test 1 Flashcards
chemical drug name
only one name for each med.
name comes from ingredients
father of modern pharm
John Jacob Abel
therapeutics
focuses on disease prevention as well as treatment and pain
pharmotherapy
application of drugs for treating and alleviating pain
biosimilar drugs
close but not equivalent to the name brand
generic drug names
only one drug name
less complicated and easier to remember
bioavailability
amount of drug that enters systemic circulation and reaches the target organ or tissue
-dependent on dose, form (how body absorbs) or metabolsim
-fastest way is thru IV
mm to cm
1cm is equal to 10 mm
cm to m
1 meter is equal to 100 cm
m to km
1 km is equal to 1000 meters
mcg to mg
1mg is equal to 1000 mcg
mg to g
1 g is equal to 1000 mg
kg to g
1 kg is equal to 100 g
mL to L
1 L is 1000 mL
dL to L
1 L is 10 dL
lbs to kg
1 kg is 2.2 lbs
tsp to mL
5 mL Is 1 tsp
Tbsp to mL
15 mL is 1 Tbsp
oz to mL
30 mL is 1 oz
c to mL
240 mL is 1 c
milliequivilant (mEq)
measures the ability of a substance to mix w another substance
when you convert small to large you
move the decimal to the left
converting large to small
move decimal to right
black box warnings
dangerous possible effects
4 phase therapeutic
preclinical investigation
clinical investigation
review of new drug app
post market surveillance
withdrawl
physical discomfort felt by individual when substance isn’t used
schedule 1 drug
highest potential for abuse
schedule V drug
least potential for abuse
teratogenic
has potential to effect un born child
X- unsafe
A- safest
pharmacokinetics
how the body handles meds
absorption, distribution, metabolism, excretion
absorption
movement from site of administration , across body to circulation
distribution
transport of drug from circulation to body tissue. effected by blood flow
metabolism
chemically converts drugs so it can be easily removed from body
first pass effect
drug absorbed- goes to liver- metabolizes- leaves liver- distributed to general circulation
primary site of excretion
kidneys
enterohepatic recirculation
some drugs excreted in bile. recirculates. prolongs activity- could lead to toxicity
drug plasma concent
concent of med at target tissue
length of time needed to decrease drug concent by one half
half life.
the greater half life, longer it takes to excrete
loading dose
higher amount of drug given, quickly produces therapeutic effect
pharmacodynamics
how a med changes the body
therapeutic index
measure of drug safety
*Higher value, safer drug
potency
dose needed to produce effect
-higher potency, lower therapeutic
efficacy
magnitude of maximal response that can be produced by particular drug
drug attaches to receptor:
alpha or beta
agonist
limit receptor
parcial agonist
weaker, less effective response
antagonist
occupy receptor, doesn’t activate. no response
6 rights
Right patient
Right drug
Right dose
Right route
Right time
Right documentation
3 checks
Check 1- check time of admin, name and dose against MAR
Check 2- checking meds w MAR after attained and before going to patient room
Check 3- check MAR 3 times ensuring right patient is about to receive right med