Test 1 Flashcards
Diagnostic Process order
1) Identify the problem
2) Frame the differential diagnosis in a way that facilitates recall
3) Organize differential diagnosis
4) limit the differentials by using pivotal points to create a pt specific differential
5) Explore pt specific differentials - using history and physical exam findings
6) Rank the differentials using results of exploration
- select leading differential
- select must not miss
- select additional alternatives
7) Test
8) re-rank
9) Test
What is the most precise way of estimating pretest probability.
CDRs ( clinical decision rule )
which system reasoning is used based on memory
System 1
Which system reasoning is a more analytical approach
System 2
How should problem lists be organized?
Acute problems
chronic active problems
ending with inactive problems.
What are the components used for assessing pretest probability
use a validated clinical decision rule (CDR)
use prevalence data regarding the causes/etiologies of a symptom
use your overall clinical impression
probability above which the diagnosis is so likely you would treat the patient without further testing
treatment threshold
the probability below which the diagnosis is so unlikely it is excluded without further testing
test threshold
the probability of disease after the test is done
posttest probability
How likely can we “rule this in”
Sensitivity
the higher a sensitivity is (and the more symptoms/findings usually), the more likely we can
“rule in” a disease.
“rule this out”
Specificity
USPSTF levels of certainty regarding net benefit
net benefit = benefit – harm as implemented in a primary care population
Consistent results from well-designed studies in representative primary care populations that assess the effects of the preventive service on health outcomes; it is unlikely that these conclusions will change based on future studies.
USPSTF levels of certainty - High
Evidence sufficient to determine the effects of the preventive service on health outcomes, but methodologic issues such as limited generalizability, inconsistent findings, or inadequate size or number of studies exist; these conclusions could change based on future studies.
USPSTF levels of certainty - Moderate
Insufficient evidence to assess effects on health outcomes, due to limited number or size of studies, flaws in study designs, inconsistency of findings, lack of generalizability.
USPSTF levels of certainty - Low
The USPSTF recommends this service. There is high certainty that the net benefit is substantial.
Grades of recommendations - Grade A
The USPSTF recommends this service. There is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial
Grades of recommendations - Grade B
The USPSTF recommends selectively offering or providing this service to individual patients based on professional judgment and patient preferences. There is at least moderate certainty that the net benefit is small.
Grades of recommendations - Grade C
The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits.
Grades of recommendations - Grade D
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of the service. Evidence is lacking, of poor quality, or conflicting, and the balance of benefits and harms cannot be determined.
Grades of recommendations - Grade I statement
higher the specificity is, the more likely we can
“rule out” a disease
OLDCARTS
onset location duration character aggravating or associated factors relieving factors temporal factors severity
are the physiological links, predisposing factors, and complications for this disease present in the patient?
coherence
Does the suspected disease encompass all of the patients normal and abnormal findings?
Adequacy
Is it the simplest explanation of the patients findings?
crucial step bc patients must find the treatment recommendations acceptable
Parsimony
is the diagnosis confirmed by a radiographic or lab tests?
Diagnostic probability
rules of thumb that guide the inductive or inferential process of diagnostic reasoning. Generally accurate and useful rules to make the task of information gathering more manageable.
Heuristics
“Are the physiological links, predisposing factors, and complications for this process present in the patient?”
(All the things present in the disease, does the patient have symptoms?)
Coherence
“Does the suspected disease encompass all of the patient’s normal and abnormal findings?”
(Symptoms patients have…does this match the disease?)
Adequacy
when the practitioner suspects a cause of symptoms based on previous clinical knowledge, practitioner gathers relevant information at a quicker speed
Diagnostic reasoning:
form of reasoning acknowledging that there are many variables (environmental & social) present in an actual clinical situation
Clinical reasoning
PICO
Problem
Intervention/exposure
Comparison
Outcome
ratio of risk in the experimental group compared with the risk in the control group
RElative Risk
Is the difference between groups large enough to be worth achieving
Clinical versus statistical significance
odds of previous exposure in a case divided by the odds of exposure in a control patient
Odds ratio
Measure of the precision of results
Confidence Intervals (CIs)
in Confidence intervals the wider the CIs indicate a ____ _____
lower precision
what source of evidence provides sound evidence of cause and effect and can control for bias
RCTS (Randomized controlled clinical trials)
what source of evidence examines a number of valid studies on a topic and mathematically combines the results to report them as if they were one large study
meta analysis
what source of evidence is based on clinical experience, collective experience and knowledge of professional organizations
Expert opinion
what level of prevention involves activities directed at improving general well-being while also providing specific protection for selected diseases.
