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Organ Histo > Test 1 - chp 1 > Flashcards

Test 1 - chp 1 Flashcards

1
Q

General functions of epi

A

absorption, secretion, barrier

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2
Q

Complete basement membrane

A

basal lamina + reticular lamina

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3
Q

incomplete basement membrane

A

basal lamina only

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4
Q

Functions of CT

A

nutrition and source of defensive cells

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5
Q

zonula occludens AKA

A

tight junctions

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6
Q

zonula occludens fxn

A

strong attachment & prevent passage of materials

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7
Q

zonula adherins AKA

A

adhesion belt

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8
Q

zonula adherins consist of

A

cadherins and marginal bands

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9
Q

zonula adherins fxn

A

strong attachment, structural stability

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10
Q

macula adherens aka

A

desmosome

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11
Q

macula adherens fxn

A

strong attachment

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12
Q

gap junction

A

6 connexins in a cylinder

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13
Q

gap junction fxn

A

strong attachment, transport materials between cells

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14
Q

junctional complex order from free edge

A

zonula occludens, zonula ahderens, macula adherens

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15
Q

simple squamous locations

A

lung, bowman’s capsule, serosa

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16
Q

simple cuboidal

A

exocrine ducts, thyroid follicular cells, kidney tubules

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17
Q

simple squamous fxn

A

filter barrier, secretion

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18
Q

simple cuboidal fxn

A

absorption, secretion, barrier

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19
Q

simple columnar location

A

stomach, SI, gallbladder, larger exocrine ducts

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20
Q

simple columnar fxn

A

absorption, secretion, barrier

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21
Q

respiratory epi location

A

trachea, respiratory region/nasal cavity, bronchi

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22
Q

cell types of respiratory epi

A

goblet cells, ciliated columnar, basal

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23
Q

goblet cells fxn

A

produce mucus

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24
Q

ciliated columnar cells fxn

A

move mucus

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25
Q

basal cell fxn

A

be stem cell

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26
Q

microvilli location

A

kidney tubule cells, SI

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27
Q

microvilli fxn

A

increase SA = increase absorption

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28
Q

stereocilia location

A

epididymis and cochlear hair cells

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29
Q

cilia location

A

trachea or oviduct

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30
Q

cells with cilia

A

many mito, basal bodies block free surface= NO absorption/secretion

31
Q

glycocalyx location

A

stomach and SI

32
Q

glycocalyx fxn

A

protection and cell recognition

33
Q

stratified squamous location

A

esophagus, oral cavity, tongue, vagina

34
Q

stratified squamous fxn

A

protection in MOIST environment

35
Q

keratinized stratified squamous location

36
Q

keratinized stratified squamous fxn

A

protection in DRY environment

37
Q

layers of skin (free edge –> deepest)

A

stratum corneum, lucidum, granulosum, spinosum, basale

38
Q

stratum basale

A

1-2 layers of keratinocytes = mitotic

39
Q

stratum spinosum

A

multiple layers of “spiny shaped” keratinocytes - produce keratin

40
Q

stratum granulosum

A

2-5 layers of flattened living keratinocytes, keratin and lipid production

41
Q

stratum lucidum

A

thin layer of dead or dying keratinocytes = only THICK SKIN

42
Q

stratum corneum

A

dead cells, keratin, lipids

43
Q

stratum corneum fxn

A

prevent water loss, barrier to microbes, protect against abrasions

44
Q

melanocytes

A

protect against UV radiation, STRATUM BASALE

45
Q

Langerhans cells

A

recognize and process external antigens and APC, STRATUM SPINOSUM

46
Q

merkel cells

A

touch receptors, STRATUM BASALE

47
Q

4 cell types of skin

A

keratinocytes, melanocytes, Langerhans, merkel

48
Q

stratified cuboidal location

A

larger ducts in sweat and salivary gl

49
Q

stratified cuboidal layers

A

basal = flat, superficial = cuboid

50
Q

stratified cuboidal fxn

A

increase protection, barrier

51
Q

stratified columnar location

A

large ducts/pancreas, male urethra, conjuctiva

52
Q

stratified columnar layers

A

basal = flat/cuboid, superficial = columnar

53
Q

stratified columnar fxn

A

increase protection, transition between epi, barrier

54
Q

transitional/urinary location

A

urinary tract

55
Q

urinary fxn

A

protection, stretch, barrier

56
Q

psoriasis vulgaris

A

patchy skin lesions, accelerated keratinocyte life cycle, accumulation in st corneum

57
Q

freckles

A

spots with extra pigment, increase in melanin w/o increase in melanocyte numbers

58
Q

vitiligo

A

patches w/o melanocytes

59
Q

moles

A

discoloration due to proliferation of melanocytes

60
Q

malignant melanoma

A

melanocytes become mitotically active and invade dermis

61
Q

albinism

A

melanocytes fail to produce melanin (MC = lack tyrosinase)

62
Q

exocrine secretion of epi glands

A

product released into duct or directly onto epi surface

63
Q

merocrine/eccrine ex (MC, exocytosis)

A

goblet, salivary, pancreas, ALL kid sweat glands, many adult sweat glands

64
Q

holocrine ex (cell dies, odor)

A

sebaceous gl, tarsal gl

65
Q

apocrine ex (minimal cell damage, odor)

A

lactating mammary gl, some adult sweat gl, ceruminous gl, ciliary gl

66
Q

serous glands produce

67
Q

serous gl ex

A

pancreas, parotid gl,, chief cells in stomach

68
Q

mucus gland produce

69
Q

mucus gl ex

A

goblet, mucous cells in stomach, minor salivary gl/tongue and palate

70
Q

mixed gland produce

A

serous and mucus

71
Q

mixed glands ex

A

sublingual and submandibular salivary gl

72
Q

endocrine secretion

A

released into nearby CT for vascular dispersal to target cells/hormone

73
Q

paracrine endocrine secretion

A

signal close to target sell (hormone does not enter blood)

74
Q

autocrine endocrine secretion

A

signaling cell is its own target

Organ Histo (2 decks)

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