Test 1

Question 0

Tissue factor that is a cofactor

Answer 0

Factor VIII

Question 1

Normal fibrin split product value

Answer 1

<10ug/dL

Question 2

What initiates the coagulation cascade in vivo?

Answer 2

Tissue factor

Question 3

In vitro, which zymogen is activated after collagen is exposed to blood?

Answer 3

Factor XII, Hageman Factor, Antihemophilic factpr D

Question 4

Insufficient vWF most likely causes?

Answer 4

Insufficient clot adhesion

Question 5

If a drug prolongs the TT and PT tests, which pathway is not affected?

Answer 5

Intrinsic pathway

Question 6

First step of hemostasis process when an arterial vessel is damaged?

Answer 6

Vascular constriction

Question 7

Natural anticoagulation affect of ADPase?

Answer 7

Limits ability to recruit more platelets

Question 8

vWF is produced by?

Answer 8

Endothelial cells

Question 9

Which of the following platelet surface receptors initially binds von Willebrand’s Factor to enhance platelet adhesion?

Answer 9

GP1b

Question 10

Which of the following autologous anticoagulants involved in coagulation Termination is inactivated by Factor lla as part of a negative feedback?

Answer 10

Protein C

Question 11

Which anticlotting substance works on Factors 5 and 8?

Answer 11

Protein C

Question 12

4 serine processes inhibited by ATIII?

Answer 12

Activated Stuart factor
Antihemophilic factor B
Antihemophilic factor C
Antihemophilic factor D

Question 13

Feasible therapy for ATIII deficiency

Answer 13

Transfusion of FFP
Administration of Atryn
Administration of Thrombate

Question 14

What percent of patients with current DVT secondary to HIT Type II develop further thrombosis?

Answer 14

50%

Question 15

DOC for HIT Type II

Answer 15

Argatroban

Question 16

Which method of determining Protamine dose is most affected by Heparins half life?

Answer 16

Fixed dose

Question 17

Advantage of using protamine titration method

Answer 17

Absence of heparin rebound

Question 18

Which class of antibody mediates true Protamine anaphylactic reactions?

Answer 18

IgE

Question 19

What is a high CVP on bypass associated with?

Answer 19

Impaired venous drainage

Question 20

Ideal rate of UO on bypass?

Answer 20

0.5-1 ml/kg/hr

Question 21

What causes an acute hemolytic reaction?

Answer 21

ABO incompatibility

Question 22

Why is too much citrate dangerous?

Answer 22

It depletes K and Mg stores

Question 23

RAP can remove how much prime?

Answer 23

200-600mL

Question 24

Deep hypothermic circulatory arrest (DHCA) would be utilized if your patient was cooled to which of the following temperatures (as given in the lecture

Answer 24

23C

Question 25

Profound hypothermic circulatory arrest (PHCA) would be utilized if your patient was cooled to which of the following temperatures (as given in the lecture slides)?

Answer 25

16C

Question 26

At what temperature will the brain lose autoregulation of blood flow no matter what hypothermic acid-base strategy is being used?

Answer 26

20C

Question 27

Which of the following are you practicing if the patient’s temperature is 28o C and you keep the temperature corrected pCO2 at 28 mmHg?

Answer 27

Alpha stat

Question 28

Min flow for Terumo RX25 oxygenator?

Answer 28

0.5LPM

Question 29

What is the maximum flow for the cardiotomy filter in the RX25 Oxygenator with hardshell reservoir that should NOT be exceeded?_______________________ (in Liters per minute only)

Answer 29

5LPM

Question 30

What is the maximum gas flow rate that should not be exceeded for the Terumo RX25 oxygenator?___________________ (in liters per minute)

Answer 30

20LPM

Question 31

What is the maximum recommended volume that should not be exceeded with the Terumo RX25 oxygenator with an intergral hardshell reservoir?

Answer 31

4L