Primary prevention
screening, counseling or preventive medicines such as vaccines or dental sealants is what level of prevention
primary
Common model used to guide behavioral counseling (5As)
Ask about the behavior
Advise about the health risks and benefits of change
Agree to set a goal
Assist with identifying and overcoming barriers
Arrange for a follow up
what level of prevention goal is to identify and detect disease in its earliest stages before symptoms appear
Secondary prevention
What level of prevention includes
screening interventions to identify elevated BP or risk of DM with A1C measurement
secondary prevention
What level of prevention aims to improve the quality of life for people with various conditions by limiting complications and disabilities, reducing the severity and progression of disease and providing rehab therapy to maximize functionality and self-sufficiency.
Tertiary prevention
What level of prevention includes
optimizing treatment for chronic conditions such as asthma, DM, physical or cognitive disability
Tertiary prevention
what type of screening includes all members of a population
Population screening
what type of screening is more selective and focuses on a population at risk
Targeted screening
ie) STI screening in sexually active adolescents and young adults in a specific age groups
Name that Bias
Considering easily remembered diagnoses more likely irrespective of prevalence
Availability
Name that Bias
Pursuing Zebras
Base Rate Neglect
Name that Bias
Ignoring atypical features that are inconsistent with the favored diagnosis
Representativeness
Name that Bias
Seeking data to confirm, rather than refute the initial hypothesis
Confirmation Bias
Name that Bias
Stopping the diagnostic process too soon
Premature closure
What does the term Pursuing zebras mean
People ignore base rate (what is more likely) in favor of given individual information (the way someone appears)
Pt comes in with cough 1-3 weeks
myalgias
low grade fevers
what are you thinking?
Acute Bronchitis
R/o flu, Covid, Pneumonia, RSV
Etiology for Acute bronchitis
Viral
Bacterial (<10%)
Noninfectious
Impaired mentation/swallowing
elderly
intoxicated (alcoholics)
poor dentition
think…
Aspiration pneumonia
Signs and symptoms Fever cough chest pain Putrid Sputum Evolved over days not acute Involves the basal segment of lower lobes can also involve posterior segments of upper lobes
think aspiration pneumonia
productive cough crackles higher fevers may have chest pain SOB Chills could be viral or bacterial
Community acquired pneumonia
what views for chest x ray for pneumonia
PA and Lat better than AP
What are your differentials for Acute cough and congestion
Common cold Sinusitis bronchitis influenza Pertusis Pneumonia -CAP -HAP -AP -TB -PJP (fungal)
If Pneumonia develops more than 48 hours post hospital admission
Hospital acquired pneumonia
If pt develops pneumonia more than 48 hrs post intubation
Ventilator acquired pneumonia
abrupt onset myalgia diffuse pain cough rhinitis pharyngitis high fevers (peaks within 12 hours 40-41C) Rigors chills headache
Influenza
when is flu season
December - march
time line of flu
1-5 days (3 typical)
If fever is increasing gradually over several days think
bacterial pneumonia
cough rhinorrhea sore throat sneezing but does not resolve after 3-7 days may have posttussive emesis
pertussis
side note Whooping at end of cough is rare in adults
median duration of pertussis
42 days
immunocompromised diagnosed/undiagnosed HIV Progressive SOB Dry cough 1-3 weeks Often before diagnosed to aids Chest x ray shows diffuse bilat pneumonia (diffuse symmetric bilat alveolar or interstitial infiltrates cough Progressive dyspnea Lung sounds may be normal CT scan shows patchy nodular ground glass appearance
PJP (Pneumocystis jirovecii pneumonia)
Mycobacteria in upper lobes chronic cough, fever, weigh loss, night sweats economically disadvantaged nursing homes drug dependent homeless prison inmates weeks to months
TB
People at high risk for TB
HIV AIDS Alcoholics immunocompromised Cancer Diabetes ESRD Transplants Malnutrition TB previously on x ray PPD+
Fever Consolidation Xray Lower middle lobes PPD may be negative may resolve on its own
Primary TB
Increased risk first 2 years
decline immune fx
typical tb symptoms
progresses unless pt is tx
Reactivated TB
Associated with at least 3 of the following:
- Easy fatigability
- Feeling restless or on edge
- Trouble concentrating
- Irritability
- Muscle tension
- Sleep disturbance
Daily functioning and performance is affected.
