Test #1 Flashcards
Steps in an Action Potential
When one nerve cell is activated it sends information like a neurotransmitter down through the axon via a vesicle which protects it and keeps it all there which then brings it to the edge of the presynaptic neuron which goes pew and sends it into the synaptic gap and then the receptors are what takes in the neurotransmitter, reuptake when the presynaptic nerve RECYCLES the neurotransmitter that is existing in that presynaptic gap
a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter.
Presynaptic Neuron
a chemical substance that is released at the end of a nerve fiber by the arrival of a nerve impulse and, by diffusing across the synapse or junction, causes the transfer of the impulse to another nerve fiber, a muscle fiber, or some other structure.
Neuotransmitters
store various neurotransmitters that are released at the synapse.
Vesicles
cell’s gatekeeper. It’s the outer layer that surrounds a cell, letting substances in - or keeping them out.
Cell Membrane
a junction between two nerve cells, consisting of a minute gap across which impulses pass by diffusion of a neurotransmitter.
Synapse
Nerve cell on the receiving end of an electrical impulse from a neighboring cell
Post Synaptic Neuron
proteins that are on the surface of each cell. They act as little receivers (or ears) that listen to the messages of the chemical messenger molecules as they float in the intercellular fluid surrounding every cell.
Receptor Site
the process by which the presynaptic terminal of a neuron reabsorbs and recycles the molecules of neurotransmitter it has previously secreted in conveying an impulse to another neuron.
Reuptake
the space between neurons at a nerve synapse across which a nerve impulse is transmitted by a neurotransmitter
The gap between the presynaptic gap and the post synaptic nerve, its where the neurotransmitters go and then the receptors receive it
Synaptic Gap
o Responsible for communication and integration in the nervous system
Neuron
Input to the neuron
Dendrites
Output of the neuron
Designed to carry information
Branch to connect to go to different neurons
Axon
End; make the connection with the other neuron.
Axon Terminal
BODY -> DRUG
How the body moves or processes the drug
How your body effects the drug
Pharmacokinetics
ADME of Pharmacokinetics
Absorption
Distribution
Metabolism
Excretion
Max concentration when drug in blood stream
Peak Concentration
When med in blood stream is at its lowest, wait to take next dose of meds
Trough Levels
Amount of time required to reach a stable concentration level in blood stream, the amount entering your body is equal to the amount leaving your body
Half-Life
Amount of time required for drug to be stable in blood stream amount entering is equal to amount exiting
Steady State
Concentration in liquid portion of the blood
Therapeutic index: window having meds concentrated rather than toxic
Plasma Levels
Minimum concentration much be reached for effectiveness and not exceeded
Therapeutic Window
DRUG -> BODY
How the drug affects the body
“Start low and go slow”
Work your way up to see what’s the best dosage
too much could be toxic
Pharmacodynamics
Something that “mimics” an already occurring neurotransmitter in the body, chemical process already occurring in the body
Agonist
