Test 2 Flashcards

Cardiovascular and Respiratory

1
Q

Chlorthalidone

A

Thiazide Diuretic

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2
Q

Indapamide

A

Thiazide Diuretic

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3
Q

Amiloride

A

Non-Aldosterone Antagonist/ K-sparing Diuretic

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4
Q

Triamterene

A

Non-Aldosterone Antagonist/ K-sparing Diuretic

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5
Q

Spironolactone

A

Aldosterone Antagonist/ K-sparing Diuretic

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6
Q

Epleronone

A

Aldosterone Anatagonist/ K-sparing Diuretic

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7
Q

Nadolol, Propanolol, Pindolol, Timolol

A

Non-selective Beta Blockers

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8
Q

Atenolol, Metoprolol, Esmolol, Bisoprolol

A

Cardioselective Beta-Blockers- only bind to B-1 receptors

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9
Q

Labetolol, Carvedilol

A

Alpha-beta adrenergic antagonist- block B-1, B-2, and Alpha 1 receptors

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10
Q

Aliskiren

A

Renin Inhibitor

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11
Q

Amlodipine, Felodipine,

A

DHP Calcium Channel Blockers

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12
Q

Diltiazem, Verapamil

A

Non-DHP Calcium Channel Blockers

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13
Q

Methyldopa, Clonidine

A

Centrally-acting Alpha 2 Agonists

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14
Q

Hydralazine, Minoxidil, Sodium Nitroprusside

A

Vasodilators

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15
Q

“-statin”

A

HMG COA Reductase Inhibitors

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16
Q

Gemfibrozil, Micronized Fenofibrate, Clofibrate

A

Fibrates: Fibric Acid derivatives

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17
Q

Cholestyramine, Colestipol, Colesevelam

A

Bile Acid Sequestrants

18
Q

Ezetimibe

A

Selective cholesterol-absorption inhibitor (best used w/ statins)

19
Q

Alirocumab, Evolocumab

A

PCSK9 Inhibitors

20
Q

“-pril”

A

ACE Inhibitors

21
Q

“-sartan”

A

Angiotensin II Receptor Blockers

22
Q

Warfarin (Coumadin), Factor Xa Inhibitors (-aban), Direct Thrombin Inhibitors (Dabigatran)

A

Oral Anticoagulants

23
Q

UH, LMWH, Fondaparinux, Direct Thrombin Inhibitors (Bivalirudin, Argatroban, & Desirudin

A

Parenteral Anticoagulants

24
Q

“-aban”

A

Direct Oral Anticoagulants, Factor Xa Inhibitors

25
Q

Dabigatran

A

Direct Oral Anticoagulant, Direct Thrombin Inhibitor (only oral DTI)

26
Q

Bivaluridin, Argatroban, Desirudin

A

Parenteral Direct Thrombin Inhibitors

27
Q

Class I:
A: Quinidine, Procainimide, disopyramide

A

Sodium Channel Blocker, lengthen the duration of action potential

28
Q

Class I:
B: Lidocaine, Mexiletine, & Phenytoin

A

Sodium Channel Blocker, shorten the duration of action potential

29
Q

Class I:
C. Encainide, Lorcainide, Flecainide, & Propafenone

A

Sodium Channel Blocker, minimally increase action potential

30
Q

Class II: propanolol, metoprolol, sotalol

A

Beta Blockers, reduce the adrenergic activity in the heart

31
Q

Class III: Amiodarone, Bretylium

A

Potassium-Channel Blockers, prolong effective refractory period and reduce speed of conduction

32
Q

Class IV: Verapamil, Diltiazem, Bepridil

A

Calcium Channel Blockers, block the influx of calcium, reduce contractility (negative inotropism), decrease SA and AV node conduction
Significantly reduce afterload but little effect on preload

33
Q

Class 1A Quinidine is used for?

A

Atrial or Ventricular Dysrhythmias

34
Q

Class 1A Procainamide is used for?

A

Restore sinus rhythm in WPW syndrome, Ventricular Arrhythmias

35
Q

Class 1B Lidocaine, Mexiletine is used for?

A

Ventricular Arrhythmias ONLY

36
Q

Class 1C Flecainide, Propafenone is used for?

A

Atrial or Ventricular Dysrhythmias when other agents fail
restrict use to life threatening ventricular arrhythmias not for chronic atrial fib, can be used on paroxysmal atrial fib

37
Q

Class II Beta Blockers are used for?

A

Indicated for use in patients with paroxysmal, persistent, or permanent AF and Atrial Flutter
Ongoing management in patients with symptomatic SVT
often first line antiarrhythmic agent

38
Q

Class III Amiodarone is used for?

A

Ventricular Fibrillation, Ventricular Tachycardia, Atrial Fibrillation, Atrial Flutter

39
Q

Class IV Verapamil & Diltiazem is used for?

A

Useful for ventricular rate control in both acute and chronic AF and atrial flutter

40
Q

Adenosine is used for?

A

Supraventricular Arrhythmias

41
Q

Digoxin is used for?

A

Not first line
combination of digoxin and BB or non-dhp CCB is reasonable for rate control in patients w/ AF and HF