Symptoms cannot be explained by another psychiatric or medical condition.
Generalized anxiety disorder
Intense fear of social situations
Lifetime prevalence: 13%, 12-month prevalence: 7.4%
Social Anxiety disorder
Episodic attacks not brought on by a specific trigger
Characterized by an abrupt surge in fear or discomfort, peaking within a few minutes, accompanied by at least 4 of the following symptoms:
- Sweating
- Trembling or shaking
- Shortness of breath or feeling of smothering
- Chest pain or discomfort
- Feelings of choking
- Nausea or abdominal discomfort
- Feeling dizzy, lightheaded or faint
- Chills or heat sensations
- Paresthesias
- Feeling of feeling disconnected
- Fear of losing control
- Fear of dying
Lifetime prevalence: 6.8%, 12-month prevalence: 2.4%
Panic Disorder
Metabolic: Decreased metabolism that can lead to weight gain, cold intolerance, and increased total and low-density lipoprotein (LDL) cholesterol (due to decreased clearance)
Cardiac: Reduction in myocardial contractility and heart rate
Skin: Nonpitting edema, due to accumulation of glycosaminoglycans; dry skin; coarse, fragile hair
Central nervous system: fatigue, delayed relaxation phase of the deep tendon reflexes
Pulmonary: hypoventilation seen with severe hypothyroidism
Gastrointestinal: reduced intestinal motility causes constipation
Reproductive: menstrual abnormalities, reduced fertility, increased risk of miscarriage
Hypothyroidism
Labs for Hypothyroidism
TSH and free T4
screening questions for Insomnia
Difficulty initiating sleep, staying asleep, or both?
Early awakening?
Nonrestorative sleep?
Daytime consequences? (Lack of daytime fatigue or sleepiness suggests the insomnia is not clinically significant.)
Frequency and duration?
follow up questions for insomnia
Precipitating events, progression, ameliorating or exacerbating factors?
Sleep-wake schedule?
Cognitive attitude toward sleep?
Negative expectations regarding the ability to sleep and distortions about the effects of insomnia lead to perpetuation of the insomnia.
Attitudes toward previous treatments are also important.
Psychiatric disorder present?
Substance misuse or medication use?
Medical illness with nocturnal symptoms?
Symptoms of sleep apnea, restless legs? (See discussion below.)
complain of daytime sleepiness or fatigue. Bed partners often note snoring or actual apneic episodes. Most patients are obese.
obstructive sleep apnea
obstructive sleep apnea is more common in what gender?
men
Is obstructive sleep apnea more common pre or post menopausal
post menopausal
what questions would you ask about fatigue for a focused history and why
Can you tell me what you mean by fatigue?
How old are you?
Do you notice other symptoms with feelings of fatigue?
what are some other things that get confused with fatigue?
Weakness
Frailty
frailty can be measured based on the presence of 5 symptoms
unintentional weight loss slow mobility weakness decreased reduced activities fatigue
Frailty increases the risk for
falls
5 key questions to tell if fatigue is physiologic?
Lifestyle habits? (exercise and diet) Sleep pattern? Do you require naps? how often? Do you feel rested when you wake up in the morning? Last menstrual period?
adequate amount of sleep for adults
6-8 hours
adequate amount of sleep for adolescents
8-9 hours
adequate amount of sleep for children
10 hours
sleep pattern related to depression
early-morning wakening and excessive sleeping during the day
Men over 50 with fatigue due to nocturia associated with
BPH
last normal menstrual period might tell us what about fatigue
early sign of pregnancy
symptom after childbirth
associated with menopause
perimenopausal adults as a r/o disrupted sleep due to hot flashes
what might finding out if someone practices safe sex tell us about fatigue
may be the initial and most prominent symptom of hepatitis, HIV, AIDS
What might finding out if someone takes medications have to do with fatigue
May be a side effect.
