Test 1 Flashcards
Over ventilation can lead to what acid-base imbalance?
Respiratory Alkalosis
Tx acute GI bleed dt portal HTN
octreotide
MC primary intracranial tumor
meninigioma
Tx RMSF
Doxycyline
MCC Encephalitis and Tx
MCC is HSV
Tx Acyclovir IV
Gold standard to dx HSV encephalitis
CSF PCR for HSV
TV CMV encephalitis in HIV pts
Ganciclovir
TX for tertiary syphilis
PCN IV/IM x10-14 days
MC PEDS brain tumor
medulloblastoma
most devastating PEDS malignancy
brainstem glioma/DIPG
MC malignant brain tumor
astrocytoma
- includes GBM
brain tumor with “dura tail”
meningioma
MC pituitary adenoma
and sxs you could expect
prolactinoma
gallactorhea, Gynecomastia, amenorrhea, infertilitly
unilat hearing loss, tinnitus, episodic vertigo
suspect what CA
acoustic neuroma
cutaneous neurofibromas all over the body what is the dx
Type 1 Neurofibromatosis
maculopapular rash involiving palms and soles that spreads centripetally up the trunk
RMSF
Stage 1 HTN is categorized as
SPB 140-159 or DBP 90-99
Stage 2 HTN is categorized as
SBP >160 or DBP >100
Acute onset CHF sxs in young person or person w/o CAD risks suggests
myocarditis
GOLD STANDARD to confirm myocarditis
endomyocardial biopsy
MC cardiomyopathy and sxs to expect
Dilated cardiomyopathy
SXS: progressive CHF sxs, LHF sxs
DOE, SOB, PND, Orthopnea, JVD, Edema
GOLD STANDARD to dx dilated cardiomyopathy
ECHO
Beck’s TRIAD
Dx
Tx
HoTN, muffled heart sounds, JVD
= Cardiac Tamponade
emergenct cardiocentesis
Rheumatic fever MC affects what heart valve?
Mitral
cause of rheumatic fever
immune mediated disease triggered by GABHS
MC organism in endocarditis
Strep viridans
MI EKG changes in II, III, or aVF means occlusion in___ infarct location is _____
changes in inferior leads
RCA or descending
Inferior infarct
MI EKG changes in I, aVL, V5, V6 means occlusion in____ infarct location is_____
changes in lateral leads
left circumflex
Lateral infarct
MI EKG changes in precordials, V1-V6 means occlusion in____ infarct location is____
changes in precordial leads
LAD
Anterior infarct
ST depression with (-) biomarkers
DX
Unstable angina
EKG with diffuse T wave peaking
hyperkalemia
EKG abnl not meeting MI criteria
(+) biomarkers
NSTEMI
tracheal deviation, hyper-resonance, HoTN
tension pneumothorax
immed decompression
18g to 2-3rd ICS followed tube thoracostomy
negative bifringent cystals
gout
Heparin- monitor which blood test
aPTT
Warfarin (Coumadin)- monitor which blood test
PT/INR
ASA antiplatelet effects lasts how long
8-10days, irreversible
Hemophilia A is a def in which factor
8
Hemophilia A will have a prolonged____ (blood test)
PTT
Tx Hemophilia A
Factor 8 concentrate
DDAVP can be used for minor bleeds
Hemophilia B is a def in which factor
9
“Christmas disease”
Hemophilia B
Tx Hemophilia B
Factor 9 concentrate
“Hemophilia C” is def in what
Factor 11
minor bleeding into soft tissue, hemarthrosis, arthropathy in Ashkenazi Jew
Factor 11 def “Hemophilia C”
Tx “hemophilia C”
FFP
MC inherited bleeding disorder
von Willebrand Disease (vWD)
sxs of vonWillebrand
platelet type bleeding: bruising, petechiae, gingival bleed, epistaxis
Tx vonWillebrand
DDAVP or vWF concentrate in major bleed or in Type 3
Dx TTP
decreased activity ADAMST13
Tx TTP
IMMED Plasma exchange
platelets contraindicated
Rheumatoid arthritis assoc with what gene
HLA-DR4
Pt with hx installation has dry cough. CXR shoes linear opacities of various sizes in bilat bases. Dx
