Test 1- Chp 1-4 Study guide Flashcards
What regulates muscle actions?
Calcium
What acts at the neuromuscular junction to excite the muscle fibers of a motor unit?
Acetylcholine
What muscle fiber types is the most beneficial for a marathon runner?
Type 1
__________ is when the actin filament at each end of the sarcomere slide inward on myosin filaments, pulling the z-lines toward the center of the sarcomere and thus shortening the muscle fiber.
Sliding filament theory
What are the 5 phases of the sliding filament theory?
- Resting please
- Excitation- contraction coupling phase
- Contraction phase
- Recharge phase
- Relaxation phase
What is the resting phase of the sliding filament theory?
Little calcium is present
Little of the myosin cross bridges are bound to actin
No tension in the muscle
What is the excitation- contraction coupling phase of the sliding filament theory?
Myosin cross bridges attach to actin
Sarcoplasmic reticulum releases calcium to bind with troponin tropomyosin shifts
Myosin head attaches to actin filament allowing flexion
What is the contraction phase of the sliding filament theory?
Energy comes from hydrolysis breakdown ATP & ADP & ATPase
ATP molecule replaces ADP on myosin cross bridge head
The head detaches from actin site and resets
What is the recharge phase of the sliding filament theory?
Binding calcium to troponin, coupling myosin cross bridge w/ actin
Cross bridge flexion, dissociation of actin and myosin,
resetting of the myosin cross bridge head is repeated over and over
What is the relaxation phase of the sliding filament theory?
Occurs when the stimulation of the motor nerves stops and the actin and myosin return to an unbound state
Calcium is pumped back to sarcoplasmic reticulum preventing the
link of action & myosin.
Role of calcium in muscle contraction
Calcium binds with troponin
Causing Tropomyosin to shift
Myosin cross bridge head attaches to actin causing contraction
Sarcoplasmic reticulum pumps calcium back inside (=relaxation)
The cytoplasm of a muscle fiber- contains protein filaments, stored glycogen, and fat particles, enzymes, mitochondria, and sarcoplasmic reticulum?
Sarcoplasm
Two types of Myofibrils that contract muscle cells?
Myosin
Actin
Myosin
Thick filament
200 myosin molecules
Cross bridges protrude away at regular intervals
Actin
Thin filament
Composed of actin, tropomyosin, troponin
Consists of two strands arranged in a double helix
The arrangement of ________and _______filaments give skeletal muscle it’s striated appearance.
Myosin and actin
Actin and myosin are organized longitudinally in the smallest contractile unit of skeletal muscle which is the__________.
Sarcomere
A___________ is the basic functional unit of a Myofibrils and the basic contractile unit of muscle.
Sarcomere
Each sarcomere has bands, lines, and zones found between each z lines. What are they?
Z-line
I-band
A-band
H-zone
What is the A-band?
Aligns with the myosin filaments
contains the region of the sarcomere that has both the actin and myosin filaments
What is the I band?
Contains the region of the sarcomere where there are only actin filaments.
Located in the middle of the I band running longitudinally
Composed of proteins and provide points of attachment and stability for the thin filaments.
Z line