Test 1 Flashcards
What are the components of the first line of defense?
Unbroken skin, secretions such as mucus, sebum, lactic acid in sweat, ear wax, and stomach fluids. IgA, acidity and alkalinity, tears, cilia in lungs, and saliva.
What is the function of the immune system?
To recognize self from non-self and to defend the body from non-self.
What are the components of the 2nd line of defense?
AKA natural immunity
Composed of cellular and humoral defense.
Cellular - Mast cells, neutrophils, macrophages
Humoral - Lysozymes, intereferon, complement
What are the components of the 3rd line of defense?
AKA adaptive immunity
Allows the body to recognize, remember, and respond to a specific stimulus, an antigen.
What are the consequences of the immune system?
Allergies, rejected transplant organ, autoimmune disorder
What is Innate immunity?
Natural or inborn resistance to infection after microorganisms have penetrated first line of defense.
What is acquired immunity?
Augmentation of the body defense mechanisms in response to a specific stimulus, which can cause the elimination of microorganism and recovery from disease. This response usually leaves the host with a specific memory (acquired resistance) which enables the body to respond effectively if reinfection with the same microorganisms occurs. Organized around T and B lymphs.
What are the types of acquired immunity??
Cellular and Humoral
What is artificial passive immunity?
Infusion of serum or plasma. Provides immediate protection but only temporary.
What is artificial active immunity?
Vaccination, which may consist of living suspensions, killed cells, or viruses, and extracted bacterial products.
What is active immunity?
The form of immunity produced by the body in response to stimulation by a disease-causing organism.
What is immediate hypersensitivity?
Process of the release of potent chemical mediators from sensitized mast cells mediated by IgE.
What is cell-mediated immunity?
Moderated by a link between T lymphs and phagocytic cells. A immunity that has lymphs which helps with immunologic specificity.
What are five factors that are associated with immunologic disease?
Age Nutrition Proteins, carbs, and lipids Vitamins and Minerals Brain
What is the MHC?
Major histocompatability complex.
A genetic region in humans and other mammals responsible for signaling between lymphs and antigen bearing cells. Also a major determinant of transplant compatibility.
