Test #1 Flashcards
Name the small openings in the aortic arch, just past the aortic valve.
Orifices of coronary arteries
Describe the muscular attachments of the heart.
There are none; it hangs from the aorta
Name the 3 sizes of cardiac cells and their primary function
Small: weakly contractile, auto rhythmic, slow AP conduction
Intermediate: strongly contractile, make up bulk of heart
Large: weakly contractile, specialized for fast impulse conduction
What is the average and mean pressures of the pulmonary and systemic circuits and heart chambers?
R. Atrium: 2 R. Ventricle: 25 Pulmonary circuit: 25/8 (mean:14) L. Atrium: 5 R. Ventricle: 120 Systemic arteries: 120/80 (mean: 93) Veins: 10
Define cor pulmonare.
Enlargement of right side of heart..
What are the 3 variable that affect stroke volume?
EDV (end diastolic volume or preload)
TPR (total peripheral resistance or after load)
Contractility (frank starlings law)
Compare the amount of blood/oxygen supply going to the heart during rest vs. heavy exercise.
Unchanged: cardiac supply remains consistent at about 4-5%
Musculoskeletal goes from 15-20% to 80-85%
Explain the electrical conduction system in a healthy heart.
SA (sinoatrial) node, AV (atrioventricular) node, Bundle of His (L & R bundle branches), purkinje fiber system
What ion causes an action potential (depolarization) to occur in auto rhythmic cardiac cells?
Ca+2 (calcium ion)
What are the 3 phases of an action potential for SA & AV cell?
Phase 4: spontaneous depolarization
Phase 0: full depolarization
Phase 3: repolarization
Name the 4 phases of an action potental in cardiac CONTRACTILE cells.
Phase 4: table resting potential Phase 0: full depolarization Phase 1: initial repolarization Phase 2: calcium plateau Phase 3: repolarization
During cardioversion, which part of the heart cycle does the monitor sync and shock?
R wave - this avoids the “vulnerable period” of the cycle (middle to end of t wave)
How does the parasympathetic system slow heart rate?
increases the cells permeability to K+ (potassium ion) which allows K+ to leak and the cell becomes hyperpolarized (more negative) reducing the likelihood of an AP
How does the sympathetic system affect heart rate?
Decrease K+ leaving the cell, increases slow intake of Ca++ and Na+ to cause faster cell depolarization
Describe the mechanism of a sodium channel blocker.
Blocks sodium channels responsible for (phase 0) depolarization. This decreases the slope and amplitude of depolarization.
Describe the mechanism of a Potassium channel blocker.
Blocks the potassium channels responsible for (phase 3) repolarization. This increases AP duration and refractory period.
Describe the mechanism of a Calcium channel blocker.
Block calcium channels on vascular smooth muscle, cardiac myocytes, and cardiac nodal tissue. This causes vasodilation, decreased cardiac force, decreased heart rate, and decreased conduction velocity.
Define the mechanism of Beta-blockers
Blocks action of nor-epi at beta 1 receptors in the heart
Define Coranary Heart Disease
Reduced blood flow to coronary arteries causes hypoxia, impaired function, and leads to infarction.
What is the diaphragm of the stethoscope best for hearing?
Heart, respiratory, bowel (higher pitched sounds)