Test 2 Flashcards
evaluation of psychotic patient
- history (talk to family)
- mental state to establish baseline
- physical exam
- labs
- imaging (at least one head CT)
positive schizophrenia symptoms
- have to have at least 2*
- respond to antipsychotic Rx*
- disorganized speech
- bizarre behavior
- delusions
- hallucinations
- thought disorders
negative schizophrenia symptoms
- alogia (sparse speech)
- affective flattening
- anhedonia
- asociability
- apathy
- attention impairement
- less responsive to Rx*
delusion
a fixed false belief with evidence that the belief is false
hallucination
- vivid perceptual experience that occurs in absence of valid sensory stimulus
- visual, olfactory, and tactile need medical causes ruled out
catatonia
- abnormal motor behavior and periods of extreme hyperactivity and hypoactivity
- waxy flexibility
schizophrenia diagnostic criteria
- 2 characteristic symptoms of psychosis (hallucinations, delusions, disorganized speech, disorganized behavior, negative symptoms)
- lasts at least 6 months with 1 month of characteristic symptoms
- social and/or occupational dysfunction
- exclude other disorders
schizophreniform disorder
- one to six months of symptoms
- social/occupational impairment not required
schizoaffective disorder
- psychotic symptoms plus prominent mood symptoms
- two week period of psychotic symptoms without mood symptoms
delusional disorder
- delusions for at least 1 month
- no other criteria met
brief psychotic disorder
- one of the characteristic symptoms
- time range one day to one month
substance induced psychotic disorder
-hallucinations or delusions during or within one month of substance abuse
acute psychosis treatment
- one of haldol, geodon, zyprexa (or other 2nd generation antipsychotic)
- plus ativan
- sometimes benadryl or vistaril
“B-52”
long term schizophrenia treatment
- haldol first line for typical
- clozapine most effect for atypical but not used first line due to agranulocytosis
depressive type schizoaffective treatment
- 2nd generation antipsychotic
- antidepressant as adjunct
bipolar type schizoaffective long term treatment
- 2nd generation antipsychotic
- mood stabilizer as adjunct
treatment of dystonia
- cogentin
- benadryl
akathisia treatment
propranolol
benzodiazepine
benzotropine (cogentin)
tardive dyskinesia treatment
ingrezza (valbenazine)
insight oriented psychoanalysis
- increase patient’s understanding of neurosis
- uncover repressed memories
- long term
supportive psychotherapy
- therapeutic relationship for emotional support
- acute crisis
- patients with low ego strength
- vulnerable patients
cognitive behavioral therapy
- indicated for anxiety and mood disorders
- focus on patient’s maladaptive thinking
- learn new thought patterns and behaviors
dialectical behavioral therapy
- indicated for borderline personality disorder
- increase interpersonal skill and emotional regulation
- decrease self destruction
group therapy
- family
- couples
- self help
- group patients with similar diagnosis
denial
- primitive defense
- refusal to accept reality or fact
regression
- primitive defense
- reversion to earlier stage of development
acting out
- primitive defense
- extreme behavior to express thoughts or feeling
dissociation
- primitive defense
- person loses track of time and/or person and instead finds another representation of their self to continue in the moment
- common with child abuse history
compartmentalization
- primitive defense
- lesser form of dissociation where aspects of a person’s life are separated
projection
- primitive defense
- misattribution of a person’s thoughts, feelings, or impulses onto another person
repression
- intermediate defense
- unconscious blocking of unacceptable thoughts, feelings, or impulses
displacement
- intermediate defense
- redirecting of thoughts, feelings, or impulses directed at one person/object but taken out on another person/object
intellectualization
- intermediate defense
- overemphasis on thinking when confronted with an unacceptable impulse, situation, or behavior without employing any emotions
rationalization
- intermediate defense
- offering a different explanation for one’s perceptions or behaviors in the face of a changing reality
undoing
- intermediate defense
- attempt to take back an unconscious behavior or thought that is unacceptable or hurtful
sublimation
- mature defense
- channeling of unacceptable thoughts, impulses, and emotions in to favorable ones
compensation
- mature defense
- psychologically counterbalancing perceived weaknesses by emphasizing strengths in other areas
assertiveness
- mature defense
- strike a balance to speak up for themselves, express needs/opinions respectfully, and listen when spoken to
prescribing for pregnant population
- 1st: avoid/minimize medications
- 2nd: treat the mother
- evaluate risk/benefit with patient and OB team
prescribing for geriatric population
- start low and go slow
- first think drugs as cause of symptoms when diagnosing
- avoid polypharmacy
- decreased volume of distribution
- decreased metabolism
- increased AE sensitivity
SSRIs drugs
“Effective For Sadness Panic Compulsions”
- citalopram (celexa)
- escitalopram (lexapro)
- fluoxetine (prozac)
- fluvoxamine (paxil)
- sertraline (zoloft)
- paroxetine (paxil)
SSRI+ drugs
vilazadone (viibryd)
vortioxetine (trintellix)
SSRI and partial serotonin agonist
SNRI drugs
desvenlafaxine (pristiq)
duloxetine (cymbalta)
venlafaxine (effexor)
also used for peripheral pain and neuropathy
SSRI side effects
- GI upset
- sexual dysfunction
- activation/akathisia (will go away)
- mania
- SI in younger patients
- serotonin syndrome
serotonin syndrome
- potentially fatal
- can be caused by combining an SSRI/SNRI with an MAOI (should separate by 5 weeks)
- takes 24-48 hours to develop
- variable mental status
- increased muscle tone
- HTN, tachycardia, tachypnea, fever
- hyperreflexia
- mydriasis
- increased bowel sounds
serotonin syndrome treatment
- stop all serotonergic drugs
- supportive care to stabilize vitals
- benzo for sedation, relaxation
- serotonin antagonist for severe cases
bupropion (wellbutrin)
- atypical antidepressant
- do not use in patient with seizure history
- often used as adjunct with SSRI
mirtazapine (remeron)
- atypical antidepressant
- also used as sleep aid
- AE: weight gain
trazodone (desyrel)
- atypical antidepressant
- also used as sleep aid
- AE: priaprism
esketamine (spravato)
- used for treatment resistant depressant as an adjunct to other antidepressants
- patients monitored for 2 hours after dose for hallucinations
- not used in pregnancy
- AE: dissociative and perceptual changes, derealization, depersonalization, HTN
tricyclics
- 2nd/3rd line for Rx resistant depression
- OD causes fatal cardiac arrhythmias
- be aware of suicidal ideations when prescribing
- amitriptyline, clomipramine
tricyclic side effects
- cardiac toxicity (LBBB, V-tach)
- anticholinergic effects
MAOI
- use is very uncommon
- avoid tyramine containing foods due to HTN crisis