Test 1 Histology Flashcards

1
Q

What is the flow of the heart?

A

superior/inferior vena cava - right atrium- tricuspid valve- right ventricle- pulmonary valve- pulmonary artery- lungs- left atrium- left ventricle- aorta- systemic

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2
Q

What are the layers of the heart from outside to inside?

A

fibrous pericardium- serous pericardium- space- epicardium- myocardium- endocardium- heart chamber

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3
Q

What is pericarditis?

A

inflammation of the pericardium

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4
Q

What are the possible causes of pericarditis?

A

systemic inflammatory disorders (lupus or rheumatoid arthritis), injury to heart or chest, kidney failure, AIDS, tuberculosis, and cancer

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5
Q

What are the possible outcomes of pericarditis?

A

resolve itself, progress to constrictive pericarditis, or cardiac tamponade

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6
Q

What is cardiac tamponade?

A

pressure on the heart that occurs when blood or fluid builds up in the pericardial sac

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7
Q

What are the causes of cardiac tamponade?

A

pericarditis, wounds to the heart, dissecting aortic aneurysm, heart attack (accuse MI)

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8
Q

What do the specific atrial granules from the atrial myocytes secrete?

A

atrial natriuretic factor and brain natriuretic factor

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9
Q

What causes the dark lines in intercalated discs?

A

fascia adherens

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10
Q

What is the subendocardial layer made up of?

A

loose CT with blood vessels that is continuous with the endomycium

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11
Q

Where is the Bundle of His located?

A

membranous part of IV septum.

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12
Q

Tricuspid valve separates what?

A

right atrium from right ventricle

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13
Q

Bicuspid valve separates what?

A

left atrium from right ventricle

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14
Q

Aortic valve separates what?

A

left ventricle from aorta

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15
Q

Pulmonary valve separates what?

A

right ventricle from pulmonary artery

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16
Q

The spongiosa of the valves is made up of what?

A

collagen, elastic fibers and proteoglycans

17
Q

The fibrosa of the valves is made up of what?

A

dense regular CT

18
Q

What is regurgitation of the valves?

A

when a valve doesn’t close tightly resulting in back flow, most often due to prolapse.

19
Q

Prolapse mainly affects what valve?

A

Mitral valve

20
Q

What is stenosis?

A

when the flaps of a valve thicken/stiffen or fuse together preventing the heart valve from fully opening.

21
Q

What is the conducting pathway of the heart?

A

SA node- AV node- Bundle of His- Purkinje fibers

22
Q

Where is the SA node located?

A

in the wall of the right atrium as it meets superior vena cava

23
Q

Where is the AV node located?

A

wall of the right atrium

24
Q

What defines Purkinje fibers?

A

larger than ventricular muscle cells, myofibrils located in periphery of cell, intercalated disks, large amounts of glycogen.

25
Q

What is chronotropic effect?

A

substance that changes heart rate

26
Q

What is a inotropic effect?

A

substance that changes force of contraction

27
Q

What are the substances of sympathetic innervation?

A

norepinephrine, epinephrine, caffeine

28
Q

What are the substances of parasympathetic innervation?

A

Ach, propranolol, Calcium channel blockers

29
Q

Where is the heart located?

A

space formed by the sternum, vertebral column, diaphragm and lungs

30
Q

What causes coronary artery disease?

A

plaque buildup in the walls of the coronary arteries

31
Q

What is MI?

A

irreversible necrosis of heart muscle secondary to prolonged ischemia

32
Q

What is the purpose of the spongiosa in valves?

A

dampen vibrations associated with closing of the valves

33
Q

What is the spongiosa in the aortic/pulmonary valves known as?

A

arterialis

34
Q

What is the spongiosa in the mitral and tricuspid valves known as?

A

auricularis

35
Q

Where do parasympathetic fibers of the heart originate?

A

vagus nerve

36
Q

Where do sympathetic fibers of the heart originate?

A

lateral horns at T1 to T6 of the spinal cord

37
Q

Where are cardio baroreceptors located?

A

carotid sinus and aortic arch

38
Q

Where are cardio chemoreceptors located?

A

carotid and aortic bodies located at bifurcation of common carotid and aortic arch.