most common drugs that cause fatigue
antihypertensive drugs cardiovascular meds psychotropic meds opiates sedatives antihistamines
What will asking about drinking alcohol tell us about fatigue
Alcohol abuse and use of recreational drugs may be overlooked as a cause of chronic fatigue in adolescents and school age children.
usually alcohol or marijuana
useful screening tool to assess for alcohol abuse
CAGE questionnaire
what does appetite tell us about fatigue
increased appetite may indicate hypoglycemia or hyperglycemia
increased thirst - hyperglycemia
decreased appetite - infectious process
What does weight loss tell us about fatigue
weight loss - malignancy, infection, poor nutrition r/t depression or lack of info on a healthy diet
weight loss of greater than 10lbs in the past year and may be associated with other signs and symptoms
unintentional weight loss
what will joint tenderness or pain tell us about fatigue
In children with Juvenile RA - severe fatigue
young and middle aged patients - can involve multiple tender points on the body that are over joints
Increased urination and fatigue
Diabetes mellitus (esp type 2) often presents with fatigue along with Polydipsia, polyphagia and polyuria
Fatigue with specific symptoms that worsen over time such as dry skin, nails
Hypothyroid
Fatigue with shortness of breath with exertion or when laying flat
heart failure
what does fatigue have to do with where you work
occupational exposure - heavy metals and pesticides may cause fatigue and other neurologic symptoms
military returning from combat zones from unknown cause
what does fatigue have to do with if they have been camping
lyme disease is carried by the deer tick. They may present with weeks of malaise and chronic fatigue before any skin manifestations appear
fatigue that has a slow and progressive onset could be associated with ______
metabolic causes
What timeline is considered significant fatigue
greater than 2 weeks
what type of fatigue is usually worse in the morning
psychological fatigue
what will help relieve psychological fatigue
physical activity
what type of fatigue is not associated with intensity or duration of activity and is not relieved with rest or sleep
organic fatigue
why would you ask if they were a caregiver if they are having fatigue
Burnout
why would you ask if you or anyone in your family has a problem with anxiety or depression for someone with fatigue
children who have family members with depression are at a greater risk for depression.
Generally the first episode of major depression occurs between the ages of —– and effects ____-
20 and 30 and effects women and transgender individuals more often then men
cc - fatigue
fever
inflammation or infection
CC fatigue
elevated HR
anxiety
anemia
dehydration
hyperthyroidism
CC fatigue
abnormal BMI
poor nutritional status
cardiovascular risk
cc fatigue
coarse, dry hair and skin
thickening of nails
hypothyroidism
cc fatigue
fine, limp hair
warm skin
hyperthyroidsim
cc fatigue
faint maculopapular rash
mononucleosis
CC fatigue
macular lesion with a clear center
lyme disease
cc fatigue
atrophic skin of the lower extremities
arterial insufficiency and underlying areriovascular disease
cc fatigue
swelling of ankles
varicose veins
skin ulcers
venous stasis
CC fatigue
evidence of nail biting
self inflicted excoriation lesions
Anxiety disorders
CC fatigue
petechiae on the palate
mononucleosis
CC fatigue
dry, cracked, ulcerated mucosa
nutritional deficiency or dehydration
CC fatigue
audible third or fourth heart sounds (S3, S4) in an adult
Heart failure
cc fatigue
increased AP diameter of the thorax
COPD
CC fatigue
Bilateral basilar rales
Congestive heart failure
Most pneumonia is on what sides
unilaterally
Barely audible breath sounds are associated with
COPD
CC fatigue
generalized symmetrical abdominal distension
obesity
enlarged organs
fluid (ascites)
gas
CC fatigue
concave contour of abdomen
dehydration or malnutrition
CC fatigue
a change in deep tendon reflexes may indicate
thyroid dysfunction
CC fatigue
diet history shows inadequate dietary intake of iron
Anemia
Pt reports cold intolerance, constipation, weight gain, hoarseness, depression, fatigue
physical exam shows bradycardia, dry skin, generalized edema, delayed recovery of deep tendon reflexes.
Hypothyroidism (myxedema)
Pt has increased sweating, heat intolerance, weight loss, irritability, disturbed sleep, menstrual irregularity.
