test 1 Flashcards
What is the Krogh principle?
For a large number of problems the will be some animal of choice, or a few animals, on which it can be most conveniently studied
What was Knut Schmidt-Nielsen known for?
shifted physiology from human medicine to biology more broadly
What was George Bartholomew known for?
His integrative view of biology
What was Per Scholander known for?
Plants and animals in extreme environments
What two questions does physiology try to answer?
- what is the mechanism by which a function is accomplished?
- how did that mechanism come to be?
What is the most abundant phylum?
Arthropoda
When did bats evolve?
Approximately 60 million years ago
What did we learn about exercise physiology in class?
Typically, animals use carbs at high intensity (90% carbs) but it runs out quickly. As you exhaust your carb stores, intensity lowers and the animals switches to mostly lipids (40% carbs).
How do flying animals use their energy stores?
They cannot reduce their metabolic rate, so they use mostly fatty acids (lipids).
Describe the digestive physiology of flying animals
Bats and bird digestive tracts have lower surface to volume ratios. They allow some substances to pass between the cells.
Is echolocation in whales and bats homologous or analogous?
analogous
Where are action potentials initiated?
axon hillock
What are the 4 glial cells and their functions?
oligodendrocytes - insulation and support
astrocytes - connect capillary and neuron
microglial cells - act as phagocytes and aid immune function
Schwann cells - myelination
cells maintain high intracellular [___] and low [___] and [___], compared to extracellular matrix
high K+ and low Na+ and Cl-
What is the Goldman equation?
E = 58 log (Pk [K+]o + PNa [Na+]o) / (Pk [K+]i + PNa [Na+]i)
Do action potentials degrade over space?
No.
Describe the initial resting phase
K permeability»_space; Na permeability. Inside charge is -65mV
Describe the rising phase
Na voltage-gated channels open, Na permeability»_space; K permeability, and inside is positive 40mV
Describe the falling phase
Na channels are inactivated, voltage-gates K channels open, K permeability»_space; Na permeability
Describe the recovery phase
voltage gates K channels remain open for a few ms, resulting in hyperpolarization (undershoot), K permeability > Na permeability
Describe the evolution of voltage-gated channels
Voltage-gated Na+ channels, K+ channels, and Ca+ channels most likely evolved from bacterial K+ channels
Bidirectional propagation is prevented by ________
refractory period
What factors affect the speed of transduction?
Neuron diameter, myelination, temperature
All else being equal, larger axon diameters result in _______ action potentials
faster