Asbestosis
Pt with hx rock mining has dry cough. CXR hilar node calcification. Dx
eggshell pattern
Silicosis
sxs of venous congestion go with which sided HF
Right
MC cardiomyopathy
dilated
A thickened but nondilated LV is dx of
hypertrophic cardiomyopathy
Treatment of cardiogenic shock
ABCs
fluid challenge for HoTN first then dobutamine
PCI cath with possible intra-aortic balloon pump
w/o for acute onset CHF in young patient or pt w/o CAD risks
cardiac MRI with Gadolinium first
endomyocardial bx is gold standard to dx myocarditis
sxs of rheumatic fever
J: joints- usually 1st sign <3: carditis N: nodules sub q E: erythema marginatum S: Sydenham chorea
tx for rheumatic fever
bed rest, symptomatic ASA use
PCN IM and then q month
empiric tx endocarditis
vanco + gent +/- ceftriaxone
“rice water” stools
dx
tx
Cholera
Fluids and Tetracycline
watery diarrhea that progresses to mucus and blood
tenesmus, fever
stool cultures show increased neutrophils
Shigellosis
TOC fluoroquinolone
CD4 <200
prophylaxis Pjiroveci
Bactrim
dx polycythemia vera
pruritus after a warm shower
high HCT
JAK2 mutation
Philadelphia chromosome
CML
Auer rods
AML
MC leukemia in children
ALL
cells expressing TdT (terminal deoxynucleotidyl transferase)
ALL
sudan black esterase
AML
isolated lymphocytosis and smudge cells on peripheral smear
CLL
chronic lymphocytic leukemia
reed Sternberg cells
Hodgkin Lymphoma
65yo AAM complaining of bone pain in hip, increased thirst, and constipation. Xray shows fx of femoral neck labs show hypercalcemia suspicion for- dx-
Multiple Myeloma
RBC morphology with Rouleaux formation
Bence Jones proteins in urine
xray evidence of “punched out” lytic lesions
Bence Jones proteins in urine
multiple myeloma
Sxs of Multiple myeloma
bone pain (commonly back, hips, ribs) anemia sxs infection with encapsulated orga (Spneumo) hypercalcemia hyperviscosity syndrome spinal cord compression
TX PID outpt regimen
Ceftriaxone
Doxy
Flagyl
Tx for GC chlamydia
which abx specific for each?
general tx
Ceftriaxone 250mg IM (spec gonorrhea)
Azithromycin 1g PO (covers chlamydia)
painful necrotizing genital ulcer with inguinal LAD
dx
tx
Chancroid (Haemophilus ducreyia) no specific labs gram - rods in school of fish appearance if sure of dx can just do 1 or 3: azithromycin, ceftriaxone, cipro
MC sign of bladder CA
painless hematuria
Tx outpt pyelonephritis
Fluoroquinolone= Cipro
Bactrim
tender prostate “boggy”
dysuria, fever
acute bacterial prostatitis
cipro x21d
Labs for Diabetes Insipidus
serum osmolarity high, urine low
normal to hypernatremia
central responds to vasopressin test
nephrogenic wont respond to vasopressin
whooping cough or adult with cough x2wks
dx
tx
Pertussis (Bordetella pertussis)
nasopharyngeal culture, ~PCR
Azithromycin, erythromycin, etc x7d
chvostek sign
facial muscle contractions after tapping facial nerve in front of ear
sign of hypocalcemia
consider hypoparathyroid
Trousseau phenomenon
carpal spasms after application of BP cuff inflation
sign of hypocalcemia
A1c of 6.0 = glucose of
q1% is a rise of what in blood sugar
125 nl
1%=30
10pm glucose= 110
3am glucose = 110
7am glucose= 150
Dawn phenomenon
increase pm insulin
10pm glucose= 110
3am glucose = 50
7am glucose= 200
Somogyi effect
decrease pm insulin or more food at bedtime
when do you lower BP during stroke?
If >185/110