Physical exam shows tachycardia, a-fib, tremor, warm moist skin, lid lag, exophthalmos
Hyperthyroidism (Graves disease)
What antihypertensive med is often associated with fatigue
B blockers
associated with dyspnea, orthopnea, paroxysmal nocturnal dyspnea, peripheral edema, weight gain, cough with forthy sputum, palpitations and fatigue
heart failure
gradual onset of low grade fever sore throat posterior cervical lymphadenopathy fatigue malaise
mononucleosis
malaise fatigue flulike symptoms abd pain arthralgia aversion to smoking
hepatitis
occurs most often in women 20-50
chronic pain and stiffness of trunk and extremities esp in neck, shoulders, low back and hips
fatigue, headaches, sleep disturbance, bowel irritability
fibromyalgia
severe pain lasting longer than 6 mos and associated with impaired memory or concentration
sore throat, tender cervical or axillary lymph nodes
muscle pain
multiple joint pain
new onset headaches
nonrestorative sleep
postexertional malaise
chronic fatigue syndrome
Agitation and restlessness are common manifestations of
depression
anxiety
substance abuse
agitation, hypertension, and tachycardia occurring during the first 2 days after hospital admission
Alcohol withdrawal
Seizures may soon follow with delusions and delirium occurring during the first 3–5 days.
hallucinosis usually have a clear sensorium
Alcoholic hallucinosis (this is a distinguishing factor setting it apart from delirium)
Confusion, disorientation, and autonomic hyperactivity are hallmarks
delirium tremens (can be fatal)
Wernicke encephalopathy is not an alcohol withdrawal syndrome but is caused by
thiamine deficiency
Alcohol abuse is the most common cause of ___ deficeincy
Thiamine
Wernicke encephalopathy may occur when a patient, who is thiamine deficient, receives
intravenous glucose
Symptoms include the triad of confusion, disorders of ocular movement, and ataxia. The confusion commonly manifests as disorientation and indifference.
Wernicke encephalopathy
presents with memory problems and resulting confabulation
Korsakoff syndrome is the chronic form of Wernicke encephalopathy.
Adrenergic overactivity (hypertension, tachycardia, fever) is always present unless masked by medications.
delirium tremens
Alzheimer Disease most commonly occurs after the age of
65
Memory loss, behavioral or personality change, functional impairments, and social withdrawal
common early symptoms of AD.
most-evaluated instrument for diagnostic cognitive impairment
MMSE (mini mental status exam)
fluent aphasia, paraphasia, and word substitutions
language disturbances associated with AD
Highly educated patients are more likely or less likely to receive an early diagnosis for AD
less likely
3 tests for dementia
MMSE (mini mental status exam)
Mini-Cog
MoCA
IQCODE
which mental screening exam includes 3-item recall and clock drawing
mini-cog
which mental screening exam was Initially developed and validated as a screening test for MCI (mild cognitive impairment)
MoCA
which mental screening exam is a Short form is a 16-item questionnaire.
IQCODE
Considered the clinical gold standard for diagnosing dementia
Neuropsychiatric testing
Reasons to explore for reversible dementia
CNS infections
Hypothyroidism
Vitamin B12 deficiency
CNS masses
Neoplasms
Subdural hematomas
Normal-pressure hydrocephalus
Medications
tests for dementia
CBC
Thyroid-stimulating hormone (TSH)
Basic metabolic panel and liver biochemical tests
Vitamin B12 level
Tests to exclude neurosyphilis
Consider neuroimaging (MRI or CT)
Imaging is not required in most patients with dementia.
In practice, most patients will undergo imaging both to assess for diagnoses other than AD and to detect brain atrophy that may support the diagnosis of AD.
manifests as inattention and confusion
Delirium
Several conditions are more likely to cause delirium than others.
Severe illness
Drug toxicity
Fluid and electrolyte disturbances (hyponatremia and azotemia)
Infections
Hypothermia or hyperthermia
Delirium is very common in
sick, hospitalized patients over the age of 65
The prognosis of delirium is
poor
patients who experienced delirium had a higher risk of death, institutionalization, and dementia during follow-up.
the best-validated and most widely used tool for diagnosing delirium.
The Confusion Assessment Method (CAM)
typically seen in a patient with Parkinson disease who has dementia. In patients without a previous diagnosis of Parkinson disease, motor symptoms similar to those seen in Parkinson disease are often present.
