Test 1- Endocrine/digestive System Flashcards
Static
Not moving
What are 5 things needed to live?
Nutrients, oxygen, water, right temp (98.4) and right pressure
Dynamic
Moving. Homeostasis is dynamic
Negative feedback
Any change that is opposite to initial change. Most systems in body are negative feedback
Positive feedback
If it increases, then further increases
If it decreases, then it further decreases
Anything in same direction aka domino effect
What are examples of negative feedback including glucagon and insulin?
If you have high blood sugar your body releases insulin to bring it back down and return to homeostasis.
If you have low blood sugar your pancreas makes glucagon which stimulates the liver to break it down into glucose which then increases blood sugar and returns to homeostasis
Normal blood glucose level is?
90 mg to 100 ml
Affrent
Input info sent by receptor and sends them along
Efferent
Output info sent to effectors to make change
Example of positive feedback
Using platelets to clot an open vessel wall. Clotting attracts more platelets for more clotting to take place. Happens until vessel is sealed
Endocrine system is what type of system
Discontinued bc organs are placed all over body not attached.
Endocrine system organs
Are ductless glands with no tubes. Secrete hormones only. Blood is the carrier of all hormones
Autocrine
When a cell secretes a hormone and then shows it on itself (same cell)
Paracrine
When a cell transfers to a tissue in the same area
Endocrine
When a cell transfers to anywhere
What are the 2 types of hormones?
Amino acid based and steroid hormones. They are highly specific. Hormones are also know. As chemical messengers
Pineal gland
P- shaped, rich with calcium salts (brain sand)
Used as reference in x-Ray to find other tissues
Releases melatonin a wonder drug
Circadian rhythm
Tells you to sleep at night and stay awake in the day using melatonin
Circannual rhythm
Changes annually
Parapsychology
Involved in telekinesis and 6th sense because of pineal gland
Hypothalamus gland
Master gland of endocrine system
Direct activation
All steroid hormones go straight to nucleus
Signaling activation
Amino acids
Thyroxine
Amino acid hormone but the only amino acid that can go directly into cell and activate it (direct activation)
Permissional hormones
For one hormone to act you need another hormone. Asking permission
Synergistic hormones
Work together
Antagonistic
Working against each other
Hormones can be released 3 diff ways
Humoral, neural and hormonal
Pituitary gland
Hypophysis. Not master gland anymore. Made up of anterior and posterior lobe. Tsh tells thyroid to secrete thyroxine
Anterior lobe
Adenohypohysis. More dense. Thicker bc secretes more hormones. Tsh fsh lh acth gh prl. Growth hormone and prolactin are tropical used as sex hormones
Growth hormone
Hypo secretion ( not enough) you get dwarfism. Hyper secretion (too much) you get gigantism or acromegaly in adults
Thyroid stimulating hormone
Thyroxine is secreted by thyroid under tsh.
Hypo- cretinism kids. Myxedema adults. -mentally challenged.
Hyper- hyperthyroidism constantly tired
Adrenocorticotropic hormone
Stimulates adrenal cortex. Hypo-rare. Hyper- cushiness disease-obesity in torso
Follicle stimulating hormone (fsh)
Stimulates follicles.
Hypo- can’t make eggs/sperm failure sex maturation
Hyper- 2 eggs at once fertilized
Luteinizing hormone (lh)
Same as fsh. Too little cant make eggs/ sperm. Too much makes too many (Twins)
Prolactin (prl)
Hypo- poor milk production
Hyper- galactorrhea- too much milk secretion enlarged breasts
Gynecomastia- men
Oxytocin (posterior)
Cuddle hormone. Increase makes men emotional. In women contracts uterus during birth
Antidiuretic hormone (adh) posterior (vasopressin)
Stops urination. Alcohol stops secretion of adh so u pee a lot.
Hypo- diabetes insipidus- constant thirst/ peeing
Hyper-in appropriate adh secretion
Thyroid gland
Secretes calcitonin and thyroid hormone (t3 & t4)
Bilobe gland connected by isthmus
Follicles
Are filled with Colloid and cells that surround it are follicle cells which produce thyroglobulin
Follicle cells
Produce thyroglobulin
Parafollicular cell
Produce/ release calcitonin which reduces blood calcium
T3( triiodothyronine) & T4 (thyroxine)
Low secretion kids- cretinism- bulging thyroid gland
Low secretion adults- myxedema- lack of iodine leads to goiter(bulging eyes)
Calcitonin
Lowers blood calcium
Graves’ disease
Metabolic hormone. Get bc too much t3 and t4
Hashimotos
Autoimmune disease due to too much t3 and t4
Autoimmune disease
Your body starts fighting it’s antibodies with itself so it blocks thyroxine and the. U have antibodies against thyroxine
Parathyroid hormone
Increases calcium