Test 1 Flashcards

1
Q

What is pharmacology

A

Study of drugs that alter functions of living organisms

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2
Q

What is drug therapy

A

Use of drugs to prevent, or treat sign symptoms and disease process

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3
Q

Metabolism - cytochrome 450(enzyme)

A

Impacts the ability to metabolize drugs

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4
Q

Inactive metabolites

A

Have no biological effect

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5
Q

Active metabolites

A

Produces some sort of biological effect

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6
Q

Prodrugs

A

Become active when they are metabolized

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7
Q

What is bioavailability

A

It is how much medication is in the blood stream

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8
Q

Excretion

A

Elimination of the drug form the body

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9
Q

Agonists

A

Drugs that interact with a receptor to stimulate a response

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10
Q

Antagonists

A

Attach to a receptor but does not stimulate a response

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11
Q

Pharmacokinetics

A

How to the medications move through the body via their administration

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12
Q

Pharmacodynamics

A

How target cells in the body respond to the medication

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13
Q

Additive

A

When drugs interact their combined effects increase the therapeutic effect

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14
Q

Synergism

A

When drugs interact and the drugs work together that amplifies their combined therapeutic effects

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15
Q

Interference

A

When drugs interacts and one stops another

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16
Q

Displacement

A

When the drugs interact they compete to bind to the specific site so the first drug that was bound to the receptor will get “kicked out” and released into the bloodstream, therefore increasing the effects while the second drug binds to the now available receptor and continues to increase the effects of the drug

17
Q

What is distribution dependent on

A

Perfusion and protein

18
Q

Serum drug level

A

A lab measurement of the amount of drug within the blood

19
Q

Inactivation

A

The drug stops certain activities in the cell

20
Q

Activation

A

The drug can start
/ speed up activities in the cell

21
Q

Alteration

A

The drug can change how some things work inside the cell

22
Q

Transduction of pain

A

Pain begins when there is a harmful stimulus and activates nerve endings called nocioreceptors that are located throughout the body

23
Q

Transmission of pain

A

Propagation of signal: these electric signals along fiber that are part of the peripheral nervous system neurotransmitters release signals that continue along the nerve pathway

24
Q

Somatic pain

A

Localized in skin, bone, soft tissue from stimulation of nocioceptors

25
Q

Visceral pain

A

Pain resulting from stimulation of nociceptors in the abdominal and thoracic regions

26
Q

Neuropathic pain

A

Caused by lesions or changes to the peripheral pain nerves