscle fibers arrange into individual bundles
Endomysium muscle
Covers each muscle fiber
Tendons and aponeurosis are….
The combination of all connective tissues
Sarcomere ( muscle fiber)
Functional unit of muscle
Sarcolemma (muscle fibers)
Plasma membrane
Sarcoplasm ( muscle fibers)
Cytoplasm
Sarcoplasmic reticulum (muscle fiber)
Specialized smooth ER that surrounds each myofibril
Action
Thin filament
Myosin
Thick filament
How does a muscle contract
It begins with an action potential at the neuromuscular junction
For a muscle to contract it must?
First be excited by getting the electrical signal from the nerve to the muscle
Tropomyosin
Prevents action-myosin interaction
Troponin
Binds tropomyosin to G-actin
Muscle contraction (skeletal muscle)
Contraction cycle begins Active-site exposure Cross-bridge formation Myosin head pivoting Cross-bridge detachment Myosin reactivation
Skeletal muscle relaxation
Ca2 + concentrations fall
Ca2+ detaches from troponin
Active sites re-covered by tropomyosin
Rigor mortis
A fixed muscular contraction after death
Muscle twitch
A single contraction
Muscle contraction
Many repeated stimuli
What supplies the energy for muscle contraction
ATP
ATP creatine phosphate
Stores energy in phosphate bonds,
Acts as an energy reverse for quick ATP production,
Only provides about 15 seconds worth of energy
ATP glycolysis
After creatine phosphate is depleted, glycolysis takes over
ATP aerobic respiration
Breakdown of glucose in the presence of oxygen in mitochondria
Muscle fatigue
When muscles can no longer contract in response to signals
Cardiac muscle
Highly coordinated to produce simultaneous contractions
Smooth muscle
Found in walls of many organs