Terms From Reading Flashcards

1
Q

What is Translational Research?

A

Bridges basic research and clinical research and clinical research by applying scientific discoveries to the improvement of clinical outcomes

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2
Q

What is research?

A

The process of systematically and carefully investigating a topic in order to discover new insights about the world.

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3
Q

What is Exposure?

A

Personal characteristic, behavior, environmental encounter, or intervention that might change the likelihood of developing a health condition.

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4
Q

What is Risk Factor?

A

Exposure that increases an individual’s likelihood of experiencing a particular disease or outcome.

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5
Q

What is Protective Factor?

A

An exposure that reduces an individual’s likelihood of experiencing a disease or outcome

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6
Q

What is Nonmodifiable Risk Factor?

A

Risk factor for a disease that cannot be changed through health interventions (age)

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7
Q

What is Modifiable Risk Factor?

A

Risk factor for a disease that can be avoided or mitigated

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8
Q

What is Primary Prevention?

A

Health behaviors and other protective actions that help keep an adverse health event fro occurring in people who do not already have the condition (exercise, nutritional diet)

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9
Q

What is Secondary Prevention?

A

Detection of health problems in asymptomatic individuals at an early age (cancer screening)

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10
Q

What is Tertiary Prevention?

A

Interventions that reduce impairment, minimize pain, and suffering, and prevent death in people with symptomatic health problems (Surgery, Rehab)

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11
Q

What is Disease?

A

Presence of signs or symptoms of poor health

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12
Q

What is Disorder?

A

Functional impairment that may or may not be characterized by measurable structural and psychological changes

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13
Q

What is Mortality?

A

Deaths

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14
Q

What is Morbidity?

A

Non fatal illnesses

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15
Q

What is Testability?

A

The ability of a research question to be answered using experiments or other types of measurements

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16
Q

What is Vital Statistics?

A

Population level measurements

17
Q

What is Abstract?

A

1 page summary of an article

18
Q

What is Internal Validity?

A

The evidence that a study measured what is intended to measure

19
Q

What is External Validity?

A

Generalizability

20
Q

What is Annotated Bibliography?

A

List of related publications that includes at minimum, a full reference for each document being reviewed

21
Q

What is Originality?

A

Aspects of a new research project that are novel (new)

22
Q

What is Replicability?

A

A study implemented in a new study population would yield same results

23
Q

What is the Nuremberg Code?

A

In 1947, a mandated voluntary consent for experimental studies using human subject

24
Q

What is Declaration of Helsinki?

A

Provides ethical guidelines for physicians conducting clinical trials

25
Q

What is the Belmont Report?

A

Defined the key principles of beneficence, respect for persons and distributive justice

26
Q

What is Respect for Persons?

A

Emphasizes autonomy, voluntary ness and protection of vulnerable adults

27
Q

What is Beneficence?

A

Maximum possible benefits and minimize possible harms

28
Q

What is Nonmaleficence?

A

Do no harm

29
Q

What is Distributive Justice?

A

The benefits and burdens of research should be fairly allocated

30
Q

What is Informed Consent?

A

A PROCESS, not a dementia - an individual’s voluntary decision to participate in a research study after reviewing essential information on the study

31
Q

What is Waiver of Consent?

A

Gives the researcher’s permission not to provide an informed consent (low-risk studies)

32
Q

What is Privacy?

A

The assurance that individuals get to choose what information they reveal about themselves

33
Q

What is Confidentiality?

A

Protection of personal information provided to researchers

34
Q

What is Certificate of Confidentiality?

A

A legal document that protects the identity of participants in a study of sensitive topics from being subject to court orders and other legal demands of information

35
Q

What is Assent?

A

Expressed willingness to participate in a study by a child or another person who is deemed not legally competent to provide their own consent

36
Q

What is Expedited Review?

A

Determination by an IRB that a proposal requires review but not a review by a full Comintern.

  • Happens when a minor change to the study has happened
  • Exemptions from this review is NOT allowed for research on VULNERABLE POPULATIONS
37
Q

What is Text- Recycling?

A

“Self Plagiarism” which occurs when one’s own words from one publications are copied into a new manuscript

38
Q

What is the Common Rule?

A

Foundational document for the US

Belmont Report