Dementia with Lewy Bodies (DLB)
screening tool for Validated for use in older adults to assist in depression diagnosis
PHQ-9 (Personal Health Questionaire):
what type of dementia - Visual hallucinations are common
Dementia with Lewy Bodies (DLB)
Mild extrapyramidal motor symptoms (rigidity and bradykinesis) are often seen early in this type of dementia
Dementia with Lewy Bodies (DLB)
Repeated falls
Syncope
Transient loss of consciousness
Neuroleptic sensitivity
Systematized delusions and hallucinations
Dementia with Lewy Bodies (DLB)
what does SOAP note include
Chief Complaint (subjective) History of Present Illness (subjective) Family/medical/surgical histories (subjective) Review of systems (subjective) Physical exam (objective) Assessment Plan
most likely diagnosis based on prevalence, demographics, risk factors, signs & symptoms
Leading hypothesis
Hypothesis generating starts with
patient’s demographics
most significant factor of pt demographics
Age
problem specific framework for Frequently used for chest pain
anatomic
problem specific framework Used for problems with very broad differentials such as fatigue
Organ based /system based
PQRST
P(provocative, palliative) What brings it on, what makes it better
Quality - what does it feel like
Region/radiate where is it at and where does it radiate
Severity and setting - how bad is it? What were you doing at the time
Temporal - when did it start, how long does it last, have you had it before
what framework?
What could be happening pathologically(what diseases could) to make this symptom happen
organic
VINDICATE
Vascular, Infection Neoplastic Degenerative, Idiopathic/Inflammatory Congenital Autoimmune, Traumatic Endocrine
MEDICINE
Metabolic/Medication Endocrine Degenerative, Infection/Ischemia/Infarction Congenital Neoplastic, Electrical( Neuro/Psych)
VITAMINCDE
Vascular Infection/Ischemic/Infarction Trauma/Toxin Autoimmune Metabolic/Medications Iatrogenic/Idiopathic, Neoplastic Congenital Degenerative Electrical (Neuro/psych)
What is the order problems should be listed in a problem list
begin with the acute problems, followed by chronic active problems, ending with inactive problems (past medical history)
Organic (chronic) causes of fatigue
sleep apnea, medications, HF, cancer, EBV, hepatitis, fibromyalgia, chronic fatigue syndrome
Organic (acute) causes of fatigue
infection, drugs/alcohol, anemia, hypothyroidism, hyperthyroidism
fatigue presentation in children
Withdrawn from social and recreational activities → mood disturbances
fatigue presentation in adolescents
Withdrawn from social/recreational activities → mood disturbances
Decreased academic performance and decreased productivity
Recreational drug and alcohol use, high caffeine intake
an older patient complaining of memory loss. Common complaints are difficulty remembering names and appointments or solving complex problems
mild cognitive impairment
people have memory loss and no other deficits
Single domain amnestic MCI
people have memory loss as well as other deficits
Multiple domain amnestic MCI
people have impairment in a single, non–memory-related, cognitive domain.
Single domain non-amnestic MCI
people have impairment in multiple, non–memory-related, cognitive domain.
Multiple domain non-amnestic MCI
may be abrupt or gradual. The patient usually has risk factors for, or has previously diagnosed, vascular disease. The patient may have gait disturbance during the neurologic exam.
Multi-infarct Dementia (Vascular Dementia, VaD)
the most common cause of dementia after AD.
Multi-infarct Dementia (Vascular Dementia, VaD)
Most common in patients with risk factors for vascular disease or an embolic stroke
Multi-infarct Dementia (Vascular Dementia, VaD)
Screening tool for Multi-infarct Dementia (Vascular Dementia, VaD)
DSM-5 criteria
Exaggeration of deep tendon reflexes
Extensor plantar response
Gait abnormalities (consider history of unsteadiness and frequent, unprovoked falls)
Pseudobulbar palsy (pathologic laughing, crying, grimacing; and weakness of the muscles associated with cranial nerves V, VII, IX, X, XI, and XII)
Focal neurologic signs
Multi-infarct Dementia (Vascular Dementia, VaD)
clinically useful test for determining whether ischemic disease is playing a role in a patient’s dementia.
