test 1 Flashcards
4 skin random facts
- largest single organ in the body
- 1/3 of the circulating blood in the body is in the skin
- 20% available protein is used by skin for epidermal replacement
- contains sensory receptors
3 layers of skin and sub layers
1. epidermis: stratums deep -> superficial: germnativum, sinosum, granulosum, ludicum, corneum 2. dermis- str paplare,str reticulare 3. hypodermis
A & P of the edpidermis (5)
- multilayers structure which replaces itself by cell division
- deepest layer is basal cell
- epidermal cells are referred to as keratinocytes
- keratinization is the cells ascending towards the surface
- the skin surface is dead
a&p edpidermis- cell types (3)
keratinocytes- 1. most prevalent 2. considered dead but because of high lipid content form impermeable barrier and keeps water in melanocytes 1. basal cell and give color langerhans cell 1. immune response
dermis (4) 2 layers- composed of 3 things contains... principle purpose
- two layers- papillary layer and reticular layer
- dense irregular, mesodermally derived connective tissue composed of collagen elastin and GCGs
- contains extensive vasculature, nerves, sweat and sebaceous glands, smooth muscles and fibroblasts
- principle mechanical skin barrier
3 types of dermal cells and what they do
- macrophage- phagocytosis
- mast cells- phagocytosis
- release chemicals to attract other cells to area (serotonin) - fibroblasts- lay down new tissues
skin functions (4)
- prevention of loss of essential fluids (stratum corneum)
- thermoregulation because of specialized structures of dermis
- calcium homeostasis and synthesis of vit D
- huge sensory organ
hypodermis (3)
what its made of
purposes
what happens if injured or destroyed
- subcutaneous tissue that is comprised of connective (fascia) and fat tissue
- provides:
insulation, shock absorption, energy storage, keratinocytes - when epidermis is destroyed, lose nourishement** because major blood vessels of skin
wound healing- inflammation days 3-7 (4)
- hemostasis = control of bleeding, vasoconstriction -> dilation
- mast cells release seretonin
- chemotaxis to attract chemicals
- increased platelet activity (to cause clotting) which release of growth factor
3 phases of wound healing and time table
-these are not discrete phases, some overlap
- inflammation- immediate up to 3-7 days
- proliferation= fibroplasia- day 3-21. when wound is closed => maturation
- remodeling = maturation= day 21-2 years
wound healing- proliferation phase 4-24 days (5)
- fibroplasia- laying down fibrin and elastin, profuse blood flow
- granulation- laying down new granulated tissue
- angiogenesis- creating new BV= reestablishing blood flow into the wound
- re-epithelization- migration of epidermal cells on surface of wound
- wound contraction- getting smaller because myofibroblast start to pull edges of wound in
maturation phase/ remodeling (2)
- collagen orientation and lysis
2. increase in tensile strength
per secundam intentionem (3)
- large or infected
- wound contraction and development of granulation tissue from depth and margins of wound
- slow process resulting in scars
per tertiary intentionem (2)
- skin is minimally healed with restored anatomical but not functional continuity
- eg- skin grafts or transplants
4 cardinal signs of inflammation (+1)
- calor (heat)
- rubor (redness)
- dolor (pain)
- tumor (swelling)
- loss of function
per primam intentionem (first intention)(3)
- uncomplicated healing of injury when continuity of tissue is reestablished w/o infection
- small, smooth, approximated wounds
- surgical incision => usually scarless
oscillometry (non-invasive vascular test) (2)
- place cuff around artery where you are concerned with pathology
- inflate cuff for partial occlusion and sensor in cuff can read pulse => get visual representation of strength of pulse
transcutaneous partial O2 pressures (TcPO2) (non-invasive vascular test)
basic (1)
normal and not-normal values (3)
not valid if…(2)
- measures partial pressure of O2 to skin with special machine with sensors on skin (adjacent to wound)
- > 40mmHg = normal
- 30-40mmHg = impaired but can heal
- <30 mm Hg = severely impaired healing- prognosis not as good
- not valid if severe infection or edema
debridement indications (4)
- removal of dead, devitalized, damaged tissue or foreign materials and microorganizms
- helps with infection management (these microorganisms or foreign tissue are breeding grounds for bacteria)
- allow for fibroplasia (proliferation phase of healing can only happen if no dead tissue)
- helps evaluate true wound depth
segmental systolic pressures (non-invasive vascular test (2)
- measuring systolic pressure down leg (thigh, calf, ankle)
2. should decrease as you go down but a change of >20mmHg indicates pathology**
contraindications for sharp debridement (6)
- arterial insufficiency (low ABI)
- blood thinners or asprin
- clotting disorders
- gangrenous tissue (wet gangrene needs surgery,, dry falls off on its own)
- stable heel ulcer
- unidentifiable structures
guidelines for sharp debridement (13)
- all items accessible and sterile
- hand washing and gloving
- optimal positioning for pt and self
- good lighting
- appropriate disposal container
- plan for controlling bleeding
- partial wound cleansing
- wound evaluation
- repeat hand washing and gloving
- conservative approach
- avoid excessive pain and bleeding
- pt and clinician fatigue => multiple short sessions (3-20m)
- integration with other forms of debridement
wound scrubbing (mechanical debridement) (3)
- gentle
- from center to periphery
- instrument called curette which has like a nail file
sharp debridement objective time instruments who can do it? pain management procedure
- objective: only gets rid of dead tissue that is ready to be removed - based on how adherent or painful
- time: only last about 15 min
- instruments: use forceps, scapels
- PT/OT, podiatrists, nurses can all do it
- can be painful so pre-medicate patient
- procedure: cross hatch (score thru tissue) then can remove little squares of necrotic tissue with tweezers or enzyme