Test 2 Flashcards
Cardiovascular and Respiratory
Chlorthalidone
Thiazide Diuretic
Indapamide
Thiazide Diuretic
Amiloride
Non-Aldosterone Antagonist/ K-sparing Diuretic
Triamterene
Non-Aldosterone Antagonist/ K-sparing Diuretic
Spironolactone
Aldosterone Antagonist/ K-sparing Diuretic
Epleronone
Aldosterone Anatagonist/ K-sparing Diuretic
Nadolol, Propanolol, Pindolol, Timolol
Non-selective Beta Blockers
Atenolol, Metoprolol, Esmolol, Bisoprolol
Cardioselective Beta-Blockers- only bind to B-1 receptors
Labetolol, Carvedilol
Alpha-beta adrenergic antagonist- block B-1, B-2, and Alpha 1 receptors
Aliskiren
Renin Inhibitor
Amlodipine, Felodipine,
DHP Calcium Channel Blockers
Diltiazem, Verapamil
Non-DHP Calcium Channel Blockers
Methyldopa, Clonidine
Centrally-acting Alpha 2 Agonists
Hydralazine, Minoxidil, Sodium Nitroprusside
Vasodilators
“-statin”
HMG COA Reductase Inhibitors
Gemfibrozil, Micronized Fenofibrate, Clofibrate
Fibrates: Fibric Acid derivatives
Cholestyramine, Colestipol, Colesevelam
Bile Acid Sequestrants
Ezetimibe
Selective cholesterol-absorption inhibitor (best used w/ statins)
Alirocumab, Evolocumab
PCSK9 Inhibitors
“-pril”
ACE Inhibitors
“-sartan”
Angiotensin II Receptor Blockers
Warfarin (Coumadin), Factor Xa Inhibitors (-aban), Direct Thrombin Inhibitors (Dabigatran)
Oral Anticoagulants
UH, LMWH, Fondaparinux, Direct Thrombin Inhibitors (Bivalirudin, Argatroban, & Desirudin
Parenteral Anticoagulants
“-aban”
Direct Oral Anticoagulants, Factor Xa Inhibitors
Dabigatran
Direct Oral Anticoagulant, Direct Thrombin Inhibitor (only oral DTI)
Bivaluridin, Argatroban, Desirudin
Parenteral Direct Thrombin Inhibitors
Class I:
A: Quinidine, Procainimide, disopyramide
Sodium Channel Blocker, lengthen the duration of action potential
Class I:
B: Lidocaine, Mexiletine, & Phenytoin
Sodium Channel Blocker, shorten the duration of action potential
Class I:
C. Encainide, Lorcainide, Flecainide, & Propafenone
Sodium Channel Blocker, minimally increase action potential
Class II: propanolol, metoprolol, sotalol
Beta Blockers, reduce the adrenergic activity in the heart
Class III: Amiodarone, Bretylium
Potassium-Channel Blockers, prolong effective refractory period and reduce speed of conduction
Class IV: Verapamil, Diltiazem, Bepridil
Calcium Channel Blockers, block the influx of calcium, reduce contractility (negative inotropism), decrease SA and AV node conduction
Significantly reduce afterload but little effect on preload
Class 1A Quinidine is used for?
Atrial or Ventricular Dysrhythmias
Class 1A Procainamide is used for?
Restore sinus rhythm in WPW syndrome, Ventricular Arrhythmias
Class 1B Lidocaine, Mexiletine is used for?
Ventricular Arrhythmias ONLY
Class 1C Flecainide, Propafenone is used for?
Atrial or Ventricular Dysrhythmias when other agents fail
restrict use to life threatening ventricular arrhythmias not for chronic atrial fib, can be used on paroxysmal atrial fib
Class II Beta Blockers are used for?
Indicated for use in patients with paroxysmal, persistent, or permanent AF and Atrial Flutter
Ongoing management in patients with symptomatic SVT
often first line antiarrhythmic agent
Class III Amiodarone is used for?
Ventricular Fibrillation, Ventricular Tachycardia, Atrial Fibrillation, Atrial Flutter
Class IV Verapamil & Diltiazem is used for?
Useful for ventricular rate control in both acute and chronic AF and atrial flutter
Adenosine is used for?
Supraventricular Arrhythmias
Digoxin is used for?
Not first line
combination of digoxin and BB or non-dhp CCB is reasonable for rate control in patients w/ AF and HF