Hachinski Ischemic Score
cc fever
why is it important to ask about recent head trauma?
recent head trauma esp at base of skull may provide entrance for infectious organisms
cc fever
why ask about recurrent ear infections
may have mastoiditis spreading to meninges
headache fever lethargy confusion vomiting stiff neck
meningitis
why is fever younger than 2 mos significant
neonates and young infants are less able to mount a febrile response so when they do it is significant
fevers in a neonate may also be an indication of an
underlying anatomical defect
URI and bacteremia is often the first indications of a structural abnormality of the urinary tract
genetic disorder that may present in the first weeks to 1 month of life with gram negative sepsis
galactosemia - rare genetic metabolic disorder (affects ability to metabolize the sugar (galactose) properly
all infants younger than 2 months with fever are considered to have ____ or ____ until proven otherwise
Sepsis or meningitis
in adults fevers from acute process usually resolves in
1-2 weeks
fevers that last > 3 weeks that exceed temp of 38.4 (101.1) and remain undiagnosed after 1 week of intensive diagnostic study are classified as
FUOS
fever in children with short duration, readily diagnosed and resolves within 1 week
short term fever
fever in children < 10 days that is not explained by findings on history or physical exam
fever without localizing signs
fever in children greater than 38.5 (101.2) that lasts longer than 2 weeks on more than 4 occasions
FUOs
Fever greater than 41.1C (106) are seen in
heat illness
CNS disease
infection
the higher the fever, the greater likelihood of
bacteremia
most common infection in girls younger than 2 years old who present with a high fever and in all infants younger than 90 days with a fever
UTI
fever
increased amount of vaginal discharge and bleeding after intercourse
PID
chills high fever urinary frequency and urgency perineal pain low back pain penile discharge
acute UTI in male
CC fever
joint pain
connective tissue disorder in adults and children older than 6.
osteomyelitis or septic arthritis
rash for hand foot mouth usually erupts on what day
3 days
rash for measles usually erupts on what day
4 days
Rash for roseola infantum usually erupts on what day
5 days
rash for scarlet fever usually erupts on what day
2 day
rash for varicella, rubella, erythema infectiosiosum usually erupts on what day
1
infections to r/o with history of travel outside the country
amebiasis malaria schistosomiasis typhoid fever hepatitis A or B Dengue
the most common vector borne disease worldwide and is a diff diagnosis for pt who live or have recently traveled to the tropics or subtropical areas of the US
Dengue
recent camping or exposure to wooded areas may indicate
exposure to ticks Q fever tularemia rocky mountain spotted fever giardia lyme disease
what overdose can cause fever
ASA
food poisoning fevers can occur up to ____ hours after ingestion of contaminated food
72
what plants can cause fever
plants containing the alkaloid atropine (deadly nightshade, jessamine, and thornapple)
cause dilated pupils, flushed skin and fever
bacterial infection transmitted by cats (changing kitty litter boxes. )
Cat-Scratch disease or toxoplasmosis (single node or regional adenopathy is the dominant clinical feature)
What is the etiologic agent of Cat Scratch disease
Gram neg bacillus
bacterial infection transmitted by dogs
brucellosis and leptospirosis
bacterial infection transmitted by rabbits
tularemia
bacterial infection transmitted by birds
ornithosis
histoplasmosis
psittacosis
bacterial infection transmitted by hamsters or cats
lymphocytic choriomeningitis
hyperthermia and change in LOC
classic heat stroke
causes of fever of unknown orgin in child
infectious disease (localized and systemic) collagen/inflammatory diseases neoplastic diseases drug fever factitious fever kawasaki disease inflammatory bowel disease immunodeficiency CNS dysfunction
CC fever
petechial eruptions on the hard and soft palate
mononucleosis
cc fever
splinter hemorrhages found in the nail beds and petechiae of the conjunctivae
endocarditis
cc fever
petechial skin rash
meningococcemia
rocky mountain spotted fever
anticoagulation treatment outside of therapeutic range
indicates a serious infection that requires immediate referral and hospitalization
inspecting the fontanel of an infant is best noted if the patient is in what position
sitting
cc fever
palpable anterior cervical lymph nodes
suspect viral or bacterial pharyngitis
cc fever
palpable preauricular or postauricular lymph nodes
suspect ear infection
cc fever
palpable submental and submandibular lymph nodes
suspect tooth abscess
cc fever
palpable posterior cervical lymph nodes
suspect mononucleosis