Test 2 Flashcards
Integumentary System
Consists of Skin, Har, nails and associated glands. Body’s largest and heaviest organ (8%). Consists of 2 layers. Stratified squamous epithelium called epidermis and a deeper connective tissue called dermis.
6 Functions Of Skin
1) Resistance to trauma and infection
2) Barrier to water and UV rays
3) Vitamin D Synthesis
4)Sensation
5) Thermoregulation
6) Non Verbal Communication
Epidermis
Keratinized stratified squamous epithelium. Surface consists of dead cells packed with tough protein keratin. Lacks blood vessels and depends on diffusion of nutrients from underlying connective tissue. Five types of Cells.
Keratinocytes
Great majority of epidermal cells. Synthesize keratin.
Stem Cells
Undifferentiated cells that divide and give rise to the keratinocytes. Found in Stratum Basale.
Melanocytes
Synthesize brown to black pigment melanin. Found in stratum Basale.
Tactile Cells
Receptors for touch. Found in stratum Basale.
Dendritic Cells
Immune cells that originate in bone marrow but migrate to epidermis. Stand guard against toxins to alert immune system. Found in Spinosum and Granulosum.
Stratum Basale
Deepest layer of epidermis. Consists of single layer of cuboidal to low columnar stem cells and keratinocytes resting on the basement membrane. As stem cells divide, give rise to keratinocytes that migrate up.
Stratum Spinosum
Consists of several layers of keratinocytes. In most places, thickest stratum except palms and soles. Deeper cells continue dividing but as pushed up they cease. Instead, produce more keratin filaments which causes cells to flatten.
Stratum Granulosum
Consists of 3-5 layers of flat keratinocytes. More in thick skin than thin.
Stratum Lucidum
Thin zone superficial to granulosum, only in thin skin. Keratinocytes densely packed with clear protein eleidin. Cells have no nuclei or organelles.
Stratum Corneum
Consists up to 30 layers dead skin
Stratum Corneum
Consists of up to 30 layers dead skin. Resistant to abrasion, penetration and water loss.
Dermis
Composed mainly of collagen but also contains elastic and reticular fibers, fibroblasts. Supplied with blood vessels, glands and nerve endings. Hair and nails embedded in dermis. Face skeletal muscles attach for expressions. 2 zones.
Papillary Layer 1
Thin zone of areolar tissue. Loosely organized tissue allows for mobility of leukocytes. Packed with small blood vessels.
Reticular Layer 2
Deeper and much thicker. Dense irregular conncective tissue. Striae is formed.
Hypodermis
Packed with more areolar and adipose tissue. Subcutaneous fat.
Melanocytes
produce melanin that accumulates in keratinocytes. Eumelanin is brownish black. Pheomelanin is reddish yellow. Same amount of melanin in most people.
Friction Ridges
markings on the fingertips. Form during fetal development.
Mole
Nevus
Hemangioma
Birthmark